Dual role of Mic10 in mitochondrial cristae organization and ATP synthase-linked metabolic adaptation and respiratory growth

MICOS and the mitochondrial inner membrane morphology – when things get out of shape

(2021) Indrani Mukherjee et al.   FEBS LETTERS

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Mitochondrial Contact Site and Cristae Organization System and F 1 F O -ATP Synthase Crosstalk Is a Fundamental Property of Mitochondrial Cristae

(2021) Lawrence Rudy Cadena et al.   mSphere

Shaping the mitochondrial inner membrane in health and disease

(2020) L. Colina‐Tenorio et al.   JOURNAL OF INTERNAL MEDICINE

Absolute yeast mitochondrial proteome quantification reveals trade-off between biosynthesis and energy generation during diauxic shift

(2020) Francesca Di Bartolomeo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial pyruvate and fatty acid flux modulate MICU1-dependent control of MCU activity

(2020) Neeharika Nemani et al.   Science Signaling

MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation

(2020) Till Stephan et al.   EMBO JOURNAL

Lactate Elicits ER-Mitochondrial Mg2+ Dynamics to Integrate Cellular Metabolism

(2020) Cassidy C. Daw et al.   CELL

Cryo-EM structure of the entire mammalian F-type ATP synthase

(2020) Gergely Pinke et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the dimeric ATP synthase from bovine mitochondria

(2020) Tobias E. Spikes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maintenance of Cardiolipin and Crista Structure Requires Cooperative Functions of Mitochondrial Dynamics and Phospholipid Transport

(2019) Rieko Kojima et al.   Cell Reports

Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows

(2019) Thorsten B. Blum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Mechanisms of F-Type ATP Synthases

(2019) Werner Kühlbrandt   Annual Review of Biochemistry

Mic60 exhibits a coordinated clustered distribution along and across yeast and mammalian mitochondria

(2019) Stefan Stoldt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent

(2019) Dane M Wolf et al.   EMBO JOURNAL

The ‘mitochondrial contact site and cristae organising system’ (MICOS) in health and human disease

(2019) Matthew J Eramo et al.   JOURNAL OF BIOCHEMISTRY

Revisiting the Crabtree/Warburg effect in a dynamic perspective: a fitness advantage against sugar-induced cell death

(2018) Elisabetta de Alteriis et al.   CELL CYCLE

USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis

(2018) Emanuele Barca et al.   HUMAN MOLECULAR GENETICS

­­Mitochondrial ATP synthase dimers spontaneously associate due to a long-range membrane-induced force­

(2018) Claudio Anselmi et al.   JOURNAL OF GENERAL PHYSIOLOGY

Assembly of the Mitochondrial Cristae Organizer Mic10 Is Regulated by Mic26–Mic27 Antagonism and Cardiolipin

(2018) Heike Rampelt et al.   JOURNAL OF MOLECULAR BIOLOGY

Assembly of the membrane domain of ATP synthase in human mitochondria

(2018) Jiuya He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca 2+ Stress

(2018) Neeharika Nemani et al.   Cell Reports

The Diverged Trypanosome MICOS Complex as a Hub for Mitochondrial Cristae Shaping and Protein Import

(2018) Iosif Kaurov et al.   CURRENT BIOLOGY

The MICOS component Mic60 displays a conserved membrane-bending activity that is necessary for normal cristae morphology

(2017) Daryna Tarasenko et al.   JOURNAL OF CELL BIOLOGY

Mic10, a Core Subunit of the Mitochondrial Contact Site and Cristae Organizing System, Interacts with the Dimeric F 1 F o -ATP Synthase

(2017) Heike Rampelt et al.   JOURNAL OF MOLECULAR BIOLOGY

Atomic model for the dimeric FOregion of mitochondrial ATP synthase

(2017) Hui Guo et al.   SCIENCE

Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions

(2017) Manuel Hessenberger et al.   Nature Communications

Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale

(2017) Marcel Morgenstern et al.   Cell Reports

Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila

(2017) Tobias Brandt et al.   eLife

Evolution and structural organization of the mitochondrial contact site (MICOS) complex and the mitochondrial intermembrane space bridging (MIB) complex

(2016) Martijn A. Huynen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The MICOS complex of human mitochondria

(2016) Vera Kozjak-Pavlovic   CELL AND TISSUE RESEARCH

AtMic60 Is Involved in Plant Mitochondria Lipid Trafficking and Is Part of a Large Complex

(2016) Morgane Michaud et al.   CURRENT BIOLOGY

MICOS and phospholipid transfer by Ups2–Mdm35 organize membrane lipid synthesis in mitochondria

(2016) Mari J. Aaltonen et al.   JOURNAL OF CELL BIOLOGY

Distinct Roles of Mic12 and Mic27 in the Mitochondrial Contact Site and Cristae Organizing System

(2016) Ralf M. Zerbes et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology

(2016) Alexander Hahn et al.   MOLECULAR CELL

Mitochondrial Cristae: Where Beauty Meets Functionality

(2016) Sara Cogliati et al.   TRENDS IN BIOCHEMICAL SCIENCES

An evidence based hypothesis on the existence of two pathways of mitochondrial crista formation

(2016) Max E Harner et al.   eLife

Mic10 Oligomerizes to Bend Mitochondrial Inner Membranes at Cristae Junctions

(2015) Mariam Barbot et al.   Cell Metabolism

Central Role of Mic10 in the Mitochondrial Contact Site and Cristae Organizing System

(2015) Maria Bohnert et al.   Cell Metabolism

The Ca2+-Dependent Release of the Mia40-Induced MICU1-MICU2 Dimer from MCU Regulates Mitochondrial Ca2+ Uptake

(2015) Carmelina Petrungaro et al.   Cell Metabolism

Ancient Homology of the Mitochondrial Contact Site and Cristae Organizing System Points to an Endosymbiotic Origin of Mitochondrial Cristae

(2015) Sergio A. Muñoz-Gómez et al.   CURRENT BIOLOGY

Comprehensive Temporal Protein Dynamics during the Diauxic Shift inSaccharomyces cerevisiae

(2015) J. Patrick Murphy et al.   MOLECULAR & CELLULAR PROTEOMICS

The Oxidation Status of Mic19 Regulates MICOS Assembly

(2015) Paulina Sakowska et al.   MOLECULAR AND CELLULAR BIOLOGY

Mitofilin and CHCHD6 physically interact with Sam50 to sustain cristae structure

(2015) Chengli Ding et al.   Scientific Reports

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

(2015) Jonathan R Friedman et al.   eLife

QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology

(2015) Virginia Guarani et al.   eLife

AQUA Cloning: A Versatile and Simple Enzyme-Free Cloning Approach

(2015) Hannes M. Beyer et al.   PLoS One

Effects of Fcj1-Mos1 and mitochondrial division on aggregation of mitochondrial DNA nucleoids and organelle morphology

(2013) Kie Itoh et al.   MOLECULAR BIOLOGY OF THE CELL

Human F1F0 ATP Synthase, Mitochondrial Ultrastructure and OXPHOS Impairment: A (Super-)Complex Matter?

(2013) Johann Habersetzer et al.   PLoS One

MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival

(2012) Karthik Mallilankaraman et al.   CELL

Role of MINOS in Mitochondrial Membrane Architecture: Cristae Morphology and Outer Membrane Interactions Differentially Depend on Mitofilin Domains

(2012) Ralf M. Zerbes et al.   JOURNAL OF MOLECULAR BIOLOGY

Sam50 Functions in Mitochondrial Intermembrane Space Bridging and Biogenesis of Respiratory Complexes

(2012) C. Ott et al.   MOLECULAR AND CELLULAR BIOLOGY

The C-terminal domain of Fcj1 is required for formation of crista junctions and interacts with the TOB/SAM complex in mitochondria

(2012) Christian Körner et al.   MOLECULAR BIOLOGY OF THE CELL

Role of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane

(2012) Maria Bohnert et al.   MOLECULAR BIOLOGY OF THE CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Structure of the yeast F1Fo-ATP synthase dimer and its role in shaping the mitochondrial cristae

(2012) K. M. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MINOS Is Plus: A Mitofilin Complex for Mitochondrial Membrane Contacts

(2011) Johannes M. Herrmann   DEVELOPMENTAL CELL

Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis

(2011) Karina von der Malsburg et al.   DEVELOPMENTAL CELL

The mitochondrial contact site complex, a determinant of mitochondrial architecture

(2011) Max Harner et al.   EMBO JOURNAL

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria

(2011) Suzanne Hoppins et al.   JOURNAL OF CELL BIOLOGY

MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization

(2011) Alwaleed K. Alkhaja et al.   MOLECULAR BIOLOGY OF THE CELL

Macromolecular organization of ATP synthase and complex I in whole mitochondria

(2011) K. M. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ChChd3, an Inner Mitochondrial Membrane Protein, Is Essential for Maintaining Crista Integrity and Mitochondrial Function

(2010) Manjula Darshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stepwise Assembly of Dimeric F1Fo-ATP Synthase in Mitochondria Involves the Small Fo-Subunits k and i

(2010) Karina Wagner et al.   MOLECULAR BIOLOGY OF THE CELL

Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Sue/g

(2009) Regina Rabl et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial F1Fo-ATP Synthase: The Small Subunits e and g Associate with Monomeric Complexes to Trigger Dimerization

(2009) Karina Wagner et al.   JOURNAL OF MOLECULAR BIOLOGY

Supramolecular organization of the yeast F1Fo-ATP synthase

(2008) Daniel Thomas et al.   BIOLOGY OF THE CELL

Dimer ribbons of ATP synthase shape the inner mitochondrial membrane

(2008) Mike Strauss et al.   EMBO JOURNAL