Suppression of breast cancer progression by FBXL16 via oxygen-independent regulation of HIF1α stability

The F-box protein FBXL16 up-regulates the stability of C-MYC oncoprotein by antagonizing the activity of the F-box protein FBW7

(2020) Marion Morel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-Induced Epithelial-Mesenchymal Transition in Cancers: HIF-1α and Beyond

(2020) Shing Yau Tam et al.   Frontiers in Oncology

The Regulatory Role of MicroRNAs in Breast Cancer

(2019) Hui-Yi Loh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers

(2019) Kyoungwha Pang et al.   Nature Communications

Molecular and Cellular Response of Co-cultured Cells toward Cobalt Chloride (CoCl2)-Induced Hypoxia

(2019) Vinay Kumar Tripathi et al.   ACS Omega

Loss of function of miR-342-3p results in MCT1 over-expression and contributes to oncogenic metabolic reprogramming in triple negative breast cancer

(2018) Sandra L. Romero-Cordoba et al.   Scientific Reports

Molecular alterations in triple-negative breast cancer—the road to new treatment strategies

(2017) Carsten Denkert et al.   LANCET

LRG1 modulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via HIF-1α activation

(2016) Jingjing Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer

(2016) Aifu Lin et al.   NATURE CELL BIOLOGY

MicroRNA regulation of F-box proteins and its role in cancer

(2016) Zhao-Hui Wu et al.   SEMINARS IN CANCER BIOLOGY

F-box protein interactions with the hallmark pathways in cancer

(2016) Suzanne J. Randle et al.   SEMINARS IN CANCER BIOLOGY

Hypoxia-inducible factor 1 and breast cancer metastasis

(2015) Zhao-ji Liu et al.   Journal of Zhejiang University-SCIENCE B

Novel genes associated with lymph node metastasis in triple negative breast cancer

(2015) Andrea Mathe et al.   Scientific Reports

F-box Protein FBXL16 Binds PP2A-B55α and Regulates Differentiation of Embryonic Stem Cells along the FLK1+ Lineage

(2014) Narimon Honarpour et al.   MOLECULAR & CELLULAR PROTEOMICS

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

(2014) Xi Chen et al.   NATURE

Elafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors

(2014) S I Labidi-Galy et al.   ONCOGENE

Molecular classification of breast cancer

(2014) Darina Vuong et al.   VIRCHOWS ARCHIV

Endothelial Cell Tube Formation Assay for the In Vitro Study of Angiogenesis

(2014) Katie L. DeCicco-Skinner et al.   Jove-Journal of Visualized Experiments

Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis

(2013) Colin Clarke et al.   CARCINOGENESIS

SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors

(2012) Marco Montagner et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Molecular mechanisms mediating metastasis of hypoxic breast cancer cells

(2012) Gregg L. Semenza   TRENDS IN MOLECULAR MEDICINE

Negative regulation of HIF-1α by an FBW7-mediated degradation pathway during hypoxia

(2011) Jessica M. Cassavaugh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

A gene expression signature identifies two prognostic subgroups of basal breast cancer

(2010) Renaud Sabatier et al.   BREAST CANCER RESEARCH AND TREATMENT

Extended Ischemia Prevents HIF1α Degradation at Reoxygenation by Impairing Prolyl-hydroxylation

(2010) Anna Serra-Pérez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficacy of Neoadjuvant Cisplatin in Triple-Negative Breast Cancer

(2010) Daniel P. Silver et al.   JOURNAL OF CLINICAL ONCOLOGY

Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer

(2010) Yang Li et al.   NATURE MEDICINE

Gene expression signatures in breast cancer distinguish phenotype characteristics, histologic subtypes, and tumor invasiveness

(2009) Vincente Pedraza et al.   CANCER

KLF5 Promotes Breast Cell Survival Partially through Fibroblast Growth Factor-binding Protein 1-pERK-mediated Dual Specificity MKP-1 Protein Phosphorylation and Stabilization

(2009) Rong Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting the ubiquitin-proteasome system for cancer therapy

(2008) Yili Yang et al.   CANCER SCIENCE

Role and regulation of prolyl hydroxylase domain proteins

(2008) G-H Fong et al.   CELL DEATH AND DIFFERENTIATION