4.7 Article

Machine learning-aided risk prediction for metabolic syndrome based on 3 years study

Journal

SCIENTIFIC REPORTS
Volume 12, Issue 1, Pages -

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41598-022-06235-2

Keywords

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Funding

  1. Blue Fire Innovation Project of the Ministry of Education (Huizhou) [CXZJHZ201803]
  2. Natural Science Foundation of Guangdong Province [2019A1515011940]
  3. Science & Technology Project of Guangzhou [202002030353]

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In this study, the risk prediction for Metabolic syndrome (MetS) was investigated using a large dataset. The differential state feature (DSF) was found to significantly contribute to the risk prediction of MetS. The proposed scheme outperformed the state-of-the-art models and showed potential for effectively screening the occurrence of MetS.
Metabolic syndrome (MetS) is a group of physiological states of metabolic disorders, which may increase the risk of diabetes, cardiovascular and other diseases. Therefore, it is of great significance to predict the onset of MetS and the corresponding risk factors. In this study, we investigate the risk prediction for MetS using a data set of 67,730 samples with physical examination records of three consecutive years provided by the Department of Health Management, Nanfang Hospital, Southern Medical University, P.R. China. Specifically, the prediction for MetS takes the numerical features of examination records as well as the differential features by using the examination records over the past two consecutive years, namely, the differential numerical feature (DNF) and the differential state feature (DSF), and the risk factors of the above features w.r.t different ages and genders are statistically analyzed. From numerical results, it is shown that the proposed DSF in addition to the numerical feature of examination records, significantly contributes to the risk prediction of MetS. Additionally, the proposed scheme, by using the proposed features, yields a superior performance to the state-of-the-art MetS prediction model, which provides the potential of effective prescreening the occurrence of MetS.

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