Article
Biochemistry & Molecular Biology
Rong Gao, Bohang An, Cen Zhou, Xiao Zhang
Summary: A new triazaisotruxene-based porous organic polymer with good thermal stability was designed and synthesized as a promising adsorbent for iodine in various solutions.
Article
Engineering, Environmental
Changqing Miao, Lichao Chu, Di Guo, Xin Ding, Wenxue Guo, Shaoyu Wang, Jiwen Sheng, Jian Zhang, Zengyao Wang, Baolong Zhou
Summary: Water pollution is a global issue that seriously threatens the health of living beings. In this study, a multifunctional porous polymer, Fc-PP-POP, was successfully prepared, which exhibited enhanced antibacterial effect and iodine pollutant capture. This polymer combined the photoactivity of porphyrin with the enzymatic activity of ferrocene, enabling efficient conversion of light energy into thermal energy for photothermal therapy and transformation of low concentration H2O2 into toxic hydroxyl radicals for enzyme therapy. In addition, Fc-PP-POP promoted wound healing and efficiently adsorbed iodine contaminants from the environment.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Polymer Science
Siqi Chang, Wei Xie, Chan Yao, Guangjuan Xu, Shuran Zhang, Yanhong Xu
Summary: In this study, three monomers were used to synthesize a series of stable CTFs with multiple active sites, showing promising performance in iodine capture and CO2 adsorption. The introduction of electron-rich groups enhanced the iodine adsorption capacity of the polymers, indicating potential applications in CO2 capture.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Polymer Science
Pedro M. C. Matias, Dina Murtinho, Artur J. M. Valente
Summary: The scientific community is developing materials called porous organic polymers (POPs) that are custom-built at the molecular level and have low densities, high stability, surface areas, and porosity. This paper focuses on the synthesis, characterization, and performance of three triazine-based POPs (T-POPs) in dye adsorption and catalysis. The T-POPs showed excellent efficiency in removing anionic and cationic dyes from water, as well as high conversions and selectivities in Henry reactions when modified with copper(II).
Article
Nanoscience & Nanotechnology
Ningning Liu, Hui Ma, Ruixue Sun, Qing-Pu Zhang, Bien Tan, Chun Zhang
Summary: A three-dimensional rigid six-connected porous triptycene network was successfully synthesized using triptycenes as connectors and Tro''ger's base as linkers. The network exhibits a high surface area (1528m² g⁻¹), nitrogen-enriched groups, and superior thermal stability, leading to a high CO₂ uptake of 22.3 wt % (273 K, 1 bar) and excellent iodine vapor adsorption of 240 wt %.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Polymer Science
Bingyan Zhou, Zixu Chen, Shengyu Feng, Dengxu Wang, Hongzhi Liu
Summary: The development of alkynyl imine-containing porous organic polymers by a one-pot multicomponent polymerization reaction has shown promising potential for efficient iodine capture, with the ability to tune the iodine capture performances by altering the content of alkynyl imine groups in the networks. The adsorption mechanism involves chemisorption and physisorption, paving a new way for developing porous polymers with intriguing functionality and applications.
Article
Materials Science, Multidisciplinary
Changqing Miao, Nailing Tang, Lin Shi, Shaoyu Wang, Pengpeng Ji, Jian Zhang, Zengyao Wang, Baolong Zhou
Summary: This study presents the preparation of a magnetic ionic porous organic polymer with sustainable and recyclable capacity for purifying polluted water. The material showed high efficiency in killing bacteria and capturing radioactive iodine, and it could be easily recovered and regenerated without performance degradation. The unique structure of the material, including its magnetic properties, endowed it with prominent antimicrobial activity and diffusion antibacterial effect.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Applied
Cheng Yan, Yue Wu, Haifeng Lu, Hailong Liu, Gang Yi, Mei Li, Xiaoxia Cai, Sheng Gao, Zhizhou Yang
Summary: Novel phenothiazine-based hyper-cross-linked porous polymers (PZ-HCPs) with high iodine capture ability were synthesized using Friedel-Crafts alkylation reaction and exhibited a specific surface area ranging from 131 m(2) g(-1) to 209 m(2) g(-1). This study provides a strategy for synthesizing HCPs as adsorbents for the treatment of radioactive iodine in nuclear waste.
MICROPOROUS AND MESOPOROUS MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Yalin Huang, Wei Li, Yuwei Xu, Mu Ding, Jie Ding, Yun Zhang, Yuanhua Wang, Shanyong Chen, Yongdong Jin, Chuanqin Xia
Summary: The study presents the successful synthesis of a nitrogen-rich porous polymer, n-CTP, with high efficiency in capturing radioiodine. n-CTP exhibits a rapid adsorption rate, excellent uptake capacity, and potential application in nuclear waste treatment and emergency response to nuclear accidents.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Nanoscience & Nanotechnology
Sayantan Sarkar, Tanushree Ghosh, Argha Chakrobarty, Jagannath Majhi, Probal Nag, Anasuya Bandyopadhyay, Sivaranjana Reddy Vennapusa, Rajesh Kumar, Suman Mukhopadhyay
Summary: Here, a redox-active multifunctional ionic porous organic polymer iPOP-Bpy with exchangeable Br- ions, incorporating viologen as a redox-active building block, is designed and synthesized. The material exhibits excellent iodine uptake capacity in vapor phase (540 wt %) as well as in organic (1009.77 mg g(-1)) and aqueous phases (3921.47 mg g(-1)) with very fast adsorption kinetics. It also functions as a solid-state NH3 vapor sensor, showing rapid color switching in the presence of NH3 vapor. Moreover, it is used as a p-type complementary electrochromic electrode and shows promising performance for fabricating power-efficient solid-state electrochromic devices.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Materials Science, Multidisciplinary
Shaohui Xiong, Haowen Huang, Tianzhi Tang, Xinxiu Cao, Hongwei Zhao, Gen Li, Huan Liu, Weijie Zhang, Qingquan Liu
Summary: Two types of triazine-based covalent organic polymers with high adsorption performance and stability were successfully constructed through a catalyst-free polycondensation approach. These polymers offer an alternative route for capturing carbon dioxide and iodine.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Chemistry, Applied
Mosim Ansari, Atikur Hassan, Akhtar Alam, Neeladri Das
Summary: Coal-fired and thermal power plants are major contributors to CO2 emissions, leading to global warming and ocean acidification. Solutions like carbon capture or nuclear energy are being explored. A new porous polymer, TBHCP-OH, shows promising potential for environmental remediation by efficiently capturing CO2 and iodine vapor.
MICROPOROUS AND MESOPOROUS MATERIALS
(2021)
Review
Engineering, Chemical
Jiajia Wang, Lizhi Wang, You Wang, Du Zhang, Qin Xiao, Jianhan Huang, You-Nian Liu
Summary: Carbon capture, storage, and utilization (CCSU) is an effective method for reducing CO2 emissions. Amine aqueous solutions are efficient for CO2 capture due to their large capacity and high selectivity. However, solid adsorbents have gained attention in recent years for CO2 adsorption due to their simplicity and high efficiency. Porous organic polymers (POPs) have shown promise as solid adsorbents for CO2 capture due to their high surface area, adjustable pore size, and easy functionalization. This review provides a detailed overview of different POPs developed in recent years, discussing their design strategies, unique structures, and highlighting the opportunities and challenges associated with POPs.
CHINESE JOURNAL OF CHEMICAL ENGINEERING
(2022)
Article
Materials Science, Multidisciplinary
Santosh Kumar, Atikur Hassan, Neeladri Das, Joonseok Koh
Summary: The increasing levels of CO2 in the atmosphere have led to serious problems. In this study, nano architectonics porous organic polymers (NPOPs) were synthesized by a catalyst-free coupling reaction for CO2 capture. The NPOPs showed thermal stability and a large surface area, indicating potential application in carbon capture and storage technology.
Article
Chemistry, Multidisciplinary
Jialing Wu, Sijia Di, Wei Huang, Yunling Wu, Qiliang Huang, Xuan Zhao, Xiaohan Yu, Mochun Zhang, Hualin Ye, Yanguang Li
Summary: Porous polyimide frameworks (PIFs) based on perylene and triazine have been identified as a promising anode material for potassium-ion batteries, offering high reversible specific capacity, good rate performance, and long cycling stability.
MATERIALS CHEMISTRY FRONTIERS
(2021)
Article
Multidisciplinary Sciences
Muhammad A. Sabri, Mohammad H. Al-Sayah, Susan Sen, Taleb H. Ibrahim, Oussama M. El-Kadri
SCIENTIFIC REPORTS
(2020)
Article
Environmental Sciences
A. Karami, R. Sabouni, M. H. Al-Sayah, A. Aidan
Summary: The study investigated the efficiency of Fe-BTC for removing methyl orange as a model contaminant, showing high removal efficiency over a wide pH range. Fixed-bed column studies revealed breakthrough times, removal efficiencies, and maximum uptakes at different bed depths, with good agreement between experimental and theoretical models. Fe-BTC demonstrated potential for industrial applications based on the results obtained.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Muhammad A. Sabri, Ziad Sara, Mohammad H. Al-Sayah, Taleb H. Ibrahim, Mustafa I. Khamis, Oussama M. El-Kadri
Summary: Two novel nitrogen-rich aminal linked porous organic polymers, NRAPOP-O and NRAPOP-S, were synthesized and showed excellent thermal stability and high porosity for efficient removal of Cr(VI) from solution by simultaneous reduction to Cr(III). At optimal conditions, NRAPOP-O achieved 100% removal of Cr(VI) with 80% efficiency in releasing Cr(III) into the solution, and the polymers can be easily regenerated without significant loss.
Article
Multidisciplinary Sciences
Amal Elamir, Saniha Ajith, Nour Al Sawaftah, Waad Abuwatfa, Debasmita Mukhopadhyay, Vinod Paul, Mohammad H. Al-Sayah, Nahid Awad, Ghaleb A. Husseini
Summary: Functionalizing liposomes with monoclonal antibodies, particularly anti-HER2 antibodies, can enhance targeted drug delivery to HER2 positive breast cancer cells. Low frequency ultrasound (LFUS) triggered drug release from liposomes can be further enhanced by the conjugation of Trastuzumab, increasing drug uptake and cellular toxicity in HER2+ cell lines. Combining immunoliposomes with LFUS is a promising technique to improve drug delivery efficiency and reduce cytotoxicity of antineoplastic drugs.
SCIENTIFIC REPORTS
(2021)
Review
Biochemistry & Molecular Biology
Remya Radha, Syeda Kiran Shahzadi, Mohammad Hussein Al-Sayah
Summary: Cardiovascular diseases are a major cause of global human death, with myocardial infarction (MI) having the highest morbidity and mortality rates. Cardiac troponin is considered the gold standard as a specific biomarker for cardiac injury, with fluorescence-based immunoassays being the fastest, most accurate, and most sensitive method for detecting cardiac troponins post-MI.
Article
Multidisciplinary Sciences
Nour M. AlSawaftah, Nahid S. Awad, Vinod Paul, Paul S. Kawak, Mohammad H. Al-Sayah, Ghaleb A. Husseini
Summary: Targeted liposomes triggered with ultrasound enable controlled drug release and reduce side effects. Transferrin-conjugated pegylated liposomes are more sensitive to ultrasound and exhibit higher drug uptake ability.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Remya Radha, Mohammad Hussein Al-Sayah
Summary: The study developed an efficient fluorescent sandwich immunoassay for sensing and quantifying serum cTnI in clinical settings. The assay showed sensitivity and selectivity towards cTnI, with a detection limit of 6.5 ng/mL in spiked human serum samples.
Article
Chemistry, Analytical
Remya Radha, Rute F. Vitor, Mohammad Hussein Al-Sayah
Summary: This study reports a carbazole-based biosensor for the detection of melamine in aqueous solutions. The results suggest that this novel sensor can detect melamine even at very low concentrations.
Article
Energy & Fuels
Abdollah Karami, Reem Shomal, Rana Sabouni, Mohammad H. Al-Sayah, Ahmed Aidan
Summary: Wastewater treatment plants are one of the most energy-intensive industries, with every stage of treatment consuming energy. Metal-organic frameworks have superior properties that can enhance separation performance, leading to improved dye removal in water treatment. Fe-BTC showed the highest removal efficiency among the investigated MOFs for methyl orange removal.
Review
Chemistry, Multidisciplinary
Amaal Abdulraqeb Ali, Amani Al-Othman, Mohammad H. Al-Sayah
Summary: Hybrid nanogels are emerging as novel and multifunctional cancer therapeutic strategies, with the potential to possess cytotoxic effects, carry drugs/enzymes, improve imaging, and target tumor cells. Despite their promising abilities, their clinical application is limited and further research is needed. Factors affecting their future include lack of hemocompatibility studies, toxicological evaluations, and information on tumor heterogeneity and interaction with physiological fluids.
JOURNAL OF CONTROLLED RELEASE
(2022)
Review
Chemistry, Multidisciplinary
Amaal Abdulraqeb Ali, Waad H. Abuwatfa, Mohammad H. Al-Sayah, Ghaleb A. Husseini
Summary: Researchers believe that gold nanoparticle (GNP) hybrid nanostructures are promising multimodal candidates for cancer therapy, as they can achieve chemotherapy, photothermal therapy, radiotherapy, and imaging using a single composite. However, there is currently a lack of reviews summarizing the use of GNP nanohybrids for cancer treatment. Therefore, this review provides a critical analysis of GNP nanohybrid use in cancer therapy, with a focus on synergistic approaches.
Review
Infectious Diseases
Zinb Makhlouf, Amaal Abdulraqeb Ali, Mohammad Hussein Al-Sayah
Summary: Currently approved antibiotics face varying degrees of resistance from targeted bacteria. Biofilm formation is an important factor enabling bacterial resistance, and targeting this process is crucial for overcoming antibiotic resistance. Lipid-based nanocarriers (liposomes), among other drug delivery systems, have shown effectiveness against biofilms of medically significant gram-negative and gram-positive bacterial species.
Article
Nanoscience & Nanotechnology
Safa M. Ben Daya, Vinod Paul, Nahid S. Awad, Nour M. Al Sawaftah, Mohammad H. Al Sayah, Ghaleb A. Husseini
Summary: Combining hyaluronic acid with liposomes can enhance targeting and drug uptake in breast cancer cells, with significant improvements seen when low-frequency ultrasound is applied. This approach shows promise as a drug delivery platform in breast cancer treatment.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2021)
Proceedings Paper
Engineering, Biomedical
Nader Lutfi Almufleh, Amani Al-Othman, Hasan Al-Nashash, Mohammed Hussein Al-Sayah
2020 IEEE 5TH MIDDLE EAST AND AFRICA CONFERENCE ON BIOMEDICAL ENGINEERING (MECBME)
(2020)