Experimental Animal Studies Support the Role of Dietary Advanced Glycation End Products in Health and Disease

Dietary advanced glycation endproducts (AGEs) increase their concentration in plasma and tissues, result in inflammation and modulate gut microbial composition in mice; evidence for reversibility

(2021) Katja C.W. van Dongen et al.   FOOD RESEARCH INTERNATIONAL

Altered hepatic sphingolipid metabolism in insulin resistant mice: Role of advanced glycation endproducts

(2021) Raffaella Mastrocola et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dietary Advanced Glycation End Products (AGEs) could alter ovarian function in mice

(2020) Kimberly Thornton et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Glycolaldehyde-modified proteins cause adverse functional and structural aortic remodeling leading to cardiac pressure overload

(2020) Sibren Haesen et al.   Scientific Reports

Metabolic transit of dietary advanced glycation end-products - the case of NƐ-carboxymethyllysine

(2020) Frederic J. Tessier et al.   GLYCOCONJUGATE JOURNAL

Diet with high content of advanced glycation end products induces systemic inflammation and weight gain in experimental mice: Protective role of curcumin and gallic acid

(2018) Boopathi Sowndhar Rajan et al.   FOOD AND CHEMICAL TOXICOLOGY

Aging and glycoxidant stress

(2018) Melpomeni Peppa et al.   Hormones-International Journal of Endocrinology and Metabolism

Western diet given to healthy rats mimics the human phenotype of diabetic cardiomyopathy

(2018) Maxim Verboven et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Redox Balance, Antioxidant Defense, and Oxidative Damage in the Hypothalamus and Cerebral Cortex of Rats with High Fat Diet-Induced Insulin Resistance

(2018) Mateusz Maciejczyk et al.   Oxidative Medicine and Cellular Longevity

Dietary Advanced Glycation End Products Have Sex- and Age-Dependent Effects on Vertebral Bone Microstructure and Mechanical Function in Mice

(2017) Svenja Illien-Jünger et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Advanced glycation end products (AGEs) increase renal lipid accumulation: a pathogenic factor of diabetic nephropathy (DN)

(2017) Yang Yuan et al.   Lipids in Health and Disease

Dietary advanced glycation end products modify gut microbial composition and partially increase colon permeability in rats

(2017) Wanting Qu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction

(2017) Danielle J. Borg et al.   Islets

Advanced Glycation End-Products: A Biological Consequence of Lifestyle Contributing to Cancer Disparity

(2015) D. P. Turner   CANCER RESEARCH

Dietary consumption of advanced glycation end products and pancreatic cancer in the prospective NIH-AARP Diet and Health Study

(2014) Li Jiao et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Dietary Intake of Advanced Glycation End Products Did Not Affect Endothelial Function and Inflammation in Healthy Adults in a Randomized Controlled Trial

(2014) Richard D. Semba et al.   JOURNAL OF NUTRITION

Dietary advanced glycation end products are associated with decline in memory in young elderly

(2014) Rebecca K. West et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Dietary advanced glycation end-product restriction for the attenuation of insulin resistance, oxidative stress and endothelial dysfunction: a systematic review

(2013) N J Kellow et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

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(2013) Eleni Kandaraki et al.   MOLECULAR MEDICINE

Methylglyoxal Induces Tau Hyperphosphorylation via Promoting AGEs Formation

(2012) Xiao-Hong Li et al.   NEUROMOLECULAR MEDICINE

Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1

(2012) W. Cai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advanced Glycation End Products Are Direct Modulators of  -Cell Function

(2011) M. T. Coughlan et al.   DIABETES

AGE restriction in diabetes mellitus: a paradigm shift

(2011) Helen Vlassara et al.   Nature Reviews Endocrinology

Advanced Glycation End Products in Foods and a Practical Guide to Their Reduction in the Diet

(2010) Jaime Uribarri et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Protection against Loss of Innate Defenses in Adulthood by Low Advanced Glycation End Products (AGE) Intake: Role of the Antiinflammatory AGE Receptor-1

(2009) Helen Vlassara et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Advanced glycoxidation products and impaired diabetic wound healing

(2009) Melpomeni Peppa et al.   WOUND REPAIR AND REGENERATION

Oral Glycotoxins Determine the Effects of Calorie Restriction on Oxidant Stress, Age-Related Diseases, and Lifespan

(2008) Weijing Cai et al.   AMERICAN JOURNAL OF PATHOLOGY