Article
Chemistry, Multidisciplinary
Jieying Liang, Song Gao, Jian Liu, Muhammad Y. B. Zulkifli, Jiangtao Xu, Jason Scott, Vicki Chen, Jiafu Shi, Aditya Rawal, Kang Liang
Summary: Hierarchically porous MOFs were constructed by controlled structural etching to enhance multienzyme and cofactor-dependent enzyme biocatalysis, which provided sufficient space for enzymes to reorientate and spread within MOFs and effectively accelerate the diffusion rate of reactants and intermediates, showing outstanding tolerance to inhospitable surroundings and recyclability.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Lin Wang, Shu-Rong Li, Yu-Zhen Chen, Hai-Long Jiang
Summary: In this work, nanocrystals of Cu2O were encapsulated by metal-organic frameworks (MOFs) through a simple strategy, resulting in the successful fabrication of Cu@HKUST-1 composites with uniform morphology and controlled MOF thickness. The integration of Cu NCs properties with MOF advantages helped to create a multifunctional catalyst, exhibiting cooperative catalytic activity and improved recyclability.
Article
Chemistry, Multidisciplinary
Si Liu, Yan Sun
Summary: A facile and versatile polyelectrolyte-assisted encapsulation approach is presented, which enables the confinement of a cofactor-dependent multienzyme cascade within hydrogen-bonded organic frameworks. The system features excellent cargo loading, cascade activity recovery, and cofactor recycling capabilities.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Ilya Sterin, John Hadynski, Anna Tverdokhlebova, Madeline Masi, Evgeny Katz, Mario Wriedt, Oleh Smutok
Summary: This study investigates a metal-organic framework (MOF) called ZIF-8, which remains stable in neutral pH aqueous solutions but dissolves under acidic conditions. By electrochemical or enzymatic reactions, the pH can be decreased to induce MOF dissolution and payload release. The results suggest that signal-responsive materials with switchable features can be used to deliver biomolecules in biomedical applications.
ADVANCED MATERIALS
(2023)
Review
Biochemistry & Molecular Biology
Wei Huang, Siming Huang, Guosheng Chen, Gangfeng Ouyang
Summary: Metal-organic frameworks (MOFs) have been intelligently employed as supports to protect enzymes and provide alternative routes for constructing robust enzyme mimics.
Article
Chemistry, Multidisciplinary
Zhuangyan Guo, Shuai Yang, Minghao Liu, Qing Xu, Gaofeng Zeng
Summary: In this study, core-shelled hybrids of covalent organic frameworks and metal-organic frameworks are constructed to catalyze the oxygen evolution reaction. The high oxygen evolution reaction activity in the core-shelled Co-COF@MOF catalyst is due to the synergetic roles between the Co and Fe sites, which promote the formation of O* from OH*.
Article
Engineering, Biomedical
Caiqi Yang, Wen Liu, Shanfeng Chen, Xiaoqing Zong, Pengfei Yuan, Xinjie Chen, Xiaodi Li, Yuchao Li, Wei Xue, Jian Dai
Summary: A biomineralization strategy was used to fabricate a two-in-one engineered glucose oxidase (GOx-Fe-0) with a nanozyme anchored within its inner cavity. The GOx-Fe-0 was then immobilized in a pH-sensitive metal-organic framework (MOF) zeolitic imidazolate framework-8 (ZIF-8) to establish a stable and effective MOF-immobilized two-in-one engineered enzyme, GOx-Fe-0@ZIF-8. In vitro and in vivo studies demonstrated that this enzyme had excellent stability, selectivity, and catalytic efficiency for biocatalytic cascade reactions.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Yan Zhang, Bi-Cong Wang, Po Wang, Xiao-Jie Ju, Mao-Jie Zhang, Rui Xie, Zhuang Liu, Wei Wang, Liang-Yin Chu
Summary: Researchers developed uniform hydrogel microparticles with MOF nanoparticles for molecular co-confinement of cascade enzymes using droplet microfluidics, achieving enhanced stability and reusability under harsh conditions. This strategy provides a simple and efficient way to create multiple-enzyme-loaded microcarriers for biocatalytic cascades.
REACTION CHEMISTRY & ENGINEERING
(2022)
Article
Chemistry, Physical
Kara E. Metzger, Megan M. Moyer, Brian G. Trewyn
Summary: Recent research on tandem catalysis has focused on designing biosynthetic pathways using enzymes and inorganic catalysts in single-pot systems. By cleverly utilizing porous supports, incompatible enzymes and inorganic catalysts can be successfully integrated to enhance the properties of combined catalysts. Studies have shown that supports can stabilize catalysts and act as active components within the systems. Ongoing research is exploring successful combinations of enzymes and inorganic catalysts supported on porous supports for tandem reactions along with the challenges that still need to be addressed.
Review
Chemistry, Physical
Reuben B. Leveson-Gower, Gerard Roelfes
Summary: Friedel-Crafts alkylation and acylation reactions are important in synthetic and industrial chemistry. Researchers have expanded the application of these reactions through directed evolution and created bio-hybrid catalysts. This review summarizes these efforts and discusses future routes for more efficient and benign Friedel-Crafts reactions.
Article
Chemistry, Multidisciplinary
Shaghayegh Naghdi, Emily Brown, Mohammad Zendehbad, Ann Duong, Wolfgang Ipsmiller, Santu Biswas, Maytal Caspary Toroker, Hossein Kazemian, Dominik Eder
Summary: Selective removal of one ligand in mixed-ligand MOFs creates hierarchical pore architectures with improved adsorption capacity for glyphosate removal from water. The Ti-OH groups resulting from ligand removal serve as effective anchor points for glyphosate uptake. The introduction of additional mesopores has significantly increased the adsorption capacities, making these MOFs among the best-reported adsorbents.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Engineering, Environmental
Shu Xu, Jieying Liang, Munirah Izzah Binti Mohammad, Dongwei Lv, Ying Cao, Jingyao Qi, Kang Liang, Jun Ma
Summary: An original biocatalytic enzyme/metal-organic framework composite membrane has been developed for continuous and efficient removal of micropollutants from aqueous solution, showing enhanced stability and reusability. The hybrid structure design integrates selective separation with stable enzymatic catalysis, achieving desirable decontamination performance and setting a new record of bisphenol A removal efficiency.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Chengfeng Zhu, Keke Yang, Hongzhao Wang, Yu Fang, Liang Feng, Jiaqi Zhang, Zhifeng Xiao, Xiang Wu, Yougui Li, Yanming Fu, Wencheng Zhang, Kun-Yu Wang, Hong-Cai Zhou
Summary: This study reports two porous assemblies, PCC-60 and PCC-67, with different pore structures for efficient enantioselective separation. PCC-60 demonstrates excellent enantioselectivity and recyclability through its hierarchically porous structure with interconnected mesopores.
ACS CENTRAL SCIENCE
(2022)
Article
Chemistry, Inorganic & Nuclear
Guizhen Lu, Chao Huang, Mei Qiu, Qiang Zhang, Siwen Cui, Lin Zhang, Ying-Ying Zhang, Liwei Mi
Summary: In this study, coordination polymers were used as triboelectric materials to expand the application range of triboelectric nanogenerators by utilizing the well-arranged and tunable frameworks of crystalline materials. The electronic structure contributions of different bridging ligands were determined and their effects on the output of TENGs were verified. Additionally, adjusting the concentration of Cd-CP in PVDF composite films effectively enhanced the output performance of TENGs.
INORGANIC CHEMISTRY
(2022)
Review
Chemistry, Physical
Dereje H. Taffa, Danni Balkenhohl, Mandana Amiri, Michael Wark
Summary: This article presents the current research state of using nickel-based metal-organic frameworks (MOFs) as catalyst materials for alkaline electrolysis, discussing strategies for improving catalytic performance and comparing OER activities based on performance metrics. Nickel-based MOFs are demonstrated to have excellent activity and tunability, making them promising catalysts for hydrogen production.