Cofilin1 oxidation links oxidative distress to mitochondrial demise and neuronal cell death

Mitochondrial rescue prevents glutathione peroxidase-dependent ferroptosis

(2018) Anja Jelinek et al.   FREE RADICAL BIOLOGY AND MEDICINE

Brain ischemic insult induces cofilin rod formation leading to synaptic dysfunction in neurons

(2018) Liang Shu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cofilin-actin rod formation in neuronal processes after brain ischemia

(2018) Seok Joon Won et al.   PLoS One

Role of Mitochondria in Ferroptosis

(2018) Minghui Gao et al.   MOLECULAR CELL

DNA damage related crosstalk between the nucleus and mitochondria

(2017) Mohammad Saki et al.   FREE RADICAL BIOLOGY AND MEDICINE

INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division

(2017) Rajarshi Chakrabarti et al.   JOURNAL OF CELL BIOLOGY

Cofilin1-dependent actin dynamics control DRP1-mediated mitochondrial fission

(2017) Katharina Rehklau et al.   Cell Death & Disease

BID links ferroptosis to mitochondrial cell death pathways

(2017) Sandra Neitemeier et al.   Redox Biology

Cofilin-mediated Neuronal Apoptosis via p53 Translocation and PLD1 Regulation

(2017) Tian Liu et al.   Scientific Reports

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis

(2016) S Neitemeier et al.   Cell Death & Disease

Redox regulation of cytoskeletal dynamics during differentiation and de-differentiation

(2015) Manuela Gellert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

ADF/cofilin: a crucial regulator of synapse physiology and behavior

(2015) Marco B. Rust   CELLULAR AND MOLECULAR LIFE SCIENCES

Autism-like Deficits in Shank3-Deficient Mice Are Rescued by Targeting Actin Regulators

(2015) Lara J. Duffney et al.   Cell Reports

The Role of Oxidative Stress in Neurodegenerative Diseases

(2015) Geon Ha Kim et al.   Experimental Neurobiology

Taurine chloramine-induced inactivation of cofilin protein through methionine oxidation

(2014) Shen Luo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cofilin: a redox sensitive mediator of actin dynamics during T-cell activation and migration

(2014) Yvonne Samstag et al.   IMMUNOLOGICAL REVIEWS

Cofilin/Actin Rod Formation by Dysregulation of Cofilin-1 Activity as a Central Initial Step in Neurodegeneration

(2014) Patricia Schonhofen et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

ATP-dependent regulation of actin monomer–filament equilibrium by cyclase-associated protein and ADF/cofilin

(2013) Kazumi Nomura et al.   BIOCHEMICAL JOURNAL

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Inhibition of Drp1 provides neuroprotection in vitro and in vivo

(2012) J Grohm et al.   CELL DEATH AND DIFFERENTIATION

Incorporation of Cofilin into Rods Depends on Disulfide Intermolecular Bonds: Implications for Actin Regulation and Neurodegenerative Disease

(2012) B. W. Bernstein et al.   JOURNAL OF NEUROSCIENCE

ADF/cofilin proteins translocate to mitochondria during apoptosis but are not generally required for cell death signaling

(2011) K Rehklau et al.   CELL DEATH AND DIFFERENTIATION

Impedance measurement for real time detection of neuronal cell death

(2011) S. Diemert et al.   JOURNAL OF NEUROSCIENCE METHODS

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

(2011) Joshua M. Baughman et al.   NATURE

Oxidative stress caused by mitochondrial calcium overload

(2010) Tsung-I Peng et al.   Annals of the New York Academy of Sciences

Reactive Oxygen Species in the Regulation of Synaptic Plasticity and Memory

(2010) Cynthia A. Massaad et al.   ANTIOXIDANTS & REDOX SIGNALING

Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons

(2010) S Tobaben et al.   CELL DEATH AND DIFFERENTIATION

Learning, AMPA receptor mobility and synaptic plasticity depend on n-cofilin-mediated actin dynamics

(2010) Marco B Rust et al.   EMBO JOURNAL

Both Thioredoxin 2 and Glutaredoxin 2 Contribute to the Reduction of the Mitochondrial 2-Cys Peroxiredoxin Prx3

(2010) Eva-Maria Hanschmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ADF/Cofilin: a functional node in cell biology

(2010) Barbara W. Bernstein et al.   TRENDS IN CELL BIOLOGY

Mitochondrial translocation of oxidized cofilin induces caspase-independent necrotic-like programmed cell death of T cells

(2010) G H Wabnitz et al.   Cell Death & Disease

Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death

(2009) Julia Grohm et al.   BRAIN BEHAVIOR AND IMMUNITY

What is the mitochondrial permeability transition pore?

(2009) Andrew P. Halestrap   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Reactive Oxygen Species Regulate a Slingshot-Cofilin Activation Pathway

(2009) Jun-Sub Kim et al.   MOLECULAR BIOLOGY OF THE CELL

Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin

(2009) Fábio Klamt et al.   NATURE CELL BIOLOGY

Mitochondrial membrane permeabilization in neuronal injury

(2009) Lorenzo Galluzzi et al.   NATURE REVIEWS NEUROSCIENCE

Oxidative stress induces degradation of mitochondrial DNA

(2009) Inna Shokolenko et al.   NUCLEIC ACIDS RESEARCH

Bid-induced release of AIF from mitochondria causes immediate neuronal cell death

(2008) S Landshamer et al.   CELL DEATH AND DIFFERENTIATION

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

(2008) Alexander Seiler et al.   Cell Metabolism

Mitochondria in Neuroplasticity and Neurological Disorders

(2008) Mark P. Mattson et al.   NEURON