Preclinical Assessment of Bacteriophage Therapy against Experimental Acinetobacter baumannii Lung Infection

Bacteriophage-resistant Acinetobacter baumannii are resensitized to antimicrobials

(2021) Fernando Gordillo Altamirano et al.   Nature Microbiology

Synergistic Killing and Re-Sensitization of Pseudomonas aeruginosa to Antibiotics by Phage-Antibiotic Combination Treatment

(2021) Emily Engeman et al.   Pharmaceuticals

Preclinical data and safety assessment of phage therapy in humans

(2021) Janet Y Nale et al.   CURRENT OPINION IN BIOTECHNOLOGY

Aminoglycosides Antagonize Bacteriophage Proliferation, Attenuating Phage Suppression of Bacterial Growth, Biofilm Formation, and Antibiotic Resistance

(2021) Pengxiao Zuo et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Phage Therapy for Multi-Drug Resistant Respiratory Tract Infections

(2021) Joshua J. Iszatt et al.   Viruses-Basel

Neutralizing Complement C5a Protects Mice with Pneumococcal Pulmonary Sepsis

(2020) Holger Müller-Redetzky et al.   ANESTHESIOLOGY

Fitness trade-offs resulting from bacteriophage resistance potentiate synergistic antibacterial strategies

(2020) Mihnea R. Mangalea et al.   INFECTION AND IMMUNITY

Standardized bacteriophage purification for personalized phage therapy

(2020) Tiffany Luong et al.   Nature Protocols

Lessons Learned From the First 10 Consecutive Cases of Intravenous Bacteriophage Therapy to Treat Multidrug-Resistant Bacterial Infections at a Single Center in the United States

(2020) Saima Aslam et al.   Open Forum Infectious Diseases

Geographical and temporal variation in the frequency and antimicrobial susceptibility of bacteria isolated from patients hospitalized with bacterial pneumonia: results from 20 years of the SENTRY Antimicrobial Surveillance Program (1997–2016)

(2019) Helio S Sader et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria

(2019) Kaitlyn E. Kortright et al.   Cell Host & Microbe

Successful adjunctive use of bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa infection in a cystic fibrosis patient

(2019) Nancy Law et al.   INFECTION

Bacteriophages Improve Outcome in Experimental Staphylococcus Aureus Ventilator Associated Pneumonia

(2019) Josef Prazak et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Phage Therapy of Pneumonia Is Not Associated with an Overstimulation of the Inflammatory Response Compared to Antibiotic Treatment in Mice

(2019) Nicolas Dufour et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Digital Image Analyses on Whole-Lung Slides in Mouse Models of Acute Pneumonia

(2018) Kristina Dietert et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Characterization of Two Novel Bacteriophages Infecting Multidrug-Resistant (MDR) Acinetobacter baumannii and Evaluation of Their Therapeutic Efficacy in Vivo

(2018) Kyoungeun Cha et al.   Frontiers in Microbiology

Phage Therapy as a Promising New Treatment for Lung Infection Caused by Carbapenem-Resistant Acinetobacter baumannii in Mice

(2018) Yunfen Hua et al.   Frontiers in Microbiology

Inhaled bacteriophage-loaded polymeric microparticles ameliorate acute lung infections

(2018) Rachit Agarwal et al.   Nature Biomedical Engineering

Phage therapy for respiratory infections

(2018) Rachel Yoon Kyung Chang et al.   ADVANCED DRUG DELIVERY REVIEWS

Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double-blind phase 1/2 trial

(2018) Patrick Jault et al.   LANCET INFECTIOUS DISEASES

Tyk2 as a target for immune regulation in human viral/bacterial pneumonia

(2017) Johanna Berg et al.   EUROPEAN RESPIRATORY JOURNAL

Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia

(2017) Kristina Dietert et al.   PLoS One

A cocktail of three virulent bacteriophages prevents Vibrio cholerae infection in animal models

(2017) Minmin Yen et al.   Nature Communications

Pro- and anti-inflammatory responses of peripheral blood mononuclear cells induced by Staphylococcus aureus and Pseudomonas aeruginosa phages

(2017) Jonas D. Van Belleghem et al.   Scientific Reports

In VivoApplication of Bacteriophage as a Potential Therapeutic Agent To Control OXA-66-Like Carbapenemase-Producing Acinetobacter baumannii Strains Belonging to Sequence Type 357

(2016) Jongsoo Jeon et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bloodstream infection caused by extensively drug-resistant Acinetobacter baumannii in cancer patients: high mortality associated with delayed treatment rather than with the degree of neutropenia

(2016) M.P. Freire et al.   CLINICAL MICROBIOLOGY AND INFECTION

Clinical and Pathophysiological Overview of Acinetobacter Infections: a Century of Challenges

(2016) Darren Wong et al.   CLINICAL MICROBIOLOGY REVIEWS

Inhaled phage therapy: a promising and challenging approach to treat bacterial respiratory infections

(2016) Elsa Bodier-Montagutelli et al.   Expert Opinion on Drug Delivery

Acinetobacter baumannii and A. pittii clinical isolates lack adherence and cytotoxicity to lung epithelial cells in vitro

(2016) María Lázaro-Díez et al.   MICROBES AND INFECTION

Oral Phage Therapy of Acute Bacterial Diarrhea With Two Coliphage Preparations: A Randomized Trial in Children From Bangladesh

(2016) Shafiqul Alam Sarker et al.   EBioMedicine

Antipseudomonal Bacteriophage Reduces Infective Burden and Inflammatory Response in Murine Lung

(2015) Rishi Pabary et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

On-Demand Isolation of Bacteriophages Against Drug-Resistant Bacteria for Personalized Phage Therapy

(2015) Sari Mattila et al.   Frontiers in Microbiology

Aerosol Phage Therapy Efficacy in Burkholderia cepacia Complex Respiratory Infections

(2014) Diana D. Semler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Burkholderia cepacia Complex Phage-Antibiotic Synergy (PAS): Antibiotics Stimulate Lytic Phage Activity

(2014) Fatima Kamal et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Viruses versus bacteria--novel approaches to phage therapy as a tool against multidrug-resistant pathogens

(2014) T. M. Viertel et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Characterization of Newly Isolated Lytic Bacteriophages Active against Acinetobacter baumannii

(2014) Maia Merabishvili et al.   PLoS One

Amplification of Aminoglycoside Resistance Gene aphA1 in Acinetobacter baumannii Results in Tobramycin Therapy Failure

(2014) P. McGann et al.   mBio

Delivery of the endolysin Cpl-1 by inhalation rescues mice with fatal pneumococcal pneumonia

(2013) J. M. Doehn et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Pulmonary drug delivery: from generating aerosols to overcoming biological barriers—therapeutic possibilities and technological challenges

(2013) Christian A Ruge et al.   Lancet Respiratory Medicine

Streptococcus pneumoniae-induced regulation of cyclooxygenase-2 in human lung tissue

(2012) Kolja V. Szymanski et al.   EUROPEAN RESPIRATORY JOURNAL

Synergistic phage-antibiotic combinations for the control ofEscherichia colibiofilmsin vitro

(2012) Elizabeth M. Ryan et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Incidence of and Risk Factors for Colistin-Associated Nephrotoxicity in a Large Academic Health System

(2011) J. M. Pogue et al.   CLINICAL INFECTIOUS DISEASES

Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo

(2011) Andre Broermann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A controlled clinical trial of a therapeutic bacteriophage preparation in chronic otitis due to antibiotic-resistantPseudomonas aeruginosa; a preliminary report of efficacy

(2009) A. Wright et al.   CLINICAL OTOLARYNGOLOGY

International Study of the Prevalence and Outcomes of Infection in Intensive Care Units

(2009) Jean-Louis Vincent   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Efficacy of Bacteriophage Therapy in a Model ofBurkholderia cenocepaciaPulmonary Infection

(2009) Lisa A. Carmody et al.   JOURNAL OF INFECTIOUS DISEASES

Toward Modern Inhalational Bacteriophage Therapy: Nebulization of Bacteriophages of Burkholderia cepacia Complex

(2008) Laleh Golshahi et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Therapeutic potential of bacteriophage in treating Klebsiella pneumoniae B5055-mediated lobar pneumonia in mice

(2008) S. Chhibber et al.   JOURNAL OF MEDICAL MICROBIOLOGY