Effects of the peripherally acting μ-opioid receptor antagonist methylnaltrexone on acute pancreatitis severity: study protocol for a multicentre double-blind randomised placebo-controlled interventional trial, the PAMORA-AP trial

Acute pancreatitis

(2020) Lotte Boxhoorn et al.   LANCET

The REDCap consortium: Building an international community of software platform partners

(2019) Paul A. Harris et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Predictors of underlying pancreatic cancer in patients with acute pancreatitis: a Danish nationwide cohort study

(2019) Jakob Kirkegård et al.   HPB

The Pancreatitis Activity Scoring System predicts clinical outcomes in acute pancreatitis: findings from a prospective cohort study

(2018) James Buxbaum et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The impact of naloxegol on anal sphincter function - Using a human experimental model of opioid-induced bowel dysfunction

(2018) Debbie Grønlund et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Impact of characteristics of organ failure and infected necrosis on mortality in necrotising pancreatitis

(2018) Nicolien J Schepers et al.   GUT

Reduction in pain: Is it worth the gain? The effect of opioids on the GI tract

(2018) J. Nee et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Colorectal Transit and Volume During Treatment With Prolonged-release Oxycodone/Naloxone Versus Oxycodone Plus Macrogol 3350

(2018) Jakob L Poulsen et al.   Journal of Neurogastroenterology and Motility

Morphine worsens the severity and prevents pancreatic regeneration in mouse models of acute pancreatitis

(2017) Usman Barlass et al.   GUT

The incidence and aetiology of acute pancreatitis across Europe

(2017) Stephen E. Roberts et al.   PANCREATOLOGY

Treatment with methylnaltrexone is associated with increased survival in patients with advanced cancer

(2016) F. Janku et al.   ANNALS OF ONCOLOGY

The complex task of measuring intestinal permeability in basic and clinical science

(2016) H. J. Galipeau et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Frequency of Progression From Acute to Chronic Pancreatitis and Risk Factors: A Meta-analysis

(2015) Sharanya J. Sankaran et al.   GASTROENTEROLOGY

Acute pancreatitis

(2015) Paul Georg Lankisch et al.   LANCET

Emerging treatments in neurogastroenterology: eluxadoline - a new therapeutic option for diarrhea-predominant IBS

(2015) B. E. Lacy   NEUROGASTROENTEROLOGY AND MOTILITY

A phase 2, double-blind, randomized, placebo-controlled, dose-escalation study to evaluate the efficacy, safety, and tolerability of naloxegol in patients with opioid-induced constipation

(2013) Lynn Webster et al.   PAIN

IAP/APA evidence-based guidelines for the management of acute pancreatitis

(2013)   PANCREATOLOGY

Morphine Induces Bacterial Translocation in Mice by Compromising Intestinal Barrier Function in a TLR-Dependent Manner

(2013) Jingjing Meng et al.   PLoS One

Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus

(2012) Peter A Banks et al.   GUT

Opioid antagonists for prevention and treatment of opioid-induced gastrointestinal effects

(2010) Peter Holzer   Current Opinion in Anesthesiology

Organ Failure and Infection of Pancreatic Necrosis as Determinants of Mortality in Patients With Acute Pancreatitis

(2010) Maxim S. Petrov et al.   GASTROENTEROLOGY

Intestinal Barrier Dysfunction in a Randomized Trial of a Specific Probiotic Composition in Acute Pancreatitis

(2009) Marc G. Besselink et al.   ANNALS OF SURGERY

Early Systemic Inflammatory Response Syndrome Is Associated With Severe Acute Pancreatitis

(2009) Vikesh K. Singh et al.   Clinical Gastroenterology and Hepatology

Derivation and validation of Spo2/Fio2 ratio to impute for Pao2/Fio2 ratio in the respiratory component of the Sequential Organ Failure Assessment score*

(2009) Pratik P. Pandharipande et al.   CRITICAL CARE MEDICINE

Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics support

(2008) Paul A. Harris et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Methylnaltrexone for Opioid-Induced Constipation in Advanced Illness

(2008) Jay Thomas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Opioid-induced immunosuppression

(2008) Paola Sacerdote   Current Opinion in Supportive and Palliative Care