The inhibition of NFкB signaling and inflammatory response as a strategy for blunting bile acid-induced hepatic and renal toxicity

Poly (ADP-Ribose) polymerase-1 (PARP-1) overactivity plays a pathogenic role in bile acids-induced nephrotoxicity in cholestatic rats

(2020) Asma Siavashpour et al.   TOXICOLOGY LETTERS

The Renaissance of Cholemic Nephropathy: A Likely Underestimated Cause of Renal Dysfunction in Liver Disease

(2019) Mattias Mandorfer et al.   HEPATOLOGY

Crosstalk network among multiple inflammatory mediators in liver fibrosis

(2019) Han-Jing Zhangdi et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Cholemic nephropathy – Historical notes and novel perspectives

(2018) Elisabeth Krones et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Dithiothreitol supplementation mitigates hepatic and renal injury in bile duct ligated mice: Potential application in the treatment of cholestasis-associated complications

(2018) Reza Heidari et al.   BIOMEDICINE & PHARMACOTHERAPY

Dual effects of sulfasalazine on rat sperm characteristics, spermatogenesis, and steroidogenesis in two experimental models

(2018) Mohammad Mehdi Ommati et al.   TOXICOLOGY LETTERS

NF-kappaB: Two Sides of the Same Coin

(2018) Bruno Pires et al.   Genes

Burden of Liver Diseases in the World

(2018) Sumeet K. Asrani et al.   JOURNAL OF HEPATOLOGY

The nephroprotective properties of taurine in colistin-treated mice is mediated through the regulation of mitochondrial function and mitigation of oxidative stress

(2018) Reza Heidari et al.   BIOMEDICINE & PHARMACOTHERAPY

Mitochondrial dysfunction as a mechanism involved in the pathogenesis of cirrhosis-associated cholemic nephropathy

(2018) Reza Heidari et al.   BIOMEDICINE & PHARMACOTHERAPY

Is immunosuppression, induced by neonatal thymectomy, compatible with poor reproductive performance in adult male rats?

(2017) M. M. Ommati et al.   Andrology

Oxidative stress influence on renal dysfunction in patients with obstructive jaundice: A case and control prospective study

(2016) David Martínez-Cecilia et al.   Redox Biology

Beyond Cox-Inhibition: ‘Side-Effects’ of Ibuprofen on Neoplastic Development and Progression

(2015) Paulo Matos et al.   CURRENT PHARMACEUTICAL DESIGN

Bile Acid-Induced Cholemic Nephropathy

(2015) Elisabeth Krones et al.   DIGESTIVE DISEASES

Enhanced anti-ulcer effect of pioglitazone on gastric ulcers in cirrhotic rats: The role of nitric oxide and IL-1β

(2014) Leila Moezi et al.   Pharmacological Reports

Bile acids in cholestasis: Bad for the liver, not so good for the kidney

(2014) Serge Erlinger   Clinics and Research in Hepatology and Gastroenterology

Cholestatic Liver Disease

(2013) Christoph Jüngst et al.   DIGESTIVE DISEASES

The burden of liver disease in Europe: A review of available epidemiological data

(2013) Martin Blachier et al.   JOURNAL OF HEPATOLOGY

Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice

(2013) Min Yang et al.   TOXICOLOGY LETTERS

Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage-mediated chronic inflammation

(2012) Yoshiaki Sunami et al.   HEPATOLOGY

Molecular targets for treatment of kidney fibrosis

(2012) Peter Y. Chuang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

New therapeutic aspect for carvedilol: Antifibrotic effects of carvedilol in chronic carbon tetrachloride-induced liver damage

(2012) Nadia Hamdy et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma

(2011) Tom Luedde et al.   Nature Reviews Gastroenterology & Hepatology

Role of nuclear factor κB in liver health and disease

(2010) Stuart M. Robinson et al.   CLINICAL SCIENCE

Pathogenesis of Cholestatic Liver Disease and Therapeutic Approaches

(2010) Gideon M. Hirschfield et al.   GASTROENTEROLOGY

Bile duct ligation in developing rats: temporal progression of liver, kidney, and brain damage

(2010) Jiunn-Ming Sheen et al.   JOURNAL OF PEDIATRIC SURGERY

Mechanistic connection between inflammation and fibrosis

(2010) Soo Bong Lee et al.   KIDNEY INTERNATIONAL

NFκB-dependent increase of kynurenine pathway activity in human placenta: Inhibition by sulfasalazine

(2010) P. Dharane (neé Ligam) et al.   PLACENTA

Oxidative Stress and the Pathogenesis of Cholestasis

(2010) Bryan Copple et al.   SEMINARS IN LIVER DISEASE

Combination therapy with andrographolide and d-penicillamine enhanced therapeutic advantage over monotherapy with d-penicillamine in attenuating fibrogenic response and cell death in the periportal zone of liver in rats during copper toxicosis

(2010) Dijendra Nath Roy et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Superoxide anion mediated mitochondrial dysfunction leads to hepatocyte apoptosis preferentially in the periportal region during copper toxicity in rats

(2009) Dijendra Nath Roy et al.   CHEMICO-BIOLOGICAL INTERACTIONS

NF-κB signaling, liver disease and hepatoprotective agents

(2008) B Sun et al.   ONCOGENE