High concentrations of ammonia induced cytotoxicity and bronchoconstriction in a precision-cut lung slices rat model

Transient receptor potential ankyrin-1 causes rapid bronchodilation via nonepithelial PGE2

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N-acetyl cysteine protects against chlorine-induced tissue damage in an ex vivo model

(2020) Lina Ågren et al.   TOXICOLOGY LETTERS

Hypersensitivity of Airway Reflexes Induced by Hydrogen Sulfide: Role of TRPA1 Receptors

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Transient receptor potential channels in pulmonary chemical injuries and as countermeasure targets

(2020) Satyanarayana Achanta et al.   ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

Ammonia exposure causes lung injuries and disturbs pulmonary circadian clock gene network in a pig study

(2020) Xiaotong Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Acute respiratory distress syndrome

(2019) Michael A. Matthay et al.   Nature Reviews Disease Primers

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

Comparisons of acute inflammatory responses of nose-only inhalation and intratracheal instillation of ammonia in rats

(2019) Linda Elfsmark et al.   INHALATION TOXICOLOGY

TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice

(2019) Zhouqing Wang et al.   Cell Death & Disease

Adverse respiratory effects in rats following inhalation exposure to ammonia: respiratory dynamics and histopathology

(2017) Michael W. Perkins et al.   INHALATION TOXICOLOGY

Precision cut lung slices as test system for candidate therapeutics in organophosphate poisoning

(2017) Julia Herbert et al.   TOXICOLOGY

Assessment of inhaled acute ammonia-induced lung injury in rats

(2016) Michael W. Perkins et al.   INHALATION TOXICOLOGY

Modulation of TRPV4 by diverse mechanisms

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Transient receptor potential cation channel, subfamily V, member 4 and airway sensory afferent activation: Role of adenosine triphosphate

(2016) Sara J. Bonvini et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transient receptor potential (TRP) channels as a therapeutic target for intervention of respiratory effects and lethality from phosgene

(2016) Devon Andres et al.   TOXICOLOGY LETTERS

A role for transient receptor potential ankyrin 1 cation channel (TRPA1) in airway hyper-responsiveness?

(2015) Aruni Jha et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury

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Release of Interleukin-1α or Interleukin-1β Depends on Mechanism of Cell Death

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Precision cut intestinal slices are an appropriate ex vivo model to study NSAID-induced intestinal toxicity in rats

(2014) Xiaoyu Niu et al.   TOXICOLOGY IN VITRO

Acute inhalation toxicity of ammonia: Revisiting the importance of RD50 and LCT01/50 relationships for setting emergency response guideline values

(2013) Jürgen Pauluhn   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Reproducible uniform equibiaxial stretch of precision-cut lung slices

(2012) N. Davidovich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Neurally Mediated Airway Constriction in Human and Other Species: A Comparative Study Using Precision-Cut Lung Slices (PCLS)

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Corticosteroid treatment inhibits airway hyperresponsiveness and lung injury in a murine model of chemical-induced airway inflammation

(2012) Elisabeth Wigenstam et al.   TOXICOLOGY

Macrophages and Tissue Injury: Agents of Defense or Destruction?

(2011) Debra L. Laskin et al.   Annual Review of Pharmacology and Toxicology

A role for sensory nerves in the late asthmatic response

(2011) Kristof Raemdonck et al.   THORAX

In vitrolung slices: a powerful approach for assessment of lung pathophysiology

(2010) Teresa A Liberati et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

N-acetylcysteine attenuates phosgene-induced acute lung injury via up-regulation of Nrf2 expression

(2010) Lin Ji et al.   INHALATION TOXICOLOGY

Electric field stimulation of precision-cut lung slices

(2010) Marco Schlepütz et al.   JOURNAL OF APPLIED PHYSIOLOGY

TRPA1 Agonists Evoke Coughing in Guinea Pig and Human Volunteers

(2009) Mark A. Birrell et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ex vivo testing of immune responses in precision-cut lung slices

(2008) M. Henjakovic et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY