Alternative animal models in predictive toxicology

Evaluation of bioconcentration and toxicity of five metals in the freshwater rotifer Euchlanis dilatata Ehrenberg, 1832

(2020) Saraí Hernández-Flores et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish

(2020) Andrew B. Hawkey et al.   NEUROTOXICOLOGY AND TERATOLOGY

Oxygen consumption rate of Caenorhabditis elegans as a high-throughput endpoint of toxicity testing using the Seahorse XFe96 Extracellular Flux Analyzer

(2020) G. Du Preez et al.   Scientific Reports

Life stage-dependent toxicities of 1-ethyl-3-methylimidazolium bromide on Caenorhabditis elegans

(2020) Hong Liu et al.   ENVIRONMENTAL POLLUTION

Requirements for Animal Experiments: Problems and Challenges

(2020) Flavia Fontana et al.   Small

High-Content and High-Throughput In Vivo Drug Screening Platforms Using Microfluidics

(2019) Adela Ben-Yakar   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Mechanisms of Engineered Nanoparticle induced Neurotoxicity in Caenorhabditis Elegans

(2019) Sotirios I. Sinis et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Using Proales similis (Rotifera) for toxicity assessment in marine waters

(2019) Terry W. Snell et al.   ENVIRONMENTAL TOXICOLOGY

Intergenerational reproductive toxicity of chlordecone in male Caenorhabditis elegans

(2019) Shuhao Dai et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Two-generational effects and recovery of arsenic and arsenate on Daphnia magna in the presence of nano-TiO2

(2019) Wenhong Fan et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Deriving site-specific water quality criteria for ammonia from national versus international toxicity data

(2019) Zhihong Liu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

A review of toxicity induced by persistent organic pollutants (POPs) and endocrine-disrupting chemicals (EDCs) in the nematode Caenorhabditis elegans

(2019) Haibo Chen et al.   JOURNAL OF ENVIRONMENTAL MANAGEMENT

In silico prediction of MicroRNA role in regulation of Zebrafish (Danio rerio) responses to nanoparticle exposure

(2019) Moyan Hu et al.   TOXICOLOGY IN VITRO

Caenorhabditis elegans as a tool for environmental risk assessment: emerging and promising applications for a “nobelized worm”

(2019) L. Queirós et al.   CRITICAL REVIEWS IN TOXICOLOGY

Increased sensitivity of subantarctic marine invertebrates to copper under a changing climate - Effects of salinity and temperature

(2019) Jessica R. Holan et al.   ENVIRONMENTAL POLLUTION

Genotoxic Response and Mortality in Three Marine Copepods Exposed to Waterborne Copper

(2019) Andrea Sahlmann et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Effect of biosurfactant derived from Vibrio natriegens MK3 against Vibrio harveyi biofilm and virulence

(2019) Suganya Kannan et al.   JOURNAL OF BASIC MICROBIOLOGY

Toxicity of lead and mancozeb differs in two monophyletic Daphnia species

(2019) G.S. Araujo et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Use of scanning and image recognition technology to semi-automate larval development assessment in toxicity tests with a tropical copepod

(2019) Monique T. Binet et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Use of Zebrafish in Drug Discovery Toxicology

(2019) Steven Cassar et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Chronic exposure to environmental concentrations of phenanthrene impairs zebrafish reproduction

(2019) Xiandong Peng et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Monobutyl phthalate (MBP) can dysregulate the antioxidant system and induce apoptosis of zebrafish liver

(2019) Yaqi Jiao et al.   ENVIRONMENTAL POLLUTION

Toxicity Assessment of Herbal Medicine Using Zebrafish Embryos: A Systematic Review

(2019) Chanika D. Jayasinghe et al.   Evidence-based Complementary and Alternative Medicine

“Zebrafish as an animal model for food safety research: trends in the animal research”

(2019) Ricardo Lacava Bailone et al.   FOOD BIOTECHNOLOGY

Evaluation of the toxicity potential of acute and sub-acute exposure to the aqueous root extract of Aristolochia ringens Vahl. (Aristolochiaceae)

(2019) Flora R. Aigbe et al.   JOURNAL OF ETHNOPHARMACOLOGY

Early-life long-term exposure to ZnO nanoparticles suppresses innate immunity regulated by SKN-1/Nrf and the p38 MAPK signaling pathway in Caenorhabditis elegans

(2019) Shang-Wei Li et al.   ENVIRONMENTAL POLLUTION

Toxicological study of metal and metal oxide nanoparticles in zebrafish

(2019) Changcun Bai et al.   JOURNAL OF APPLIED TOXICOLOGY

Embryo bioassays with aquatic animals for toxicity testing and hazard assessment of emerging pollutants: A review

(2019) Ricardo Capela et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Systemic toxicity evaluation of novel tobacco products in Caenorhabditis elegans

(2019) Haiqing Cai et al.   TOXICOLOGY IN VITRO

Toxicity assessment of parabens in Caenorhabditis elegans

(2019) Yogendra Nagar et al.   CHEMOSPHERE

Toxicogenomic responses of low level anticancer drug exposures in Daphnia magna

(2018) Chiara Russo et al.   AQUATIC TOXICOLOGY

A test battery for assessing the ecotoxic effects of textile dyes

(2018) Gisele Augusto Rodrigues de Oliveira et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cytotoxicity and histopathological analysis of titanium nanoparticles via Artemia salina

(2018) Supicha Kachenton et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Acute Toxicity of Sodium Chloride and Potassium Chloride to a Unionid Mussel (Lampsilis siliquoidea ) in Water Exposures

(2018) Ning Wang et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Is it Fish Embryo Test (FET) According to OECD 236 Sensible Enough for Delivering Quality Data for Effluent Risk Assessment?

(2018) Julio Alberto Alegre Stelzer et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Nanoecotoxicity assessment of graphene oxide and its relationship with humic acid

(2018) Vera L. Castro et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Acrylamide acute neurotoxicity in adult zebrafish

(2018) Melissa Faria et al.   Scientific Reports

Biocompatible fluorescent carbon quantum dots prepared from beetroot extract for in vivo live imaging in C. elegans and BALB/c mice

(2018) Vikram Singh et al.   Journal of Materials Chemistry B

Introducing a new standardized nanomaterial environmental toxicity screening testing procedure, ISO/TS 20787: aquatic toxicity assessment of manufactured nanomaterials in saltwater Lakes using Artemia sp. nauplii

(2018) Seyed Ali Johari et al.   TOXICOLOGY MECHANISMS AND METHODS

Environmental characterization of 4,4′-dichlorobenzophenone in surface waters from Macao and Hong Kong coastal areas (Pearl River Delta) and its toxicity on two biological models: Artemia salina and Daphnia magna

(2018) Lucia Ivorra et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Whole-Life-Stage Characterization in the Basic Biology of Daphnia magna and Effects of TDCIPP on Growth, Reproduction, Survival, and Transcription of Genes

(2017) Han Li et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Toxicity studies of six types of carbon nanoparticles in a chicken-embryo model

(2017) Natalia Kurantowicz et al.   International Journal of Nanomedicine

Bioassays with freshwater snails Biomphalaria sp.: from control of hosts in public health to alternative tools in ecotoxicology

(2017) Eduardo Cyrino Oliveira-Filho et al.   INVERTEBRATE REPRODUCTION & DEVELOPMENT

Larvicidal, Histopathological Efficacy of Penicillium daleae against Larvae of Culex quinquefasciatus and Aedes aegypti Plus Biotoxicity on Artemia nauplii a Non-target Aquatic Organism

(2017) C. Ragavendran et al.   Frontiers in Pharmacology

Short-term exposure with high concentrations of pristine microplastic particles leads to immobilisation of Daphnia magna

(2016) Saskia Rehse et al.   CHEMOSPHERE

Full life-cycle toxicity assessment on triclosan using rotifer Brachionus calyciflorus

(2016) Lilan Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

A case study to optimise and validate the brine shrimp Artemia franciscana immobilisation assay with silver nanoparticles: The role of harmonisation

(2016) Monika Kos et al.   ENVIRONMENTAL POLLUTION

Effect of age on acute toxicity of cadmium, copper, nickel, and zinc in individual-metal exposures toDaphnia magnaneonates

(2016) Elizabeth M. Traudt et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Acute sensitivity of a broad range of freshwater mussels to chemicals with different modes of toxic action

(2016) Ning Wang et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

TheC. elegansmodel in toxicity testing

(2016) Piper Reid Hunt   JOURNAL OF APPLIED TOXICOLOGY

The chick embryo chorioallantoic membrane (CAM). A multifaceted experimental model

(2016) Domenico Ribatti   MECHANISMS OF DEVELOPMENT

Alternative Animal and Non-Animal Models for Drug Discovery and Development: Bonus or Burden?

(2016) Irlan Almeida Freires et al.   PHARMACEUTICAL RESEARCH

Lethal and Sublethal Toxicity Comparison of BFRs to Three Marine Planktonic Copepods: Effects on Survival, Metabolism and Ingestion

(2016) Wenjing Gong et al.   PLoS One

Relating suborganismal processes to ecotoxicological and population level endpoints using a bioenergetic model

(2015) Bharath Ananthasubramaniam et al.   ECOLOGICAL APPLICATIONS

Body size-dependent toxicokinetics and toxicodynamics could explain intra- and interspecies variability in sensitivity

(2015) André Gergs et al.   ENVIRONMENTAL POLLUTION

The Impact of Polystyrene Microplastics on Feeding, Function and Fecundity in the Marine Copepod Calanus helgolandicus

(2015) Matthew Cole et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Assessing toxicity of copper nanoparticles across five cladoceran species

(2015) Lan Song et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Chick embryo chorioallantoic membrane (CAM): an alternative predictive model in acute toxicological studies for anti-cancer drugs

(2015) Chin Siang KUE et al.   EXPERIMENTAL ANIMALS

Comparison of toxicity values across zebrafish early life stages and mammalian studies: Implications for chemical testing

(2015) Nicole A. Ducharme et al.   REPRODUCTIVE TOXICOLOGY

Alternatives to animal testing: A review

(2015) Sonali K. Doke et al.   SAUDI PHARMACEUTICAL JOURNAL

The chicken chorioallantoic membrane model in biology, medicine and bioengineering

(2014) Patrycja Nowak-Sliwinska et al.   ANGIOGENESIS

Temperature-dependent toxicities of four common chemical pollutants to the marine medaka fish, copepod and rotifer

(2014) Adela J. Li et al.   ECOTOXICOLOGY

Developmental toxicity, acute toxicity and mutagenicity testing in freshwater snails Biomphalaria glabrata (Mollusca: Gastropoda) exposed to chromium and water samples

(2014) Lenita de Freitas Tallarico et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Bacterial virulence analysis using brine shrimp as an infection model in relation to the importance of quorum sensing and proteases

(2014) Mi-Nan Lee et al.   JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY

A novel model of early development in the brine shrimp,Artemia franciscana, and its use in assessing the effects of environmental variables on development, emergence, and hatching

(2014) Courtney H. Neumeyer et al.   JOURNAL OF MORPHOLOGY

Acute toxicity testing with the tropical marine copepod Acartia sinjiensis: Optimisation and application

(2013) F. Gissi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Evaluation of alpha and gamma aluminum oxide nanoparticle accumulation, toxicity, and depuration inArtemia salinalarvae

(2013) Mehmet Ates et al.   ENVIRONMENTAL TOXICOLOGY

The effects of salinity exposure on multiple life stages of a common freshwater mussel,Elliptio complanata

(2013) Carrie J. Blakeslee et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Systematic Reviews of Animal Models: Methodology versus Epistemology

(2013) Ray Greek et al.   International Journal of Medical Sciences

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

Mortality, bioaccumulation and physiological responses in juvenile freshwater mussels (Lampsilis siliquoidea) chronically exposed to copper

(2012) Marianna B. Jorge et al.   AQUATIC TOXICOLOGY

Interlaboratory comparison of a standardized toxicity test using the nematode Caenorhabditis elegans (ISO 10872)

(2012) Sebastian Höss et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Standardized methods for acute and semichronic toxicity tests with the copepod Acartia tonsa

(2012) Gessica Gorbi et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Toxicity of Metals to a Freshwater Snail,Melanoides tuberculata

(2012) M. Shuhaimi-Othman et al.   TheScientificWorldJOURNAL

Toxicity of Cadmium, Lead, Mercury and Methyl Parathion on Euchlanis dilatata Ehrenberg 1832 (Rotifera: Monogononta)

(2011) Juan Carlos Arias-Almeida et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Bivalve molluscs as a unique target group for nanoparticle toxicity

(2011) Laura Canesi et al.   MARINE ENVIRONMENTAL RESEARCH

Ecotoxicology, ecophysiology, and mechanistic studies with rotifers

(2010) Hans-U. Dahms et al.   AQUATIC TOXICOLOGY

Acute and Chronic Toxicity of Copper to the Euryhaline Rotifer, Brachionus plicatilis (“L” Strain)

(2010) W. R. Arnold et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

High-throughput screening and small animal models, where are we?

(2010) Jean Giacomotto et al.   BRITISH JOURNAL OF PHARMACOLOGY

Bioaccumulation and toxic effects of cadmium on feeding and growth of an Indian pond snail Lymnaea luteola L. under laboratory conditions

(2010) Sangita Das et al.   JOURNAL OF HAZARDOUS MATERIALS

Bioaccumulation of copper and toxic effects on feeding, growth, fecundity and development of pond snail Lymnaea luteola L.

(2010) Sangita Das et al.   JOURNAL OF HAZARDOUS MATERIALS

A comparative study of toxicity identification using Daphnia magna and Tigriopus japonicus: Implications of establishing effluent discharge limits in Korea

(2010) Sung-Wook Kang et al.   MARINE POLLUTION BULLETIN

A Critical Review: 2,3,7,8 –Tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) Effects on Gonad Development in Bivalve Mollusks

(2009) KEITH R. COOPER et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

Review on the acuteDaphnia magnatoxicity test – Evaluation of the sensitivity and the precision of assays performed with organisms from laboratory cultures or hatched from dormant eggs

(2009) G. Persoone et al.   Knowledge and Management of Aquatic Ecosystems

Brine shrimp bioassay: Importance of correct taxonomic identification ofArtemia(Anostraca) species

(2008) David R. Ruebhart et al.   ENVIRONMENTAL TOXICOLOGY

Toxicity Testing of Restorative Dental Materials Using Brine Shrimp Larvae (Artemia salina)

(2008) Manar M. Milhem et al.   Journal of Applied Oral Science

Utility of Caenorhabditis elegans in high throughput neurotoxicological research

(2008) Kirsten J. Helmcke et al.   NEUROTOXICOLOGY AND TERATOLOGY