Article
Chemistry, Multidisciplinary
Zhanlin Zhang, Hui Yan, Bo Qiu, Pan Ran, Wenxiong Cao, Xinwei Jia, Kun Huang, Xiaohong Li
Summary: In this study, a therapeutic strategy was developed to integrate real-time optical imaging and simultaneous photodynamic therapy (PDT) of bacterial infections into persistent luminescence (PL) nanoparticles (NPs). The strategy enables precise imaging and non-antibiotic treatment of bacterial infections without causing side effects to normal tissues.
Article
Nanoscience & Nanotechnology
Rui Zou, Yifan Gao, Yong Zhang, Ju Jiao, Ka-Leung Wong, Jing Wang
Summary: This study developed multifunctional hybrid mesoporous nanoparticles that integrate near-infrared persistent luminescence nanoparticles, magnetic nanoparticles, and radionuclides, showing great potential for cancer therapy and diagnosis through imaging and treatment.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Review
Nanoscience & Nanotechnology
Aurelie Bessiere, Jean-Olivier Durand, Camille Nous
Summary: PerL materials, in the form of nanoparticles, have shown great potential as bio-nanoprobes for in vivo small animal imaging and photodynamic therapy in deep-seated tissues. The physical association and targeting ability of PerL materials and photosensitizers, as well as the versatility in excitation protocols, play important roles in their successful application.
Review
Medicine, Research & Experimental
Paromita Sarbadhikary, Blassan P. George, Heidi Abrahamse
Summary: Photodynamic Therapy (PDT) has emerged as a promising alternative in cancer diagnosis and treatment, utilizing light-induced activation of photosensitizers to kill cancer cells. PDT offers advantages such as minimal invasiveness and spatio-temporal control, with proper planning of parameters being crucial for efficacy. The design of PS formulations for imaging-guided PDT has shown promising potential, with recent advances in activatable phototheranostic agents enhancing the specificity of treatment.
Article
Chemistry, Multidisciplinary
Xiaokun Zheng, Wenbo Wu, Yue Zheng, Yiwen Ding, Yu Xiang, Bin Liu, Aijun Tong
Summary: This study utilized organic nanoparticles (ONPs) for afterglow imaging-guided photodynamic therapy (PDT), achieving high SBR and good tissue penetration for effective tumor growth suppression in mice with minimal damage to major organs.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Haoran Chen, Fengxia Wu, Xiaoyu Xie, Wang Wang, Qiqing Li, Langping Tu, Bin Li, Xianggui Kong, Yulei Chang
Summary: The study developed a theranostic nanoplatform that combines treatment and diagnosis functions through photoswitchable lanthanide-doped nanoparticles to achieve real-time imaging and PDT/chemotherapy treatment. Furthermore, the incorporation of additional functionalities enhanced the therapeutic effect, indicating potential application value in tumor treatment.
Review
Chemistry, Inorganic & Nuclear
Carlos F. G. C. Geraldes, M. Margarida C. A. Castro, Joop A. Peters
Summary: Mn(III) porphyrins show great potential as Gd-free MRI contrast agents due to their interesting redox properties and high affinity for tumor tissues. With applications in photothermal, photodynamic, and sonodynamic therapies, they are attractive for theranostics development. Their relative longitudinal relaxivity at typical clinical MRI field strengths is even higher than traditional Gd-based agents.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Xu Zhao, Kai-Chao Zhao, Li-Jian Chen, Yu-Shi Liu, Jia-Lin Liu, Xiu-Ping Yan
Summary: This study presents a design of an acid-activated and continuous external irradiation-free photothermal and photodynamic synchronous theranostic nanoplatform for precision tumor-targeting near-infrared image-guided therapy. The platform offers advantages of reversible activation, synergistic enhancement, tumor targetability, and continuous external irradiation-free properties.
Article
Engineering, Biomedical
Qiang Wang, Nian Liu, Zhenyu Hou, Junpeng Shi, Xinhui Su, Xiaolian Sun
Summary: A novel I-131 labeled nanoplatform with Cerenkov radiation capability was developed for radiotherapy and radiation-induced photodynamic therapy, showing excellent tumor inhibition in both in vitro and in vivo models. The combination of self-activated PDT and RT has the potential to greatly benefit deep tumor therapy.
ADVANCED HEALTHCARE MATERIALS
(2021)
Review
Pharmacology & Pharmacy
Rajkumar Sekar, Nagaraj Basavegowda, Saktishree Jena, Santhoshkumar Jayakodi, Pandian Elumalai, Amballa Chaitanyakumar, Prathap Somu, Kwang-Hyun Baek
Summary: This review discusses the recent developments in doped CNDs for cancer therapy, including their preparations, properties, imaging, and therapeutic applications.
Article
Chemistry, Physical
Bei-Bei Wang, Li-Xia Yan, Li-Jian Chen, Xu Zhao, Xiu-Ping Yan
Summary: This study reports a multifunctional nanoplatform that can effectively kill bacteria and provide high-sensitive persistent luminescence turn-on imaging by triggering the bacterial microenvironment. The platform enables accurate targeting, high sensitivity imaging, synergistic therapy, and on-demand drug release for multidrug-resistant bacterial infections.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Yize Zhang, Junjun Wang, Shen Wang, Xiaojiao Zhu, Zhipeng Yu, Zhichao Wu, Jianhua Yu, Hongping Zhou
Summary: The strategy of planarization and donor rotation was applied to design a series of D-pi-A systems, optimizing intramolecular charge transfer and non-radiative transitions to enhance photoacoustic and photothermal properties and improve ICT effect for multi-modal imaging-guided therapy in vivo.
MATERIALS CHEMISTRY FRONTIERS
(2022)
Article
Biophysics
Na An, Yao Zhang, Han Sheng Lu, Shuang Long Tang, Yan Gao, Xiao Hui Li, Chong Shen Guo
Summary: This study established a cancer theranostic method by using laser-induced breakdown spectroscopy (LIBS)-mediated synergistic photothermal/photodynamic therapy. PEGylated cobalt phosphate nanoparticles with strong near-infrared absorbance, high photothermal conversion efficiency, and reactive oxygen species generation effect were used for tumor localization and treatment. The LIBS imaging system provided fast, real-time analysis and imaging, facilitating precise tumor treatment by monitoring the distribution of nanoparticles.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Yahua Liu, Fengye Mo, Jialing Hu, Qunying Jiang, Xiuyuan Wang, Zhiqiao Zou, Xian-Zheng Zhang, Dai-Wen Pang, Xiaoqing Liu
Summary: This study developed a tumor microenvironment-activated photothermal and photoacoustic agent for precise cancer diagnosis and treatment. Controllable plasmonic heating enables therapy and imaging in tumor tissues while avoiding damage to normal tissues.
Article
Materials Science, Biomaterials
Gang Shu, Huaixin Zhao, Xuening Zhang
Summary: Molecular imaging-guided therapy is essential for precise cancer intervention, but designing an imaging platform for autofluorescence-free dual-modal imaging-guided drug delivery remains a challenge. In this study, a persistent luminescent metal-organic framework (PLNPs@MIL-100(Fe)) was prepared for dual-modal imaging-guided drug delivery. The PLNPs@MIL-100(Fe) exhibited near-infrared persistent luminescence and T-2-weighted signal, enabling precise in vivo dual-modal imaging of tumor-bearing mice. The porous MIL-100(Fe) shell provided high drug loading capacity and acid-triggered drug release for drug delivery.
BIOMATERIALS SCIENCE
(2023)
Review
Chemistry, Analytical
Shu-Ting Xu, Xiu-Ping Yan, Hai-Long Qian
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Applied
Jing-Xuan Guo, Lu-Ming Pan, Meng-Chao Wang, Li-Jian Chen, Xu Zhao
Summary: Here, we reported a ratiometric aptasensor based on dual-colored persistent luminescent nanoparticles for accurate detection of ochratoxin A (OTA), which was free from exogenous interference and autofluorescence. The developed aptasensor showed a low detection limit of 3.4 pg mL-1, wide linearity in the range of 0.01-50 ng mL-1, and high precision of 3.1%. It was successfully applied for the analysis of OTA in grain samples with recoveries of 97.6%-105.2%.
Article
Engineering, Chemical
Hao-Ze Li, Cheng Yang, Hai-Long Qian, Xiu-Ping Yan
Summary: The excessive use of diclofenac sodium has caused environmental and food safety problems. Ionic covalent organic frameworks (iCOFs) are effective adsorbents, but conventional synthesis methods are limited by high temperature and long reaction time. This study presents a room-temperature strategy for synthesizing iCOFs in 24 hours, which showed better performance than those synthesized at high temperature. The synthesized iCOFs exhibited high adsorption capacity and efficiency for diclofenac sodium, making it a promising method for pollutant removal.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Jiancheng Dong, Yidong Peng, Dan Wang, Le Li, Chao Zhang, Feili Lai, Guanjie He, Xu Zhao, Xiu-Ping Yan, Piming Ma, Johan Hofkens, Yunpeng Huang, Tianxi Liu
Summary: In this study, a hierarchical nonwoven electronic textile (E-textile) is developed by imitating the transpiration system of plants and the water diode phenomenon. The E-textile exhibits unidirectional water transport, excellent mechanical matching, and reversible color-switching ability. As an on-skin bioelectrode, it demonstrates accurate and stable detection of biomechanical and bioelectrical signals, and can be applied in human-machine interfaces for gesture control and smart alarms. This hierarchically-designed E-textile offers a practical and innovative method for designing comfortable and daily applicable on-skin electronics.
Article
Chemistry, Physical
Le Li, Jian Meng, Xuran Bao, Yunpeng Huang, Xiu-Ping Yan, Hai-Long Qian, Chao Zhang, Tianxi Liu
Summary: A direct ink writing 3D printing approach was used to prepare all-printed flexible micro-supercapacitors using rationally designed PEDOT:PSS/MXene composite gels as inks. The MXene nanosheets in the printable inks can enhance the printability of PEDOT:PSS solution and modulate the electronic structures of PEDOT:PSS during a structure transition. The resulting 3D printed micro-supercapacitors and integrated devices exhibit large capacitances, excellent rate performance, and high cycling stability even under exceptional deformations and low temperatures.
ADVANCED ENERGY MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Li-Ya Wang, Li-Jian Chen, Xu Zhao, Yan Lv, Tianxi Liu, Xiu-Ping Yan
Summary: The researchers report an activatable antimicrobial nanoplatform with ultralow-background persistent luminescent (PL) turn-on imaging and therapeutic capability. The platform utilizes chitosan as a linker to immobilize copper ions on the surface of persistent luminescent nanoparticles (PLNPs) to fabricate PLNPs-CS-Cu2+. The PL emission of PLNPs is quenched by Cu2+ under physiological conditions but recovered due to the conversion of Cu2+ into Cu+ by high glutathione (GSH) levels at the infection site. The as-prepared antibacterial nanoplatform shows promise for highly sensitive persistent luminescent imaging and simultaneous treatment of bacterial infection.
ACS APPLIED NANO MATERIALS
(2023)
Article
Engineering, Environmental
Yaqiang Duan, Pengwu Xu, Tianxi Liu, Zicheng Wang, Xiuping Yan, Weijun Yang, Deyu Niu, Piming Ma
Summary: Designing a sandwich-like heterostructure of PDMS/SiO2@MXene composites with a floatable interlayer was achieved by regulating the affinity of mixed solvents and SiO2@MXene. The composites exhibited superior EMI shielding effectiveness, stable mechanical property, and wide temperature window in application.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Applied
Jiang-Yue Wang, Li-Jian Chen, Xu Zhao, Xiu-Ping Yan
Summary: A pH-responsive colorimetric microneedle (MN) patch made from bromothymol blue (BTB) and silk fibroin meth acryloyl (SilMA) was developed for sensing salmon spoilage. The MN patch could extract tissue fluids from salmon and display color changes based on the pH variation caused by the increase of total volatile basic nitrogen. This method allows rapid determination of salmon spoilage and can be analyzed nondestructively on a smartphone.
Article
Chemistry, Physical
Jiancheng Dong, Xinwei Tang, Yidong Peng, Chonghui Fan, Le Li, Chao Zhang, Feili Lai, Guanjie He, Piming Ma, Zicheng Wang, Qufu Wei, Xiu-Ping Yan, Hai-Long Qian, Yunpeng Huang, Tianxi Liu
Summary: In this study, highly breathable and ultrastretchable SEBS-Ag-liquid metal (SSLM) nonwoven electronic textiles were fabricated for versatile applications in wearable and healthcare electronics. The SSLM E-textiles demonstrated exceptional EMI shielding effectiveness and efficient Joule heating performance under large-scale deformation. Moreover, they showed prominent monitoring performance for various biophysical signals and electroencephalogram signals. Therefore, the liquid metal E-textiles have great potential in next-generation skin electronics and protective textiles.
Article
Nanoscience & Nanotechnology
Tian-Tian Ma, Cheng Yang, Hai-Long Qian, Piming Ma, Tianxi Liu, Xiu-Ping Yan
Summary: The development of novel functional materials for the effective separation of isomers is important in various fields. The fabrication of a trifluoromethyl-functionalized 2D COF, TpTFMB, was reported for isomer separation. TpTFMB exhibited various functions such as hydrogen bonding, dipole interaction, and steric effect, enabling the high-resolution separation of different types of isomers. This work provides a new strategy for designing efficient isomer separation materials.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Engineering, Manufacturing
Minhao Guo, Yufan Zhang, Chun Huang, Xu Zhao, Xiu-Ping Yan, Yunpeng Huang, Le Li, Tianxi Liu
Summary: This study successfully developed a novel shape memory polyimide aerogel composite with a high programming temperature and excellent shape recovery capability. By regulating molecular interactions and pore structures, the desired thermo-mechanical performances were achieved, showing great potential for widespread applications in harsh environments.
COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
(2023)
Article
Chemistry, Applied
Qing Huang, Lixia Yan, Haodong Wei, Xingjian Ye, Wenlong Wang, Cheng Yang, Xiu-Ping Yan, Yi Zhang
Summary: Heat treatment and the use of additives in food processing can introduce nanomaterials, which have raised concerns due to the lack of toxicological investigation and market standards. This study focused on the structural properties and cytotoxicity of fluorescent carbon nanoparticles (FCNPs) in fried bamboo charcoal peanuts. It was found that FCNPs extracted from charcoal shells and peanut kernels had different particle sizes and water solubility properties. Furthermore, the cellular endocytosis and toxic effects of FCNPs were explored, with charcoal-shell FCNPs showing slightly higher toxicity compared to peanut kernel FCNPs.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Engineering, Environmental
Li-Hong Su, Hai -Long Qian, Cheng Yang, Chuanxi Wang, Zhenyu Wang, Xiu- Ping Yan
Summary: This study presents a facile surface imprinting approach using dopamine to generate imprinted cavities on the surface of irreversible COF for efficient extraction of fluoroquinolones (FQs) in food samples. The resulting MI-COF exhibited exceptional adsorption capacity, with a 2.2-fold enhancement compared to nonimprinted COF. Furthermore, MI-COF was successfully employed as an adsorbent coupled with HPLC for the simultaneous determination of enrofloxacin, norfloxacin, and ciprofloxacin, showing low limits of detection, high precision, and satisfactory recoveries in food samples.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Wen-Chao Deng, Hai-Long Qian, Cheng Yang, Shu-Ting Xu, Xiu-Ping Yan
Summary: Covalent organic frameworks (COFs) are promising as stationary phases for gas chromatography (GC). In this study, a two-step method was developed to fabricate COF-bound capillary columns with high uniformity and crystallinity. The fabricated Tab-DHTA-bound capillary column showed better separation performance for isomers compared to commercial columns DB-5 and HP-FFAP.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Materials Science, Biomaterials
Jing-Xuan Guo, Xue-Mei Gao, Tian-Yue Gu, Hao-Ze Li, Li-Jian Chen, Xu Zhao, Xiu-Ping Yan
Summary: A porphyrin-anthracene covalent organic framework (Por-DPA) was fabricated for sustainable photosterilization and bacterial-infected wound healing. Por-DPA exhibited good photothermal conversion performance and efficient 1O2 production capacity, preventing self-aggregation quenching and thermal damage, and promoting wound healing without obvious side effects.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).