Systems approach reveals distinct and shared signaling networks of the four PGE 2 receptors in T cells
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Title
Systems approach reveals distinct and shared signaling networks of the four PGE
2
receptors in T cells
Authors
Keywords
-
Journal
Science Signaling
Volume 14, Issue 703, Pages -
Publisher
American Association for the Advancement of Science (AAAS)
Online
2021-10-16
DOI
10.1126/scisignal.abc8579
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Note: Only part of the references are listed.- Illuminating the dark phosphoproteome
- (2019) Elise J. Needham et al. Science Signaling
- T cell–intrinsic prostaglandin E 2 -EP2/EP4 signaling is critical in pathogenic T H 17 cell–driven inflammation
- (2018) Jinju Lee et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Protein Kinase CK2: An Emerging Regulator of Immunity
- (2018) Sara A. Gibson et al. TRENDS IN IMMUNOLOGY
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- (2017) Praneeth Siripurapu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- G Protein–Coupled Receptor Signaling Through β-Arrestin–Dependent Mechanisms
- (2017) Pierre-Yves Jean-Charles et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- The Diverse Roles of Arrestin Scaffolds in G Protein–Coupled Receptor Signaling
- (2017) Yuri K. Peterson et al. PHARMACOLOGICAL REVIEWS
- Analyses of PDE-regulated phosphoproteomes reveal unique and specific cAMP-signaling modules in T cells
- (2017) Michael-Claude G. Beltejar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lighting Up T Lymphocyte Signaling with Quantitative Phosphoproteomics
- (2017) Candelas Álvarez-Salamero et al. Frontiers in Immunology
- Aspirin As Secondary Prevention in Patients With Colorectal Cancer: An Unselected Population-Based Study
- (2016) Simer J. Bains et al. JOURNAL OF CLINICAL ONCOLOGY
- OmniPath: guidelines and gateway for literature-curated signaling pathway resources
- (2016) Dénes Türei et al. NATURE METHODS
- The Perseus computational platform for comprehensive analysis of (prote)omics data
- (2016) Stefka Tyanova et al. NATURE METHODS
- The Role of Prostaglandin E 2 in Tumor-Associated Immunosuppression
- (2016) Dingzhi Wang et al. TRENDS IN MOLECULAR MEDICINE
- Prioritizing functional phosphorylation sites based on multiple feature integration
- (2016) Qingyu Xiao et al. Scientific Reports
- Augmentation of CAR T-cell Trafficking and Antitumor Efficacy by Blocking Protein Kinase A Localization
- (2016) K. Newick et al. Cancer Immunology Research
- Phosphoproteomics in the Age of Rapid and Deep Proteome Profiling
- (2015) Nicholas M. Riley et al. ANALYTICAL CHEMISTRY
- Prostaglandin E2 and the EP receptors in malignancy: possible therapeutic targets?
- (2015) G O'Callaghan et al. BRITISH JOURNAL OF PHARMACOLOGY
- Immunosuppression associated with chronic inflammation in the tumor microenvironment
- (2015) Dingzhi Wang et al. CARCINOGENESIS
- Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity
- (2015) Santiago Zelenay et al. CELL
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- (2015) MINGZHAN DU et al. ONCOLOGY REPORTS
- Ndrg1 is a T-cell clonal anergy factor negatively regulated by CD28 costimulation and interleukin-2
- (2015) Yu Mi Oh et al. Nature Communications
- Large-scale models of signal propagation in human cells derived from discovery phosphoproteomic data
- (2015) Camille D. A. Terfve et al. Nature Communications
- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
- Estimates of benefits and harms of prophylactic use of aspirin in the general population
- (2014) J. Cuzick et al. ANNALS OF ONCOLOGY
- A Chemical Biology Approach Demonstrates G Protein βγ Subunits Are Sufficient to Mediate Directional Neutrophil Chemotaxis
- (2014) Chinmay R. Surve et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Quantitative Phosphoproteomic Analysis of Signaling Downstream of the Prostaglandin E2/G-Protein Coupled Receptor in Human Synovial Fibroblasts: Potential Antifibrotic Networks
- (2014) Casimiro Gerarduzzi et al. JOURNAL OF PROTEOME RESEARCH
- Single-step Enrichment by Ti4+-IMAC and Label-free Quantitation Enables In-depth Monitoring of Phosphorylation Dynamics with High Reproducibility and Temporal Resolution
- (2014) Erik L. de Graaf et al. MOLECULAR & CELLULAR PROTEOMICS
- KinomeXplorer: an integrated platform for kinome biology studies
- (2014) Heiko Horn et al. NATURE METHODS
- Prostaglandin E2 receptor EP2 mediates Snail expression in hepatocellular carcinoma cells
- (2014) SHAN-YU CHENG et al. ONCOLOGY REPORTS
- An Inflammatory Mediator, Prostaglandin E2, in Colorectal Cancer
- (2013) Dingzhi Wang et al. CANCER JOURNAL
- Prostaglandin E2 promotes hepatocellular carcinoma cell invasion through upregulation of YB-1 protein expression
- (2013) HAI ZHANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Increased Th17 Cells in the Tumor Microenvironment Is Mediated by IL-23 via Tumor-Secreted Prostaglandin E2
- (2013) X. Qian et al. JOURNAL OF IMMUNOLOGY
- Interrogating cAMP-dependent Kinase Signaling in Jurkat T Cells via a Protein Kinase A Targeted Immune-precipitation Phosphoproteomics Approach
- (2013) Piero Giansanti et al. MOLECULAR & CELLULAR PROTEOMICS
- Robust phosphoproteome enrichment using monodisperse microsphere–based immobilized titanium (IV) ion affinity chromatography
- (2013) Houjiang Zhou et al. Nature Protocols
- Proinflammatory and Immunoregulatory Roles of Eicosanoids in T Cells
- (2013) Anna Mari Lone et al. Frontiers in Immunology
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- (2012) Anna Sawicka et al. BIOCHIMIE
- Modulation of Host Natural Killer Cell Functions in Breast Cancer via Prostaglandin E2 Receptors EP2 and EP4
- (2012) Dawn M. Holt et al. JOURNAL OF IMMUNOTHERAPY
- Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials
- (2012) Peter M Rothwell et al. LANCET
- The Proteomics Identifications (PRIDE) database and associated tools: status in 2013
- (2012) Juan Antonio Vizcaíno et al. NUCLEIC ACIDS RESEARCH
- Modulation of T cell immune functions by the prostaglandin E2 - cAMP pathway in chronic inflammatory states
- (2011) Kristoffer Watten Brudvik et al. BRITISH JOURNAL OF PHARMACOLOGY
- Regulatory T-cell-mediated inhibition of antitumor immune responses is associated with clinical outcome in patients with liver metastasis from colorectal cancer
- (2011) Kristoffer Watten Brudvik et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
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- (2011) M. Nakanishi et al. Cancer Prevention Research
- Prostaglandin E2 and T cells: friends or foes?
- (2011) Vinatha Sreeramkumar et al. IMMUNOLOGY AND CELL BIOLOGY
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- (2011) R. Mosenden et al. JOURNAL OF IMMUNOLOGY
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- (2011) Christian K. Frese et al. JOURNAL OF PROTEOME RESEARCH
- Protein kinase A antagonist inhibits β-catenin nuclear translocation, c-Myc and COX-2 expression and tumor promotion in ApcMin/+ mice
- (2011) Kristoffer W Brudvik et al. Molecular Cancer
- International Union of Basic and Clinical Pharmacology. LXXXIII: Classification of Prostanoid Receptors, Updating 15 Years of Progress
- (2011) D. F. Woodward et al. PHARMACOLOGICAL REVIEWS
- G protein-coupled receptor kinases: More than just kinases and not only for GPCRs
- (2011) Eugenia V. Gurevich et al. PHARMACOLOGY & THERAPEUTICS
- PGE2 inhibits natural killer and γδ T cell cytotoxicity triggered by NKR and TCR through a cAMP-mediated PKA type I-dependent signaling
- (2010) Ludovic Martinet et al. BIOCHEMICAL PHARMACOLOGY
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- (2010) N. G. Oberprieler et al. BLOOD
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- (2010) A. Y. Wen et al. JOURNAL OF IMMUNOLOGY
- Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials
- (2010) Peter M Rothwell et al. LANCET
- Quantitative Phosphoproteomics Dissection of Seven-transmembrane Receptor Signaling Using Full and Biased Agonists
- (2010) Gitte L. Christensen et al. MOLECULAR & CELLULAR PROTEOMICS
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- (2010) J. I. Kim et al. MOLECULAR CANCER RESEARCH
- The adaptor protein EBP50 is important for localization of the protein kinase A–Ezrin complex in T-cells and the immunomodulating effect of cAMP
- (2009) Anne Jorunn Stokka et al. BIOCHEMICAL JOURNAL
- ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
- (2009) Gabriela Bindea et al. BIOINFORMATICS
- The prostaglandin receptor EP2 activates multiple signaling pathways and -arrestin1 complex formation during mouse skin papilloma development
- (2009) K.-S. Chun et al. CARCINOGENESIS
- The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
- (2009) A. Greenhough et al. CARCINOGENESIS
- Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology
- (2009) Sergiy Kostenko et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor
- (2009) Makoto Miyara et al. IMMUNITY
- Aspirin Use and Survival After Diagnosis of Colorectal Cancer
- (2009) Andrew T. Chan JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling
- (2009) Katia Boniface et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Prostaglandin E2–EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion
- (2009) Chengcan Yao et al. NATURE MEDICINE
- Improved visualization of protein consensus sequences by iceLogo
- (2009) Niklaas Colaert et al. NATURE METHODS
- Prostaglandin E2 enhances T-cell proliferation by inducing the costimulatory molecules OX40L, CD70, and 4-1BBL on dendritic cells
- (2008) P. Krause et al. BLOOD
- G protein βγ subunits: Central mediators of G protein-coupled receptor signaling
- (2008) A. V. Smrcka CELLULAR AND MOLECULAR LIFE SCIENCES
- Phosphorylation of the cAMP-dependent Protein Kinase (PKA) Regulatory Subunit Modulates PKA-AKAP Interaction, Substrate Phosphorylation, and Calcium Signaling in Cardiac Cells
- (2008) Sabrina Manni et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
- (2008) Jürgen Cox et al. NATURE BIOTECHNOLOGY
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