Measurement of polychlorinated biphenyls with hand wipes and matched serum collected from Chinese E-waste dismantling workers: Exposure estimates and implications

To date, dermal/hand-to-mouth exposure to chemicals in the e-waste recycling environment has not been sufficiently understood, and the importance of dermal absorption of chemicals in c-waste dismantling workers remains controversial. In this study, we utilized hand wipes and matched sera to characterize dennal/hand-to-mouth exposure to PCBs for e-waste dismantling workers, and potential effects on thyroid hormones were also assessed. PCB loadings in hand wipes varied from 0.829-265 ng wipe(-1) (11.3-2850 ng m(-2) wipe(-1)), with 37.2 ng wipe(-1) (432 ng m(-2) wipe(-1)) as the median value. Serum concentrations of PCBs ranged from 32.3-3410 ng g(-1) lipid weight (lw) with 364 ng g(-1) lw as the median value. Between wipes and sera, lower-chlorinated congeners (e.g. CB-28, -66, -74, -99,-105 and -118) showed significant associations (p <0.01), but higher-chlorinated congeners (e.g. CB-138, -153, -156, -170, and -180) did not. These lower-chlorinated CBs were the major contributors to estimated dermal/hand-to-mouth average daily doses (ADDS) and the hazard index (HI). Correspondingly, their estimated contributions to serum levels by dermal absorption were also significant, with the contribution of CB-28 being as high as 21.4%. As a consequence, dermal absorption of some low-chlorinated congeners was a non-negligible route for e-waste dismantling workers. Although insignificant association was shown between serum PCBs and thyroid hormones, the potential health risk should be of concern due to the high levels of PCBs observed in workers sera. (C) 2021 Published by Elsevier B.V.

Automated summary

This study investigated dermal/hand-to-mouth exposure to PCBs in e-waste dismantling workers, finding that lower-chlorinated PCB congeners were the major contributors to daily doses and hazard index, while the association between serum PCBs and thyroid hormones was insignificant. However, the potential health risk should be of concern due to high levels of PCBs observed in workers sera.