Article
Environmental Sciences
Adil Dilawar, Baozhang Chen, Zia Ul-Haq, Muhammad Amir, Arfan Arshad, Mujtaba Hassan, Man Guo, Muhammad Shafeeque, Junjun Fang, Boyang Song, Huifang Zhang
Summary: In order to mitigate air pollution, China implemented strict control mechanisms and introduced the Air Pollution Prevention and Control Action Plan (APPCAP) in 2013. This study utilized satellite data, socioeconomic data, and climatological data to investigate the changes in air pollutants and climatic factors in China before and after the implementation of the APPCAP. The results showed that the Action Plan significantly reduced air pollution and had an impact on climatic variations.
Article
Engineering, Environmental
Yuxi Liu, Guannan Geng, Jing Cheng, Yang Liu, Qingyang Xiao, Liangke Liu, Qinren Shi, Dan Tong, Kebin He, Qiang Zhang
Summary: In response to severe air pollution, the Chinese government implemented two phases of clean air actions from 2013 to 2020. The efforts resulted in a decline in PM2.5 but an increase in MDA8 O-3. Both meteorological variations and anthropogenic emissions contributed to the rise of O-3, with anthropogenic emissions playing a more important role. The control of VOC and NO x is crucial for future O-3 pollution mitigation.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Green & Sustainable Science & Technology
Ajit Singh, Tianjiao Guo, Tony Bush, Pedro Abreu, Felix C. P. Leach, Brian Stacey, George Economides, Ruth Anderson, Stuart Cole, G. Neil Thomas, Francis D. D. Pope, Suzanne E. E. Bartington
Summary: This study examined the effects of COVID-19 lockdown measures on traffic flow, active travel, and gaseous pollutant concentrations in Oxford city center. The findings showed significant changes in traffic volume during lockdown periods, resulting in reduced NO and NO2 concentrations but increased O-3 concentrations. The study also observed changes in travel patterns and peak concentration times.
Article
Biochemical Research Methods
Rachel L. Davey, Erick J. Mattson, J. Alex Huffman
Summary: The study demonstrates that gas-phase ozone and nitrogen dioxide can react with proteins in the atmosphere to form nitrotyrosine, potentially impacting human health. Bovine serum albumin samples exposed to urban air in Denver, Colorado were used to investigate protein modification under ambient conditions, highlighting the formation of nitrotyrosine and its relevance to atmospheric exposure studies.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Environmental Sciences
Jason A. Miech, Levi Stanton, Meiling Gao, Paolo Micalizzi, Joshua Uebelherr, Pierre Herckes, Matthew P. Fraser
Summary: Testing the performance of low-cost air quality sensors using various environmental factors showed discrepancies in two sensors, but these were mitigated through sensor-specific calibration, improving overall accuracy. Stable environmental conditions during sensor deployment benefited calibration performance over time.
Article
Engineering, Environmental
Rong Wang, Yechen Yang, Xiaofan Xing, Lin Wang, Jianmin Chen, Xu Tang, Junji Cao, Lidia Morawska, Yves Balkanski, Didier Hauglustaine, Philippe Ciais, Jianmin Ma
Summary: By using a statistical model that takes into account both meteorology and primary emissions, the relationship between PM2.5 concentration and climate change can be better understood. This model reduces errors and suggests that climate change may have a greater impact on PM2.5 than previously thought.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
Hui Zhao, Kaiyu Chen, Zhen Liu, Yuxin Zhang, Tian Shao, Hongliang Zhang
Summary: China formulated the Air Pollution Prevention and Control Action Plan (APPCAP) in 2013 to improve air quality. After its implementation, there was a significant decrease in PM2.5, PM10, SO2, and CO concentrations, while NO2 remained unchanged and O-3 concentration increased. Despite the decrease in PM2.5, over 65% of the population was still exposed to levels higher than the standard, indicating the need for continued efforts in air pollution control.
Article
Environmental Sciences
Ulla Arthur Hvidtfeldt, Jie Chen, Sophia Rodopoulou, Maciej Strak, Kees de Hoogh, Tom Bellander, J. orgen Brandt, Francesco Forastiere, Boel Brynedal, Ole Hertel, Barbara Hoffmann, Klea Katsouyanni, Matthias Ketzel, Karin Leander, Patrik K. E. Magnusson, Gabriele Nagel, Goran Pershagen, Debora Rizzuto, Evangelia Samoli, Rina So, Massimo Stafoggia, Anne Tj Onneland, Gudrun Weinmayr, Kathrin Wolf, Emanuel Zitt, Bert Brunekreef, Gerard Hoek, Ole Raaschou-Nielsen
Summary: This study assessed the association between residential exposure to air pollution and multiple myeloma. The results showed no significant association between long-term ambient air pollution exposure and the incidence of multiple myeloma.
ENVIRONMENTAL RESEARCH
(2023)
Article
Geosciences, Multidisciplinary
Steffen Beirle, Christian Borger, Steffen Doerner, Henk Eskes, Vinod Kumar, Adrianus de Laat, Thomas Wagner
Summary: The global catalog of NOx emissions from point sources, based on TROPOMI measurements of tropospheric NO2 for 2018-2019, identifies and quantifies 451 locations, primarily related to power plants. The catalog reveals that the four largest localized NOx emitters are coal combustion plants in South Africa. Despite incompleteness and underestimation of emissions, the catalog has potential for checking and improving emission inventories.
EARTH SYSTEM SCIENCE DATA
(2021)
Article
Immunology
Yi-Sheng He, Gui-Hong Wang, Qian Wu, Zheng-Dong Wu, Yue Chen, Jin-Hui Tao, Xin-Yu Fang, Zhiwei Xu, Hai-Feng Pan
Summary: The study found a significant association between short-term exposure to NO2 and CO and hospitalizations for acute gout. NO2 was more likely to cause gout in cold seasons.
JOURNAL OF INFLAMMATION RESEARCH
(2021)
Article
Environmental Sciences
Changqing Lin, Yushan Song, Peter K. K. Louie, Zibing Yuan, Ying Li, Minghui Tao, Chengcai Li, Jimmy C. H. Fung, Zhi Ning, Alexis K. H. Lau, Xiang Qian Lao
Summary: The lockdown during the COVID-19 pandemic provides an opportunity to assess the spatial disparity of NO2 reduction on O3 formation in the Greater Bay Area. Despite the increase in O3 levels, NOx emission controls reduce the overall health risk in most regions.
ATMOSPHERIC POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Savita Datta, Anita Sharma, Baerbel Sinha
Summary: DO3SE model is a dry deposition model used to assess tropospheric ozone risk to vegetation. The photosynthetic model is found to be superior to the multiplicative model even for leaf-level studies, and it can accurately assess nighttime pollutant uptake fluxes.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Yiqian Ni, Yang Yang, Hailong Wang, Huimin Li, Mengyun Li, Pinya Wang, Ke Li, Hong Liao
Summary: Ozone pollution is a severe issue in China, posing a serious threat to human health and ecosystems. The differences in ozone changes between eastern China and the rest of China are found to be attributed to meteorological conditions and anthropogenic emissions.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yun Shu, Jingnan Hu, Shaohui Zhang, Wolfgang Schoepp, Wei Tang, Jinhong Du, Janusz Cofala, Gregor Kiesewetter, Robert Sander, Wilfried Winiwarter, Zbigniew Klimont, Jens Borken-Kleefeld, Markus Amann, Haisheng Li, Youjiang He, Jinmin Zhao, Deyuan Xie
Summary: City clusters in China, particularly the 2 + 26 Cities, play a crucial role in reducing air pollutant and greenhouse gas emissions. By adjusting the structure of industries, energy, transport, and land use, significant reductions in PM2.5, SO2, NOx, NH3, and CO2 emissions can be achieved. However, the emission reduction potentials vary greatly among different regions due to differences in energy structure, industrial composition, and policy enforcement.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2022)
Article
Engineering, Environmental
Stephanie R. Schneider, Kristyn Lee, Guadalupe Santos, Jonathan P. D. Abbatt
Summary: As the climate warms, wildfires are increasing in size and frequency, impacting air quality by elevating concentrations of PM2.5, NO2, and CO. This study established an automated method to identify wildfire-influenced periods in urban areas and found that wildfires have a relatively greater impact on pollutants like CO and NO2 due to decreasing urban baseline concentrations over time.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Yacong Bo, Tsung Yu, Ly-Yun Chang, Cui Guo, Changqing Lin, Yiqian Zeng, Bo Huang, Tony Tam, Alexis K. H. Lau, Samuel Y. S. Wong, Xiang Qian Lao
Summary: The study found that higher levels of habitual exercise are associated with a lower risk of death from cancer, while higher levels of PM2.5 exposure are associated with a higher risk of death from cancer. Participants with high levels of exercise and low levels of PM2.5 exposure had a 35% lower risk of death from cancer compared to those with low levels of exercise and high levels of PM2.5 exposure.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Tzu-Jung Wong, Tsung Yu, Ly-Yun Chang, Xiang Qian Lao
Summary: The trajectory of height, weight, and BMI in the Taiwanese population varies by age, sex, birth cohort, and education. Younger generations, especially men, and individuals with lower education levels, particularly women, have higher levels of BMI. Educational disparities have a larger impact on women's BMI.
Article
Environmental Sciences
Cui Guo, Ly-Yun Chang, Yacong Bo, Changqing Lin, Alexis K. H. Lau, Tony Tam, Xiang Qian Lao
Summary: This study investigated the association between life-course exposure to PM2.5 and incident hypertension in adulthood. The results showed that for every 10µg/m3 increase in PM2.5, the overall risk of adulthood hypertension increased by 40%. The health effects of PM2.5 exposure at different life stages on incident hypertension were generally independent of each other. The study suggests that life-course control of air pollution exposure should be implemented to alleviate the burden of adulthood hypertension.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Construction & Building Technology
Helen H. L. Kwok, Jack C. P. Cheng, Alison T. Y. Li, Jimmy C. K. Tong, Alexis K. H. Lau
Summary: The objective of this study is to develop a methodology to investigate the impact of velocity variations along fresh air shafts on thermal comfort and indoor air quality of multiple floors. The study conducted steady-state CFD simulations on fresh air shafts and office floors, using Building Information Modeling technology to accurately represent the geometry. The results showed that dividing the shafts into two parts improved the fresh air distribution and indoor air quality.
JOURNAL OF BUILDING ENGINEERING
(2022)
Article
Public, Environmental & Occupational Health
Yacong C. Bo, Tsung Yu, Cui Guo, Changqing C. Lin, Hsiao Ting Yang, Ly-yun Y. Chang, G. N. Thomas, Tony Tam, Alexis K. H. Lau, Xiang Qian Lao
Summary: This study examined the combined effects of habitual exercise and chronic exposure to ambient fine particulate matter 2.5 on cardiovascular mortality in adults in Taiwan. The results showed that habitual exercise has beneficial effects on cardiovascular mortality, and these effects were not reduced by exposure to particulate matter 2.5.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2023)
Correction
Cardiac & Cardiovascular Systems
Hai Deng, Peng Hu, Huoxing Li, Huanning Zhou, Xiuyi Wu, Maohua Yuan, Xueru Duan, Miaochan Lao, Chuchu Wu, Murui Zheng, Xiang Qian Lao, Wenjing Zhao, Xudong Liu
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Peripheral Vascular Disease
Yacong Bo, Tsung Yu, Cui Guo, Ly-yun Chang, Junjie Huang, Martin C. S. Wong, Tony Tam, Xiang Qian Lao
Summary: This study found that young adults with stage 1 or stage 2 isolated systolic hypertension (ISH), isolated diastolic hypertension (IDH), and systolic and diastolic hypertension (SDH) have an increased risk of cardiovascular death compared to those with normal blood pressure. Regardless of blood pressure stage, SDH was associated with a higher cardiovascular mortality risk than IDH and ISH.
JOURNAL OF HYPERTENSION
(2023)
Article
Construction & Building Technology
Lu Li, Yingdong He, Hui Zhang, Jimmy C. H. Fung, Alexis K. H. Lau
Summary: This paper describes the development and application of a multi-objective AI algorithm for practical environmental control, aiming to optimize indoor air quality, thermal comfort levels, and energy efficiency in buildings.
BUILDING AND ENVIRONMENT
(2023)
Article
Environmental Sciences
Jinjian Chen, Yiqian Zeng, Alexis K. H. Lau, Cui Guo, Xianglin Wei, Changqing Lin, Bo Huang, Xiang Qian Lao
Summary: A prospective cohort study in Hong Kong reveals that air pollution has detrimental effects on respiratory health, particularly in older male schoolchildren.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Environmental Sciences
Wenwei Che, Yumiao Zhang, Changqing Lin, Yik Him Fung, Jimmy C. H. Fung, Alexis K. H. Lau
Summary: Traditional air quality data with low spatial resolution cannot accurately capture the detailed air pollution exposure in complex urban areas. This study developed an ultra-fine resolution modeling system using big data fusion technology to provide street-level air quality data. The findings revealed sharp fine-scale variabilities in air pollution within individual city blocks. The study also highlighted the environmental inequities in population exposure to air pollutants caused by unfavorable city planning.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Environmental Sciences
Changqing Lin, Jimmy C. H. Fung, Chao Ren, Edward Y. Y. Ng, Yuguo Li, Yueyang He, Kenneth K. M. Leung, Zhi Ning, Alexis K. H. Lau
Summary: This study uses a Light Detection and Ranging (LiDAR) system to measure wind profiles in an urban site in Hong Kong, and investigates the characteristics of ozone transport in the planetary boundary layer (PBL). The study finds that during ozone pollution episodes, there is increased regional transport from the Greater Bay Area (GBA), resulting in a predominant westerly component in the ozone flux. Additionally, clockwise veering winds are observed from the ground to the top of the PBL.
ATMOSPHERIC ENVIRONMENT
(2023)
Article
Environmental Sciences
Jianxiu Liu, Ruidong Liu, Yao Zhang, Xiangqian Lao, Kate L. Mandeville, Xindong Ma, Qian Di
Summary: Engaging in leisure-time physical activity improves cognitive function, even under exposure to PM2.5 pollution, although the cognitive benefits are attenuated by PM2.5 exposure.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Clinical Neurology
Yacong Bo, Yongjian Zhu, Xiaoan Zhang, Hui Chang, Junxi Zhang, Xiang Qian Lao, Zengli Yu
Summary: This study evaluated the association between ambient PM2.5 and stroke burden at global, regional, and national levels. The findings showed an increasing trend in stroke burden attributable to ambient PM2.5 over the past 30 years.
Article
Geochemistry & Geophysics
Rui Wang, Lin Su, Wai Kin Wong, Alexis K. H. Lau, Jimmy C. H. Fung
Summary: Accurate and timely rainfall nowcasting is crucial for public safety. While deep-learning models have outperformed traditional methods in heavy rainfall nowcasting, they still face limitations in forecast skills and increasing blurriness over time. This study introduces a new heavy rainfall nowcasting model, TS-RainGAN, that utilizes a task-segmented architecture with two modules: MaskPredNet predicts spatial coverage of rainfall categories, while IntensityGAN predicts rainfall intensity based on that coverage. TS-RainGAN accurately captures spatiotemporal features and provides skillful precipitation predictions with reduced blurriness, enabling competitive forecast skills for district-level nowcasting.
IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING
(2023)
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)