A systematic literature review of burden of illness in adults with uncontrolled moderate/severe asthma

Characterisation of patients with severe asthma in the UK Severe Asthma Registry in the biologic era

(2020) David J Jackson et al.   THORAX

The Burden of Severe Asthma in France: A Case-Control Study Using a Medical Claims Database

(2019) Arnaud Bourdin et al.   Journal of Allergy and Clinical Immunology-In Practice

Relevance of Th2 markers in the assessment and therapeutic management of severe allergic asthma: a real life perspective

(2019) M Caminati et al.   JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY

The prevalence and disease burden of severe eosinophilic asthma in Japan

(2019) Tadao Nagasaki et al.   JOURNAL OF ASTHMA

Severe asthma and bronchiectasis

(2019) Marta García-Clemente et al.   JOURNAL OF ASTHMA

Demographic Characteristics, Comorbidities, and Exacerbation Frequency Among Patients Enrolled in the Chronicle Study: A Real-World, Prospective, Observational Study of US, Subspecialist-Treated Adults with Severe Asthma

(2019) Weily Soong et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sputum proteomic signature of gastro-oesophageal reflux in patients with severe asthma

(2019) K. Tariq et al.   RESPIRATORY MEDICINE

Symptoms and perception of airway obstruction in asthma: clinical implications for use of reliever medications

(2019) Peter J. Barnes et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Characterizing patients with asthma who received Global Initiative for Asthma steps 4‐5 therapy and managed in a specialty care setting

(2018) Brian Stone et al.   ALLERGY AND ASTHMA PROCEEDINGS

Bronchiectasis in severe asthma

(2018) Isabel Coman et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Real-world health care utilization and effectiveness of omalizumab for the treatment of severe asthma

(2018) Mina Tadrous et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Working while unwell: Workplace impairment in people with severe asthma

(2018) S. A. Hiles et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Factors reducing omalizumab response in severe asthma

(2018) B. Sposato et al.   European Journal of Internal Medicine

Omalizumab effectiveness in patients with severe allergic asthma according to blood eosinophil count: the STELLAIR study

(2018) Marc Humbert et al.   EUROPEAN RESPIRATORY JOURNAL

A randomised clinical trial of feedback on inhaler adherence and technique in patients with severe uncontrolled asthma

(2018) Imran Sulaiman et al.   EUROPEAN RESPIRATORY JOURNAL

Burden of asthma among patients adherent to ICS/LABA: A real-world study

(2018) Jill Davis et al.   JOURNAL OF ASTHMA

Economic impact of severe asthma in Spain: multicentre observational longitudinal study

(2018) Carlos Melero et al.   JOURNAL OF ASTHMA

Total Health-Related Costs Due to Absenteeism, Presenteeism, and Medical and Pharmaceutical Expenses in Japanese Employers

(2018) Tomohisa Nagata et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

After asthma: redefining airways diseases

(2018) Ian D Pavord et al.   LANCET

Real-world safety and efficacy of omalizumab in patients with severe allergic asthma: A long-term post-marketing study in Japan

(2018) Mitsuru Adachi et al.   RESPIRATORY MEDICINE

Improving the global diagnosis and management of asthma in children

(2018) Warren Lenney et al.   THORAX

Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age

(2018) W. Gerald Teague et al.   Journal of Allergy and Clinical Immunology-In Practice

Asthma control and quality of life in a real-life setting: a cross-sectional study of adult asthma patients in Japan (ACQUIRE-2)

(2018) Mitsuru Adachi et al.   JOURNAL OF ASTHMA

Treatable traits can be identified in a severe asthma registry and predict future exacerbations

(2018) Vanessa M. McDonald et al.   RESPIROLOGY

Remotely Monitored Therapy and Nitric Oxide Suppression Identifies Non-Adherence in Severe Asthma

(2018) Liam G Heaney et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

PRS70 - REAL-LIFE RETROSPECTIVE OBSERVATIONAL STUDY TO DETERMINE THE PREVALENCE AND ECONOMIC BURDEN OF SEVERE ASTHMA

(2018) A. Sicras-Mainar et al.   VALUE IN HEALTH

The Severe Asthma Network in Italy: Findings and Perspectives

(2018) Enrico Heffler et al.   Journal of Allergy and Clinical Immunology-In Practice

The North-Western Italian experience with anti IL-5 therapy amd comparison with regulatory trials

(2018) Diego Bagnasco et al.   World Allergy Organization Journal

Follow-up of patients with uncontrolled asthma: clinical features of asthma patients according to the level of control achieved (the COAS study)

(2017) Rosa Munoz-Cano et al.   EUROPEAN RESPIRATORY JOURNAL

Clinical and biological characteristics of the French COBRA cohort of adult subjects with asthma

(2017) Marina Pretolani et al.   EUROPEAN RESPIRATORY JOURNAL

Lack of asthma and rhinitis control in general practitioner-managed patients prescribed fixed-dose combination therapy in Australia

(2017) Sinthia Bosnic-Anticevich et al.   JOURNAL OF ASTHMA

Asthma control and disease burden in patients with asthma and allergic comorbidities

(2017) Lulu K. Lee et al.   JOURNAL OF ASTHMA

Healthcare resource use and costs of severe, uncontrolled eosinophilic asthma in the UK general population

(2017) Marjan Kerkhof et al.   THORAX

The Estimation and Inclusion of Presenteeism Costs in Applied Economic Evaluation: A Systematic Review

(2017) Jesse Kigozi et al.   VALUE IN HEALTH

The frequency of asthma exacerbations and healthcare utilization in patients with asthma from the UK and USA

(2017) Robert Y. Suruki et al.   BMC Pulmonary Medicine

Predicting future risk of exacerbations in Japanese patients with adult asthma: A prospective 1-year follow up study

(2017) Akihiko Tanaka et al.   ALLERGOLOGY INTERNATIONAL

The impact of poor asthma control among asthma patients treated with inhaled corticosteroids plus long-acting β2-agonists in the United Kingdom: a cross-sectional analysis

(2017) Ian D. Pavord et al.   npj Primary Care Respiratory Medicine

Controle da asma e qualidade de vida em pacientes com asma moderada ou grave

(2017) Eanes Delgado Barros Pereira et al.   Jornal Brasileiro de Pneumologia

The real world effect of omalizumab add on therapy for patients with moderate to severe allergic asthma: The ASTERIX Observational study

(2017) Mohit Bhutani et al.   PLoS One

Comparación de costes y resultados clínicos entre la administración hospitalaria o ambulatoria de omalizumab, en pacientes con asma grave no controlada

(2016) Eusebi Chiner et al.   ARCHIVOS DE BRONCONEUMOLOGIA

The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases

(2016) Mome Mukherjee et al.   BMC Medicine

Association Between Insomnia and Asthma Burden in the Severe Asthma Research Program (SARP) III

(2016) Faith S. Luyster et al.   CHEST

Real-life effectiveness of omalizumab in severe allergic asthma above the recommended dosing range criteria

(2016) M. Hew et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Cost-Effectiveness Analysis of Omalizumab for the Treatment of Severe Persistent Asthma in Real Clinical Practice in Spain

(2016) María del Carmen Vennera et al.   CLINICAL DRUG INVESTIGATION

Burden of systemic glucocorticoid-related complications in severe asthma

(2016) Patrick Lefebvre et al.   CURRENT MEDICAL RESEARCH AND OPINION

Effectiveness and response predictors of omalizumab in a severe allergic asthma population with a high prevalence of comorbidities: the Australian Xolair Registry

(2016) P. G. Gibson et al.   INTERNAL MEDICINE JOURNAL

Improved quality of life in asthma patients under long-term therapy: Assessed by AHQ-Japan

(2016) Yuji Tohda et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Measuring the cost of poor asthma control and exacerbations

(2016) Patrick W. Sullivan et al.   JOURNAL OF ASTHMA

Antileukotriene Agents Versus Long-Acting Beta-Agonists in Older Adults with Persistent Asthma: A Comparison of Add-On Therapies

(2016) Shoroq M. Altawalbeh et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Effects of omalizumab in severe asthmatics across ages: A real life Italian experience

(2016) B. Sposato et al.   RESPIRATORY MEDICINE

Bronchodilator response as a marker of poor asthma control

(2016) Enrico Heffler et al.   RESPIRATORY MEDICINE

Comorbidity in severe asthma requiring systemic corticosteroid therapy: cross-sectional data from the Optimum Patient Care Research Database and the British Thoracic Difficult Asthma Registry

(2016) Joan Sweeney et al.   THORAX

Impact of omalizumab on treatment of severe allergic asthma in UK clinical practice: a UK multicentre observational study (the APEX II study)

(2016) Robert M Niven et al.   BMJ Open

Comparación de costes y resultados clínicos entre la administración hospitalaria o ambulatoria de omalizumab, en pacientes con asma grave no controlada

(2016) Eusebi Chiner et al.   ARCHIVOS DE BRONCONEUMOLOGIA

Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts

(2016) Michael C Peters et al.   Lancet Respiratory Medicine

Utilization and Costs of Severe Uncontrolled Asthma in a Managed-Care Setting

(2016) Robert S. Zeiger et al.   Journal of Allergy and Clinical Immunology-In Practice

Economic Burden of Illness Among Patients with Severe Asthma in a Managed Care Setting

(2016) Benjamin Chastek et al.   Journal of Managed Care & Specialty Pharmacy

Dedicated Severe Asthma Services Improve Health-care Use and Quality of Life

(2015) David Gibeon et al.   CHEST

Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

(2015) Dominick E. Shaw et al.   EUROPEAN RESPIRATORY JOURNAL

Characterizing the severe asthma population in the United States: claims-based analysis of three treatment cohorts in the year prior to treatment escalation

(2015) Patrick W. Sullivan et al.   JOURNAL OF ASTHMA

Fluticasone furoate (FF)/vilanterol (100/25 mcg or 200/25 mcg) or FF (100 mcg) in persistent asthma

(2015) David I. Bernstein et al.   JOURNAL OF ASTHMA

Misdiagnosis Among Frequent Exacerbators of Clinically Diagnosed Asthma and COPD in Absence of Confirmation of Airflow Obstruction

(2015) Vipul V. Jain et al.   LUNG

One-year outcomes of inhaled controller therapies added to systemic corticosteroids after asthma-related hospital discharge

(2015) Mohsen Sadatsafavi et al.   RESPIRATORY MEDICINE

Obstructive Sleep Apnea Risk, Asthma Burden, and Lower Airway Inflammation in Adults in the Severe Asthma Research Program (SARP) II

(2015) Mihaela Teodorescu et al.   Journal of Allergy and Clinical Immunology-In Practice

Effect of Switching from Salmeterol/Fluticasone to Formoterol/Budesonide Combinations in Patients with Uncontrolled Asthma

(2015) Taisuke Akamatsu et al.   ALLERGOLOGY INTERNATIONAL

The relationship between asthma, asthma control and economic outcomes in the United States

(2014) Patrick W. Sullivan et al.   JOURNAL OF ASTHMA

Omalizumab management beyond clinical trials: The added value of a network model

(2014) Marco Caminati et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

The cost of treating severe refractory asthma in the UK: an economic analysis from the British Thoracic Society Difficult Asthma Registry

(2014) S. O'Neill et al.   THORAX

Asthma Exacerbation Rates in Adults Are Unchanged Over a 5-Year Period Despite High-Intensity Therapy

(2014) Michael Schatz et al.   Journal of Allergy and Clinical Immunology-In Practice

High Blood Eosinophil Count Is a Risk Factor for Future Asthma Exacerbations in Adult Persistent Asthma

(2014) Robert S. Zeiger et al.   Journal of Allergy and Clinical Immunology-In Practice

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

(2013) K. F. Chung et al.   EUROPEAN RESPIRATORY JOURNAL

Effectiveness of Omalizumab in Severe Allergic Asthma: A Retrospective UK Real-World Study

(2013) Neil Barnes et al.   JOURNAL OF ASTHMA

Effects of Omalizumab in Non-Atopic Asthma: Results from a Spanish Multicenter Registry

(2013) Luis Pérez de Llano et al.   JOURNAL OF ASTHMA

Assessment of asthma control: The SERENA study

(2013) Antonio Corrado et al.   RESPIRATORY MEDICINE

Detection of exacerbations in asthma based on electronic diary data: results from the 1-year prospective BIOAIR study

(2013) Maciej Kupczyk et al.   THORAX

Statin use and asthma control in patients with severe asthma

(2013) Amir A Zeki et al.   BMJ Open

Impact of omalizumab on emergency-department visits, hospitalizations, and corticosteroid use among patients with uncontrolled asthma

(2012) Marie-Hélène Lafeuille et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Omalizumab versus ‘Usual Care’: Results from a Naturalistic Longitudinal Study in Routine Care

(2012) H.-U. Wittchen et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

The relationship between combination inhaled corticosteroid and long-acting β-agonist use and severe asthma exacerbations in a diverse population

(2012) Karen E. Wells et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Omalizumab Therapy in Severe Asthma: Experience from the Spanish Registry—Some New Approaches

(2012) María Del Carmen Vennera et al.   JOURNAL OF ASTHMA

US general population norms for telephone administration of the SF-36v2

(2012) Gregory A. Maglinte et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Natural history and risk factors of obstructive changes over a 10-year period in severe asthma

(2012) Kazuto Matsunaga et al.   RESPIRATORY MEDICINE

1-year prospective real life monitoring of asthma control and quality of life in Italy

(2012) Claudio Terzano et al.   RESPIRATORY RESEARCH

Factors associated with health-related quality of life in adults with asthma. A cross-sectional study

(2012) Francisco-Javier Gonzalez-Barcala et al.   MULTIDISCIPLINARY RESPIRATORY MEDICINE

Association Between Consistent Omalizumab Treatment and Asthma Control

(2012) Marie-Hélène Lafeuille et al.   Journal of Allergy and Clinical Immunology-In Practice

Obesity and aspirin intolerance are risk factors for difficult-to-treat asthma in Japanese non-atopic women

(2011) Y. Fukutomi et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Uncontrolled persistent allergic asthma in practice: eXpeRience registry baseline characteristics

(2011) Gert-Jan Braunstahl et al.   CURRENT MEDICAL RESEARCH AND OPINION

Concomitant Asthma Medication Use in Patients Receiving Omalizumab: Results from Three Large Insurance Claims Databases

(2011) Marie-Hélène Lafeuille et al.   JOURNAL OF ASTHMA

Real-life prospective study on asthma control in Italy: Cross-sectional phase results

(2011) Luigi Allegra et al.   RESPIRATORY MEDICINE

Evaluation of the asthma control test: A reliable determinant of disease stability and a predictor of future exacerbations

(2011) FANNY W.S. KO et al.   RESPIROLOGY

Sleep quality and asthma control and quality of life in non-severe and severe asthma

(2011) Faith S. Luyster et al.   Sleep and Breathing

Associations between fluctuations in lung function and asthma control in two populations with differing asthma severity

(2011) C. Thamrin et al.   THORAX

Addition of Leukotriene Receptor Antagonists to Inhaled Corticosteroids Improved QOL of Patients with Bronchial Asthma Surveyed in Suburban Tokyo, Japan

(2011) Nobuharu Ohshima et al.   ALLERGOLOGY INTERNATIONAL

Impact of asthma control on sleep, attendance at work, normal activities, and disease burden

(2010) Debra A. Wertz et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Asthma control and activity limitations: insights from the Real-world Evaluation of Asthma Control and Treatment (REACT) Study

(2010) Tmirah Haselkorn et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Factores asociados con el control del asma en pacientes de atención primaria en España: el estudio CHAS

(2010) Francisco Javier González Barcala et al.   ARCHIVOS DE BRONCONEUMOLOGIA

Measuring asthma control: a comparison of three classification systems

(2010) P. M. O'Byrne et al.   EUROPEAN RESPIRATORY JOURNAL

Long-acting  2-agonists in adult asthma and the pattern of risk of death and severe asthma outcomes: a study using the GPRD

(2010) F. de Vries et al.   EUROPEAN RESPIRATORY JOURNAL

Anaphylaxis epidemiology in patients with and patients without asthma: A United Kingdom database review

(2010) Antonio González-Pérez et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Factors Associated With the Control of Severe Asthma

(2010) Juan Luis Rodriguez Hermosa et al.   JOURNAL OF ASTHMA

Omalizumab reduces oral corticosteroid use in patients with severe allergic asthma: Real-life data

(2010) M. Molimard et al.   RESPIRATORY MEDICINE

Italian real-life experience of omalizumab

(2010) M. Cazzola et al.   RESPIRATORY MEDICINE

Refractory asthma in the UK: cross-sectional findings from a UK multicentre registry

(2010) L. G. Heaney et al.   THORAX

The Prevalence of Nonadherence in Difficult Asthma

(2009) Jacqueline Gamble et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

An Official American Thoracic Society/European Respiratory Society Statement: Asthma Control and Exacerbations

(2009) Helen K. Reddel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Phenotypic determinants of uncontrolled asthma

(2009) Valérie Siroux et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Multivariate Analysis of Risk Factors for the Air-Trapping Asthmatic Phenotype as Measured by Quantitative CT Analysis

(2008) Ashley Busacker et al.   CHEST

High-dose inhaled corticosteroids versus add-on long-acting β-agonists in asthma: An observational study

(2008) Mike Thomas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY