Deletion of fabN in Enterococcus faecalis results in unsaturated fatty acid auxotrophy and decreased release of inflammatory cytokines

Skin-Specific Unsaturated Fatty Acids Boost the Staphylococcus aureus Innate Immune Response

(2015) Minh Thu Nguyen et al.   INFECTION AND IMMUNITY

Enterococcus faecalis Glycolipids Modulate Lipoprotein-Content of the Bacterial Cell Membrane and Host Immune Response

(2015) Christian Theilacker et al.   PLoS One

Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides

(2015) Guillermo Martinez de Tejada et al.   Scientific Reports

FabH Mutations Confer Resistance to FabF-Directed Antibiotics in Staphylococcus aureus

(2014) Joshua B. Parsons et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Incorporation of Exogenous Fatty Acids Protects Enterococcus faecalis from Membrane-Damaging Agents

(2014) Holly E. Saito et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Role of Glycolipids in the Pathogenesis of Enterococcus faecalis Urinary Tract Infection

(2014) Ann-Kristin Diederich et al.   PLoS One

Bacterial lipids: Metabolism and membrane homeostasis

(2013) Joshua B. Parsons et al.   PROGRESS IN LIPID RESEARCH

The Two Functional Enoyl-Acyl Carrier Protein Reductases of Enterococcus faecalis Do Not Mediate Triclosan Resistance

(2013) L. Zhu et al.   mBio

The use of platensimycin and platencin to fight antibiotic resistance

(2013) Adil Allahverdiyev et al.   Infection and Drug Resistance

Role of mprF1 and mprF2 in the Pathogenicity of Enterococcus faecalis

(2012) Yinyin Bao et al.   PLoS One

Deletion of the glycosyltransferase bgsB of Enterococcus faecalis leads to a complete loss of glycolipids from the cell membrane and to impaired biofilm formation

(2011) Christian Theilacker et al.   BMC MICROBIOLOGY

Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria

(2011) Yuki Kinjo et al.   NATURE IMMUNOLOGY

Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors

(2011) J. B. Parsons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functions of the Clostridium acetobutylicium FabF and FabZ proteins in unsaturated fatty acid biosynthesis

(2009) Lei Zhu et al.   BMC MICROBIOLOGY

Glycolipids are involved in biofilm accumulation and prolonged bacteraemia inEnterococcus faecalis

(2009) Christian Theilacker et al.   MOLECULAR MICROBIOLOGY

Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens

(2009) Sophie Brinster et al.   NATURE

TLR2 – promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity

(2008) Ulrich Zähringer et al.   IMMUNOBIOLOGY

The biology and future prospects of antivirulence therapies

(2007) Lynette Cegelski et al.   NATURE REVIEWS MICROBIOLOGY