Melatonin Ameliorates Valproic Acid-Induced Neurogenesis Impairment: The Role of Oxidative Stress in Adult Rats

Protective effects of melatonin against valproic acid-induced memory impairments and reductions in adult rat hippocampal neurogenesis

(2019) Anusara Aranarochana et al.   NEUROSCIENCE

Effect of Melatonin on Attenuating the Isoflurane-Induced Oxidative Damage is Related to PKCα/Nrf2 Signaling Pathway in Developing Rats

(2018) Bei Li et al.   BRAIN RESEARCH BULLETIN

Neuroprotective Properties of Asiatic Acid against 5-Fluorouracil Chemotherapy in the Hippocampus in an Adult Rat Model

(2018) Jariya Welbat et al.   Nutrients

Transcription factor NRF2 controls the fate of neural stem cells in the subgranular zone of the hippocampus

(2017) Natalia Robledinos-Antón et al.   Redox Biology

Kaempferia parviflora extract ameliorates the cognitive impairments and the reduction in cell proliferation induced by valproic acid treatment in rats

(2016) Jariya Umka Welbat et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Effects and mechanisms of melatonin on neural differentiation of induced pluripotent stem cells

(2016) Tao Shu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Melatonin Stimulates the SIRT1/Nrf2 Signaling Pathway Counteracting Lipopolysaccharide (LPS)-Induced Oxidative Stress to Rescue Postnatal Rat Brain

(2016) Shahid Ali Shah et al.   CNS Neuroscience & Therapeutics

Fluoxetine prevents the memory deficits and reduction in hippocampal cell proliferation caused by valproic acid

(2016) Jariya Umka Welbat et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Effect of Melatonin and Resveratrol against Memory Impairment and Hippocampal Damage in a Rat Model of Vascular Dementia

(2016) Dongfang Shen et al.   NEUROIMMUNOMODULATION

Protective effect of melatonin on soluble Aβ1–42-induced memory impairment, astrogliosis, and synaptic dysfunction via the Musashi1/Notch1/Hes1 signaling pathway in the rat hippocampus

(2016) Shuman Zhang et al.   Alzheimers Research & Therapy

Valproic acid suppresses the self-renewal and proliferation of head and neck cancer stem cells

(2015) SANG HYUK LEE et al.   ONCOLOGY REPORTS

Valproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells

(2014) Periyasamy Palsamy et al.   EXPERIMENTAL EYE RESEARCH

Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2–ARE signaling pathway as a potential mechanism

(2014) Ke Ding et al.   FREE RADICAL BIOLOGY AND MEDICINE

Melatonin pretreatment prevented the effect of dexamethasone negative alterations on behavior and hippocampal neurogenesis in the mouse brain

(2014) Nootchanart Ruksee et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Oxidative Stress and Neurodegenerative Disorders

(2013) Jie Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chronic intracerebroventricular infusion of nerve growth factor improves recognition memory in the rat

(2013) Amy M. Birch et al.   NEUROPHARMACOLOGY

Melatonin treatment increases the transcription of cell proliferation-related genes prior to inducing cell death in C6 glioma cells in vitro

(2013) JIAGUI QU et al.   Oncology Letters

Melatonin activates the Nrf2-ARE pathway when it protects against early brain injury in a subarachnoid hemorrhage model

(2012) Zhong Wang et al.   JOURNAL OF PINEAL RESEARCH

An in vitro approach to assess the neurotoxicity of valproic acid-induced oxidative stress in cerebellum and cerebral cortex of young rats

(2012) S. Chaudhary et al.   NEUROSCIENCE

Hippocampal-prefrontal dynamics in spatial working memory: Interactions and independent parallel processing

(2011) John C. Churchwell et al.   BEHAVIOURAL BRAIN RESEARCH

Valproic Acid Increases Formation of Reactive Oxygen Species and Induces Apoptosis in Postimplantation Embryos: A Role for Oxidative Stress in Valproic Acid-Induced Neural Tube Defects

(2011) E. W. Y. Tung et al.   MOLECULAR PHARMACOLOGY

Quiescent and Active Hippocampal Neural Stem Cells with Distinct Morphologies Respond Selectively to Physiological and Pathological Stimuli and Aging

(2010) Sebastian Lugert et al.   Cell Stem Cell

RBPJ -Dependent Signaling Is Essential for Long-Term Maintenance of Neural Stem Cells in the Adult Hippocampus

(2010) O. Ehm et al.   JOURNAL OF NEUROSCIENCE

Nestin Is Required for the Proper Self-Renewal of Neural Stem Cells

(2010) Donghyun Park et al.   STEM CELLS

Adult-Born Hippocampal Dentate Granule Cells Undergoing Maturation Modulate Learning and Memory in the Brain

(2009) W. Deng et al.   JOURNAL OF NEUROSCIENCE

Peroxiredoxin II preserves cognitive function against age-linked hippocampal oxidative damage

(2009) Sun-Uk Kim et al.   NEUROBIOLOGY OF AGING

Melatonin Modulates Cell Survival of New Neurons in the Hippocampus of Adult Mice

(2009) Gerardo Ramírez-Rodríguez et al.   NEUROPSYCHOPHARMACOLOGY

Valproic acid reduces spatial working memory and cell proliferation in the hippocampus

(2009) J. Umka et al.   NEUROSCIENCE

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease

(2009) K. Kanninen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Melatonin maintains adult hippocampal neurogenesis and cognitive functions after irradiation

(2009) Kailash Manda et al.   PROGRESS IN NEUROBIOLOGY

Importance of the lipid peroxidation biomarkers and methodological aspects FOR malondialdehyde quantification

(2009) Denise Grotto et al.   QUIMICA NOVA

The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease

(2008) Marcus J. Calkins et al.   ANTIOXIDANTS & REDOX SIGNALING

Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway

(2008) Gyung-Ah Jung et al.   BMC CELL BIOLOGY

Melatonin, hormone of darkness and more – occurrence, control mechanisms, actions and bioactive metabolites

(2008) R. Hardeland   CELLULAR AND MOLECULAR LIFE SCIENCES

p21Cip1 restricts neuronal proliferation in the subgranular zone of the dentate gyrus of the hippocampus

(2008) R. N. Pechnick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylase inhibitors trichostatin A and valproic acid induce cell cycle arrest and p21 expression in immortalized human endometrial stromal cells

(2007) Yan Wu et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology