Aziridine Opening via a Phenonium Ion Enables Synthesis of Complex Phenethylamine Derivatives

Formal Enone α-Arylation via I(III)-Mediated Aryl Migration/Elimination

(2021) Bruna S. Martins et al.   ORGANIC LETTERS

Synthesis of β-Phenethylamines via Ni/Photoredox Cross-Electrophile Coupling of Aliphatic Aziridines and Aryl Iodides

(2020) Talia J. Steiman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reagent Control Enables Selective and Regiodivergent Opening of Unsymmetrical Phenonium Ions

(2020) Shiyan Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Silico Screening for Novel Leucine Aminopeptidase Inhibitors with 3,4-Dihydroisoquinoline Scaffold

(2020) Joanna Ziemska et al.   MOLECULES

Enantioselective Aryl-Iodide-Catalyzed Wagner–Meerwein Rearrangements

(2020) Hayden A. Sharma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aryl Migration on Graphene

(2020) Maggie He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Revisiting the ‘Phenonium Phenomenon’: Regiodivergent Opening of Nonsymmetrical Phenonium Ions with Halide Nucleophiles

(2020) Nicholas J. Race et al.   SYNLETT

Catalytic Strategy for Regioselective Arylethylamine Synthesis

(2019) Allyson J. Boyington et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

a-Arylation of Carbonyl Compounds by Oxidative C−C Bond Activation

(2019) Jing Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Substituted tetrahydroisoquinolines: synthesis, characterization, antitumor activity and other biological properties

(2018) A. Sergi Capilla et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric Copper-Catalyzed Intermolecular Aminoarylation of Styrenes: Efficient Access to Optical 2,2-Diarylethylamines

(2017) Dinghai Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovery of an 8-methoxytetrahydroisoquinoline derivative as an orally active N-type calcium channel blocker for neuropathic pain without CYP inhibition liability

(2015) Takashi Ogiyama et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Lewis Acid Catalyzed SN2-Type Ring Opening of N-Activated Aziridines with Electron-Rich Arenes/Heteroarenes

(2013) Manas K. Ghorai et al.   JOURNAL OF ORGANIC CHEMISTRY

Fused Piperidines as a Novel Class of Potent and Orally Available Transient Receptor Potential Melastatin Type 8 (TRPM8) Antagonists

(2012) Nuria A. Tamayo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Escape from Flatland 2: complexity and promiscuity

(2012) Frank Lovering   MedChemComm

Catalytic Enantioselective Aziridoarylation of Aryl Cinnamyl Ethers toward Synthesis oftrans-3-Amino-4-arylchromans

(2011) Saumen Hajra et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Stereoselective7-Endo-Trig/Ring Contraction Cascade To Construct Pyrrolo[1,2-a]quinoline Derivatives

(2010) Xinyu Li et al.   ORGANIC LETTERS

Synthesis, analgesic and anti-inflammatory activity of (1Z,3Z)-4-aryl-4-hydroxy-1-(3,3-dialkyl-3,4-dihydroisoquinoline-1(2H)-ylidene)-but-3-en-4-ones

(2010) V. V. Khalturina et al.   PHARMACEUTICAL CHEMISTRY JOURNAL

A Catalytic and Enantioselective Synthesis oftrans-2-Amino-1- aryltetralins

(2009) Saumen Hajra et al.   ADVANCED SYNTHESIS & CATALYSIS

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dopamine receptors in the learning, memory and drug reward circuitry

(2009) Jeffrey W. Dalley et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Synthesis of Hexahydro-1H-benzo[c]chromen-1-amines via the Intramolecular Ring-Opening Reactions of Aziridines by π-Nucleophiles

(2008) Stephen Bergmeier et al.   SYNTHESIS-STUTTGART

FeCl3: an efficient catalyst for reactions of electron-rich arenes with imines or aziridines

(2008) Zhiyong Wang et al.   TETRAHEDRON