Ribonucleotides embedded in template DNA impair mitochondrial RNA polymerase progression

Cryo-EM Structures Reveal Transcription Initiation Steps by Yeast Mitochondrial RNA Polymerase

(2020) Brent De Wijngaert et al.   MOLECULAR CELL

RNase H1 directs origin-specific initiation of DNA replication in human mitochondria

(2019) Viktor Posse et al.   PLoS Genetics

TEFM regulates both transcription elongation and RNA processing in mitochondria

(2019) Shan Jiang et al.   EMBO REPORTS

Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes

(2019) Hauke S. Hillen et al.   CELL

The presence of rNTPs decreases the speed of mitochondrial DNA replication

(2018) Josefin M. E. Forslund et al.   PLoS Genetics

Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired

(2017) Paulina H. Wanrooij et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA

(2017) Anna-Karin Berglund et al.   PLoS Genetics

Maintenance and Expression of Mammalian Mitochondrial DNA

(2016) Claes M. Gustafsson et al.   Annual Review of Biochemistry

Human Mitochondrial Transcription Factor B2 Is Required for Promoter Melting during Initiation of Transcription

(2016) Viktor Posse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human mitochondrial transcription factors TFAM and TFB2M work synergistically in promoter melting during transcription initiation

(2016) Aparna Ramachandran et al.   NUCLEIC ACIDS RESEARCH

Impact of template backbone heterogeneity on RNA polymerase II transcription

(2015) L. Xu et al.   NUCLEIC ACIDS RESEARCH

TEFM is a potent stimulator of mitochondrial transcription elongation in vitro

(2015) Viktor Posse et al.   NUCLEIC ACIDS RESEARCH

Replication-transcription switch in human mitochondria

(2015) K. Agaronyan et al.   SCIENCE

The amino terminal extension of mammalian mitochondrial RNA polymerase ensures promoter specific transcription initiation

(2014) Viktor Posse et al.   NUCLEIC ACIDS RESEARCH

A novel intermediate in transcription initiation by human mitochondrial RNA polymerase

(2014) Yaroslav I. Morozov et al.   NUCLEIC ACIDS RESEARCH

Topoisomerase 1-Mediated Removal of Ribonucleotides from Nascent Leading-Strand DNA

(2013) Jessica S. Williams et al.   MOLECULAR CELL

Ribonucleotides Are Signals for Mismatch Repair of Leading-Strand Replication Errors

(2013) Scott A. Lujan et al.   MOLECULAR CELL

Structure of human mitochondrial RNA polymerase elongation complex

(2013) Kathrin Schwinghammer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Solution Structure of the Dickerson DNA Dodecamer Containing a Single Ribonucleotide

(2012) Eugene F. DeRose et al.   BIOCHEMISTRY

Human mitochondrial RNA polymerase: Structure–function, mechanism and inhibition

(2012) Jamie J. Arnold et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

RNase H2-Initiated Ribonucleotide Excision Repair

(2012) Justin L. Sparks et al.   MOLECULAR CELL

Mammalian transcription factor A is a core component of the mitochondrial transcription machinery

(2012) Y. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribonucleotide Discrimination and Reverse Transcription by the Human Mitochondrial DNA Polymerase

(2011) Rajesh Kasiviswanathan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TEFM (c17orf42) is necessary for transcription of human mtDNA

(2011) Michal Minczuk et al.   NUCLEIC ACIDS RESEARCH

Mutagenic Processing of Ribonucleotides in DNA by Yeast Topoisomerase I

(2011) N. Kim et al.   SCIENCE

Human Mitochondrial Transcription Revisited

(2010) Dmitry Litonin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases

(2010) S. A. Nick McElhinny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TFB2 Is a Transient Component of the Catalytic Site of the Human Mitochondrial RNA Polymerase

(2009) Marina Sologub et al.   CELL

Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro

(2008) S. Wanrooij et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA