(2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice

Eutylone and Its Structural Isomers Interact with Monoamine Transporters and Induce Locomotor Stimulation

(2021) Grant C. Glatfelter et al.   ACS Chemical Neuroscience

First study of safety and tolerability of 3,4-methylenedioxymethamphetamine-assisted psychotherapy in patients with alcohol use disorder

(2021) Ben Sessa et al.   JOURNAL OF PSYCHOPHARMACOLOGY

MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study

(2021) Jennifer M. Mitchell et al.   NATURE MEDICINE

MDMA scores PTSD success in a landmark phase III trial

(2021) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Molecular and clinical aspects of potential neurotoxicity induced by new psychoactive stimulants and psychedelics

(2021) Deborah Rudin et al.   EXPERIMENTAL NEUROLOGY

α-PPP and its derivatives are selective partial releasers at the human norepinephrine transporter

(2021) Julian Maier et al.   NEUROPHARMACOLOGY

Designer drugs: mechanism of action and adverse effects

(2020) Dino Luethi et al.   ARCHIVES OF TOXICOLOGY

Syntheses and analytical characterizations of novel (2‐aminopropyl)benzo[ b ]thiophene (APBT) based stimulants

(2020) Simon D. Brandt et al.   Drug Testing and Analysis

Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species

(2020) Adam L. Halberstadt et al.   NEUROPHARMACOLOGY

Cell-Based Radiotracer Binding and Uptake Inhibition Assays: A Comparison of In Vitro Methods to Assess the Potency of Drugs That Target Monoamine Transporters

(2020) Marija Ilic et al.   Frontiers in Pharmacology

The psychoactive aminoalkylbenzofuran derivatives, 5-APB and 6-APB, mimic the effects of 3,4-methylenedioxyamphetamine (MDA) on monoamine transmission in male rats

(2020) Simon D. Brandt et al.   PSYCHOPHARMACOLOGY

The potential use of N-methyl-3,4-methylenedioxyamphetamine (MDMA) assisted psychotherapy in the treatment of eating disorders comorbid with PTSD

(2020) Timothy D. Brewerton et al.   MEDICAL HYPOTHESES

MDMA-assisted psychotherapy for treatment of anxiety and other psychological distress related to life-threatening illnesses: a randomized pilot study

(2020) Philip E. Wolfson et al.   Scientific Reports

Locomotor activity and discriminative stimulus effects of five novel synthetic cathinone analogs in mice and rats

(2019) Michael B. Gatch et al.   DRUG AND ALCOHOL DEPENDENCE

MDMA-assisted psychotherapy for posttraumatic stress disorder: A promising novel approach to treatment

(2019) Eric Vermetten et al.   NEUROPSYCHOPHARMACOLOGY

Distinct neural mechanisms for the prosocial and rewarding properties of MDMA

(2019) Boris D. Heifets et al.   Science Translational Medicine

Pharmacological profile of mephedrone analogs and related new psychoactive substances

(2018) Dino Luethi et al.   NEUROPHARMACOLOGY

Neurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: high potency agonists at 5-HT2A receptors

(2018) Amy J Eshleman et al.   BIOCHEMICAL PHARMACOLOGY

Effects of repeated treatment with methcathinone, mephedrone, and fenfluramine on intracranial self-stimulation in rats

(2018) J. A. Suyama et al.   PSYCHOPHARMACOLOGY

Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters

(2018) Amy J. Eshleman et al.   PSYCHOPHARMACOLOGY

Clinical applications of hallucinogens: A review.

(2016) Albert Garcia-Romeu et al.   EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY

Electrogenic Binding of Intracellular Cations Defines a Kinetic Decision Point in the Transport Cycle of the Human Serotonin Transporter

(2016) Peter S. Hasenhuetl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Treating posttraumatic stress disorder with MDMA-assisted psychotherapy: A preliminary meta-analysis and comparison to prolonged exposure therapy

(2016) Timothy Amoroso et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The new psychoactive substances 5-(2-aminopropyl)indole (5-IT) and 6-(2-aminopropyl)indole (6-IT) interact with monoamine transporters in brain tissue

(2016) Julie A. Marusich et al.   NEUROPHARMACOLOGY

The hallucinogenic world of tryptamines: an updated review

(2015) Ana Margarida Araújo et al.   ARCHIVES OF TOXICOLOGY

Recent advances in the neuropsychopharmacology of serotonergic hallucinogens

(2015) Adam L. Halberstadt   BEHAVIOURAL BRAIN RESEARCH

Pharmacological profile of novel psychoactive benzofurans

(2015) Anna Rickli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Recreational Use, Analysis and Toxicity of Tryptamines

(2015) Roberta Tittarelli et al.   Current Neuropharmacology

Neurotransmitter and psychostimulant recognition by the dopamine transporter

(2015) Kevin H. Wang et al.   NATURE

Amphetamines, new psychoactive drugs and the monoamine transporter cycle

(2015) Harald H. Sitte et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Patterns of presentation and clinical toxicity after reported use of alpha methyltryptamine in the United Kingdom. A report from the UK National Poisons Information Service

(2014) A. Kamour et al.   CLINICAL TOXICOLOGY

Intoxications of the new psychoactive substance 5-(2-aminopropyl)indole (5-IT): A case series from the Swedish STRIDA project

(2014) M. Bäckberg et al.   CLINICAL TOXICOLOGY

A New Stimulant of Abuse: 5-(2-aminopropyl)indole

(2013) M. Coppola et al.   AMERICAN JOURNAL OF PSYCHIATRY

5-(2-Aminopropyl)indole (5-IT): a psychoactive substance used for recreational purposes is an inhibitor of human monoamine oxidase (MAO)

(2013) Tomás Herraiz et al.   Drug Testing and Analysis

A Cluster of Deaths Involving 5-(2-Aminopropyl)Indole (5-IT)

(2013) R. Kronstrand et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Four Fatalities Involving 5-IT

(2013) L. N. Seetohul et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Characterization of the head-twitch response induced by hallucinogens in mice

(2013) Adam L. Halberstadt et al.   PSYCHOPHARMACOLOGY

Head-twitch response in rodents induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine: a comprehensive history, a re-evaluation of mechanisms, and its utility as a model

(2012) Clint E. Canal et al.   Drug Testing and Analysis

Automated design of ligands to polypharmacological profiles

(2012) Jérémy Besnard et al.   NATURE

Clinical toxicology of newer recreational drugs

(2011) Simon L. Hill et al.   CLINICAL TOXICOLOGY

Unifying Concept of Serotonin Transporter-associated Currents

(2011) Klaus Schicker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhanced effects of amphetamine but reduced effects of the hallucinogen, 5-MeO-DMT, on locomotor activity in 5-HT1A receptor knockout mice: Implications for schizophrenia

(2011) Maarten van den Buuse et al.   NEUROPHARMACOLOGY

The Designer Methcathinone Analogs, Mephedrone and Methylone, are Substrates for Monoamine Transporters in Brain Tissue

(2011) Michael H Baumann et al.   NEUROPSYCHOPHARMACOLOGY

Interaction of 5-HT2A and 5-HT2C Receptors in R(-)-2,5-Dimethoxy-4-iodoamphetamine-Elicited Head Twitch Behavior in Mice

(2010) W. E. Fantegrossi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Differential contributions of serotonin receptors to the behavioral effects of indoleamine hallucinogens in mice

(2010) Adam L Halberstadt et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The safety and efficacy of ±3,4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: the first randomized controlled pilot study

(2010) Michael C Mithoefer et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Serotonergic drugs and valvular heart disease

(2009) Richard B Rothman et al.   Expert Opinion On Drug Safety

5-HT2A and 5-HT2C Receptors Exert Opposing Effects on Locomotor Activity in Mice

(2009) Adam L Halberstadt et al.   NEUROPSYCHOPHARMACOLOGY