Heterogeneity and excitability of BRAF V600E-induced tumors is determined by Akt/mTOR-signaling state and Trp53-loss
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Heterogeneity and excitability of BRAF
V600E-induced tumors is determined by Akt/mTOR-signaling state and Trp53-loss
Authors
Keywords
-
Journal
NEURO-ONCOLOGY
Volume -, Issue -, Pages -
Publisher
Oxford University Press (OUP)
Online
2021-11-30
DOI
10.1093/neuonc/noab268
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Electrical and synaptic integration of glioma into neural circuits
- (2019) Humsa S. Venkatesh et al. NATURE
- Glutamatergic synaptic input to glioma cells drives brain tumour progression
- (2019) Varun Venkataramani et al. NATURE
- Genomic Analysis of Dysembryoplastic Neuroepithelial Tumor Spectrum Reveals a Diversity of Molecular Alterations Dysregulating the MAPK and PI3K/mTOR Pathways
- (2019) Lea F Surrey et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- DEPDC5 and NPRL3 modulate cell size, filopodial outgrowth, and localization of mTOR in neural progenitor cells and neurons
- (2018) Philip H. Iffland et al. NEUROBIOLOGY OF DISEASE
- Dendrite growth and the effect of ectopic Rheb expression on cortical neurons
- (2018) Aidan M. Sokolov et al. NEUROSCIENCE LETTERS
- BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors
- (2018) Hyun Yong Koh et al. NATURE MEDICINE
- FCD Type II and mTOR pathway: Evidence for different mechanisms involved in the pathogenesis of dysmorphic neurons
- (2017) Laura Rossini et al. EPILEPSY RESEARCH
- Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery
- (2017) Ingmar Blumcke et al. NEW ENGLAND JOURNAL OF MEDICINE
- Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway
- (2016) Jason T. Huse et al. ACTA NEUROPATHOLOGICA
- Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology
- (2016) Ibrahim Qaddoumi et al. ACTA NEUROPATHOLOGICA
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Epileptic seizures in anaplastic gangliogliomas
- (2016) Marc Zanello et al. BRITISH JOURNAL OF NEUROSURGERY
- Low-grade epilepsy-associated neuroepithelial tumours — the 2016 WHO classification
- (2016) Ingmar Blümcke et al. Nature Reviews Neurology
- Cortical GABAergic excitation contributes to epileptic activities around human glioma
- (2014) J. Pallud et al. Science Translational Medicine
- Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells
- (2013) Christian Koelsche et al. ACTA NEUROPATHOLOGICA
- Dysembryoplastic Neuroepithelial Tumors Share with Pleomorphic Xanthoastrocytomas and Gangliogliomas BRAFV600EMutation and Expression
- (2013) Céline Chappé et al. BRAIN PATHOLOGY
- BRAF V600E Mutation Is Associated with mTOR Signaling Activation in Glioneuronal Tumors
- (2013) Avanita S. Prabowo et al. BRAIN PATHOLOGY
- Upregulation of mitogen-activated protein kinase in ganglioglioma
- (2013) Beata Rak et al. FOLIA NEUROPATHOLOGICA
- Improved tools for the Brainbow toolbox
- (2013) Dawen Cai et al. NATURE METHODS
- Fate Mapping by PiggyBac Transposase Reveals That Neocortical GLAST+ Progenitors Generate More Astrocytes Than Nestin+ Progenitors in Rat Neocortex
- (2012) F. Siddiqi et al. CEREBRAL CORTEX
- Pediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner
- (2012) A. Kaul et al. GENES & DEVELOPMENT
- Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma
- (2011) Genevieve Schindler et al. ACTA NEUROPATHOLOGICA
- BRAF Activation Induces Transformation and Then Senescence in Human Neural Stem Cells: A Pilocytic Astrocytoma Model
- (2011) E. H. Raabe et al. CLINICAL CANCER RESEARCH
- An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice
- (2011) Jan Gronych et al. JOURNAL OF CLINICAL INVESTIGATION
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- The Neurofibromatosis Type 1 Tumor Suppressor Controls Cell Growth by Regulating Signal Transducer and Activator of Transcription-3 Activity In vitro and In vivo
- (2010) S. Banerjee et al. CANCER RESEARCH
- Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas
- (2010) Margaret J. Dougherty et al. NEURO-ONCOLOGY
- Pi3K-mTOR Signaling and AMOG Expression in Epilepsy-associated Glioneuronal Tumors
- (2009) Karin Boer et al. BRAIN PATHOLOGY
- Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model
- (2009) Sheila Alcantara Llaguno et al. CANCER CELL
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started