Efficacy and safety of larotrectinib in TRK fusion-positive primary central nervous system tumors

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary

(2021) David N Louis et al.   NEURO-ONCOLOGY

Gadolinium is not necessary for surveillance MR imaging in children with chiasmatic‐hypothalamic low‐grade glioma

(2021) Fatema Malbari et al.   PEDIATRIC BLOOD & CANCER

NTRK Fusions in Central Nervous System Tumors: A Rare, but Worthy Target

(2020) Alessandro Gambella et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials

(2020) David S Hong et al.   LANCET ONCOLOGY

Evaluation of RAPNO criteria in medulloblastoma and other leptomeningeal seeding tumors using MRI and clinical data

(2020) Jian Peng et al.   NEURO-ONCOLOGY

Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes

(2020) Matthew Clarke et al.   Cancer Discovery

Pediatric low-grade glioma in the era of molecular diagnostics

(2020) Scott Ryall et al.   Acta Neuropathologica Communications

Response assessment in paediatric low-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group

(2020) Jason Fangusaro et al.   LANCET ONCOLOGY

Response assessment in paediatric high-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group

(2020) Craig Erker et al.   LANCET ONCOLOGY

Molecular and clinicopathologic features of gliomas harboring NTRK fusions

(2020) Matthew Torre et al.   Acta Neuropathologica Communications

Activity of larotrectinib in TRK fusion cancer patients with brain metastases or primary central nervous system tumors.

(2019) Alexander E. Drilon et al.   JOURNAL OF CLINICAL ONCOLOGY

Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas

(2019) Ana S. Guerreiro Stucklin et al.   Nature Communications

Molecularly Targeted Agents in the Therapy of Pediatric Brain Tumors

(2019) Miriam Bornhorst et al.   PEDIATRIC DRUGS

Targetable Gene Fusions Associate With the IDH Wild-Type Astrocytic Lineage in Adult Gliomas

(2018) Sherise D Ferguson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

DNA methylation-based classification of central nervous system tumours

(2018) David Capper et al.   NATURE

Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children

(2018) Alexander Drilon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma

(2018) David S. Ziegler et al.   BRITISH JOURNAL OF CANCER

Molecular characterization of cancers with NTRK gene fusions

(2018) Zoran Gatalica et al.   MODERN PATHOLOGY

NTRK fusion-positive cancers and TRK inhibitor therapy

(2018) Emiliano Cocco et al.   Nature Reviews Clinical Oncology

TRK Inhibition: A New Tumor-Agnostic Treatment Strategy

(2018) Shivaani Kummar et al.   Targeted Oncology

Response Assessment in Neuro-Oncology Clinical Trials

(2017) Patrick Y. Wen et al.   JOURNAL OF CLINICAL ONCOLOGY

High-grade glioma in very young children: a rare and particular patient population

(2017) Moatasem El-Ayadi et al.   Oncotarget

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

(2014) Gang Wu et al.   NATURE GENETICS

The landscape of kinase fusions in cancer

(2014) Nicolas Stransky et al.   Nature Communications

TRKing Down an Old Oncogene in a New Era of Targeted Therapy

(2014) Aria Vaishnavi et al.   Cancer Discovery

Updated Response Assessment Criteria for High-Grade Gliomas: Response Assessment in Neuro-Oncology Working Group

(2010) Patrick Y. Wen et al.   JOURNAL OF CLINICAL ONCOLOGY

Current Treatment Approaches for Infants with Malignant Central Nervous System Tumors

(2009) L. Lafay-Cousin et al.   ONCOLOGIST

New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)

(2008) E.A. Eisenhauer et al.   EUROPEAN JOURNAL OF CANCER