The structural basis of PTEN regulation by multi-site phosphorylation
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Title
The structural basis of PTEN regulation by multi-site phosphorylation
Authors
Keywords
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Journal
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 28, Issue 10, Pages 858-868
Publisher
Springer Science and Business Media LLC
Online
2021-10-10
DOI
10.1038/s41594-021-00668-5
References
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- (2011) Makoto Matsuda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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