Review
Gastroenterology & Hepatology
Iulia Minciuna, Suchira Gallage, Mathias Heikenwalder, Shira Zelber-Sagi, Jean-Francois Dufour
Summary: NASH, a chronic liver disease that can progress to end-stage liver disease and HCC, can be effectively treated with intermittent fasting, which not only induces weight loss but also reduces inflammation and oxidative stress.
Article
Nutrition & Dietetics
Bo-Ying Zang, Li-Xia He, Ling Xue
Summary: Obesity and diabetes are significant health issues, and moderate weight loss is important for reducing the risk of metabolic diseases. Intermittent fasting (IF) is a popular weight loss strategy, but more research is needed, especially regarding its application in obese and type 2 diabetic patients.
Article
Biotechnology & Applied Microbiology
Xiangwei Hu, Kai Xia, Minhui Dai, Xiaofeng Han, Peng Yuan, Jia Liu, Shiwei Liu, Fuhuai Jia, Jiayu Chen, Fangfang Jiang, Jieyao Yu, Huanming Yang, Jian Wang, Xun Xu, Xin Jin, Karsten Kristiansen, Liang Xiao, Wei Chen, Mo Han, Shenglin Duan
Summary: Intermittent fasting is a promising weight loss method that modulates the gut microbiota. A three-week IF program resulted in an average weight loss of 3.67 kg and improved clinical parameters, regardless of initial BMI and gut microbiota status.
NPJ BIOFILMS AND MICROBIOMES
(2023)
Review
Nutrition & Dietetics
Juliette Frank, Arpana Gupta, Vadim Osadchiy, Emeran A. Mayer
Summary: The obesity epidemic and its metabolic consequences are a significant public health issue, with dysregulations within the brain-gut-microbiome (BGM) system playing a central role. The balance between homeostatic and hedonic eating behaviors is disrupted by the availability and marketing of inexpensive, calorie-dense foods. Eating behavior is not only influenced by diet composition and amount, but also by timing and rhythmicity of food ingestion.
Review
Medicine, General & Internal
Mohammed Allaf, Hussein Elghazaly, Omer G. Mohamed, Mohamed Firas Khan Fareen, Sadia Zaman, Abdul-Majeed Salmasi, Kostas Tsilidis, Abbas Dehghan
Summary: Cardiovascular disease is a leading cause of death globally, with lifestyle changes like increased physical activity and healthy diets being key for prevention. Intermittent fasting has shown some benefits and is being researched for its role in reducing the risk of CVD.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Immunology
Mehdi Barati, Amirali Ghahremani, Hasan Namdar Ahmadabad
Summary: Intermittent fasting has potential benefits for autoimmune diseases by reducing inflammation, modulating the immune system, improving gut microbiota, and enhancing cellular repair mechanisms. However, evidence on its effects for certain autoimmune diseases such as multiple sclerosis, systemic lupus erythematosus, thyroid diseases, and psoriasis is limited and inconclusive. Further research is needed to determine optimal intermittent fasting guidelines and long-term effects on autoimmune diseases.
AUTOIMMUNITY REVIEWS
(2023)
Article
Nutrition & Dietetics
Ronaldo Angelo Dias da Silva, Leszek Antoni Szmuchrowski, Joao Paulo Pereira Rosa, Marcos Antonio Pereira dos Santos, Marco Tulio de Mello, Lucas Savoi, Yves Ferreira Porto, Francisco de Assis Dias Martins, Marcos Daniel Motta Drummond
Summary: Intermittent fasting (IF) is commonly used by combat sports athletes for weight loss but may decrease performance. This study examined the effects of IF on body weight and Taekwondo performance. The results showed that IF led to a decrease in body weight in the first two weeks but stabilized afterwards. Performance in vertical jumping had different patterns in fed and fasted states. Despite the decrease in body weight, IF did not significantly impact performance.
Review
Environmental Sciences
Nur Izzah Hamna A. Aziz, Marlia M. Hanafiah
Summary: In recent years, there has been a growing focus on the sustainability performance of desalination processes, particularly seawater reverse osmosis. While previous studies have mainly assessed environmental performance, future research should pay more attention to the economic and social aspects of desalination technology.
ENVIRONMENTAL POLLUTION
(2021)
Article
Nutrition & Dietetics
Mohammad Taghi Najafi, Ali Sadoogh Abbasian, Hamed Mohammadi, Mohammad Reza Abbasi, Mohammad Reza Khatami, Ali Ghafari, Mohammad Hossein Shojamoradi
Summary: This study aimed to assess the changes in body water compartment and composition during Ramadan fasting. The results showed that there was a significant weight loss after fasting, primarily due to the reduction in fat mass. The decrease in intracellular water indicated impaired cell membrane integrity and movement of water from the intracellular to the extracellular compartment.
FRONTIERS IN NUTRITION
(2023)
Review
Nutrition & Dietetics
Kelsey Gabel, Kate Cares, Krista Varady, Vijayakrishna Gadi, Lisa Tussing-Humphreys
Summary: Intermittent fasting shows potential in improving chemotherapy effectiveness, reducing treatment-related side effects, and ameliorating decreases in quality of life and daily functioning during chemotherapy.
ADVANCES IN NUTRITION
(2022)
Review
Medicine, General & Internal
Chanthawat Patikorn, Kiera Roubal, Sajesh K. Veettil, Viji Chandran, Tuan Pham, Yeong Yeh Lee, Edward L. Giovannucci, Krista A. Varady, Nathorn Chaiyakunapruk
Summary: This study reviewed the evidence from multiple meta-analyses of randomized clinical trials on the associations of intermittent fasting with obesity-related health outcomes. The findings showed beneficial effects of intermittent fasting on anthropometric and cardiometabolic outcomes, supported by moderate to high quality evidence.
Review
Gastroenterology & Hepatology
Marcia Lange, Devika Nadkarni, Lily Martin, Carolyn Newberry, Sonal Kumar, Tatyana Kushner
Summary: Despite the lack of FDA-approved treatments for NAFLD, intermittent fasting shows promising results in improving hepatic endpoints and promoting weight loss in adults with NAFLD. However, further large-scale randomized controlled studies are needed to validate these findings.
HEPATOLOGY COMMUNICATIONS
(2023)
Review
Gastroenterology & Hepatology
Marcia Lange, Devika Nadkarni, Lily Martin, Carolyn Newberry, Sonal Kumar, Tatyana Kushner
Summary: Despite the lack of FDA-approved treatments for NAFLD, intermittent fasting (IF) has shown promising results in improving hepatic end points and promoting weight loss in adults with NAFLD. This systematic review and meta-analysis found moderate- to high-quality evidence suggesting that IF can significantly improve body weight, body mass index, waist to hip ratio, serum alanine transaminase, aspartate aminotransferase, hepatic steatosis, and hepatic stiffness in NAFLD patients. However, larger randomized controlled studies with extended duration are needed for further validation.
HEPATOLOGY COMMUNICATIONS
(2023)
Article
Endocrinology & Metabolism
Maura Fanti, Amrendra Mishra, Valter D. Longo, Sebastian Brandhorst
Summary: Dietary interventions, such as time-restricted eating, intermittent fasting, and fasting-mimicking diets, have shown potential for weight loss, but long-term efficacy remains uncertain and requires further research to validate.
CURRENT OBESITY REPORTS
(2021)
Review
Nutrition & Dietetics
Heitor O. Santos, Rafael Genario, Grant M. Tinsley, Poliana Ribeiro, Randhall B. Carteri, Christianne De Faria Coelho-Ravagnani, Joao F. Mota
Summary: Intermittent fasting (IF) is a flexible dietary strategy that can improve metabolism and clinical nutrition through delayed or early eating windows. However, current evidence suggests that IF is not more effective than traditional diets at the group level, and its effects are mainly dependent on energy restriction. Therefore, individual dietary prescriptions should be based on patient's biological rhythms, preferences, and medical conditions in clinical practice.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)