A fresh look at coronary microembolization

Microthrombi As A Major Cause of Cardiac Injury in COVID-19: A Pathologic Study

(2021) Dario Pellegrini et al.   CIRCULATION

New Insights Into Plaque Erosion as a Mechanism of Acute Coronary Syndromes

(2021) Dhaval Kolte et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Puerarin pretreatment attenuates cardiomyocyte apoptosis induced by coronary microembolization in rats by activating the PI3K/Akt/GSK-3β signaling pathway

(2021) Zhi-Qing Chen et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Breviscapine Pretreatment Inhibits Myocardial Inflammation and Apoptosis in Rats After Coronary Microembolization by Activating the PI3K/Akt/GSK-3β Signaling Pathway

(2021) Zhi-Qing Chen et al.   Drug Design Development and Therapy

Protective effect of glycyrrhizin on coronary microembolization‐induced myocardial dysfunction in rats

(2021) Yonggang Yuan et al.   Pharmacology Research & Perspectives

Treatment Effects of Interleukin-6 Receptor Antibodies for Modulating the Systemic Inflammatory Response After Out-of-Hospital Cardiac Arrest (The IMICA Trial)

(2021) Martin Abild Stengaard Meyer et al.   CIRCULATION

Colchicine to Prevent Periprocedural Myocardial Injury in Percutaneous Coronary Intervention: The COPE-PCI Pilot Trial

(2021) Justin Cole et al.   Circulation-Cardiovascular Interventions

Oral Antiplatelet Therapy After Acute Coronary Syndrome

(2021) Hassan Kamran et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction

(2021) Kaspar Broch et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The changing landscape of atherosclerosis

(2021) Peter Libby   NATURE

Plaque erosion and acute coronary syndromes: phenotype, molecular characteristics and future directions

(2021) Akl C. Fahed et al.   Nature Reviews Cardiology

Interplay between inflammation and thrombosis in cardiovascular pathology

(2021) Konstantin Stark et al.   Nature Reviews Cardiology

Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants

(2021) Julian U. G. Wagner et al.   BASIC RESEARCH IN CARDIOLOGY

Culprit site extracellular DNA and microvascular obstruction in ST-elevation myocardial infarction

(2021) Andreas Mangold et al.   CARDIOVASCULAR RESEARCH

Prognostically relevant periprocedural myocardial injury and infarction associated with percutaneous coronary interventions: a Consensus Document of the ESC Working Group on Cellular Biology of the Heart and European Association of Percutaneous Cardiovascular Interventions (EAPCI)

(2021) Heerajnarain Bulluck et al.   EUROPEAN HEART JOURNAL

Overexpression of lncRNA TUG1 Alleviates NLRP3 Inflammasome-Mediated Cardiomyocyte Pyroptosis Through Targeting the miR-186-5p/XIAP Axis in Coronary Microembolization-Induced Myocardial Damage

(2021) You Zhou et al.   Frontiers in Immunology

miR-200a-3p Attenuates Coronary Microembolization-Induced Myocardial Injury in Rats by Inhibiting TXNIP/NLRP3-Mediated Cardiomyocyte Pyroptosis

(2021) Zhi-Qing Chen et al.   Frontiers in Cardiovascular Medicine

Long-term outcome after thrombus aspiration in non-ST-elevation myocardial infarction: results from the TATORT-NSTEMI trial

(2020) Hans-Josef Feistritzer et al.   Clinical Research in Cardiology

Effects of Acute Colchicine Administration Prior to Percutaneous Coronary Intervention

(2020) Binita Shah et al.   Circulation-Cardiovascular Interventions

Endothelial cell infection and endotheliitis in COVID-19

(2020) Zsuzsanna Varga et al.   LANCET

Myocardial ischaemia–reperfusion injury and cardioprotection in perspective

(2020) Gerd Heusch   Nature Reviews Cardiology

Myocarditis is rare in COVID-19 autopsies: Cardiovascular findings across 277 post-mortem examinations

(2020) Marc K. Halushka et al.   CARDIOVASCULAR PATHOLOGY

2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation

(2020) Jean-Philippe Collet et al.   EUROPEAN HEART JOURNAL

Pathological features of COVID-19-associated myocardial injury: a multicentre cardiovascular pathology study

(2020) Cristina Basso et al.   EUROPEAN HEART JOURNAL

Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap: results from the prospective translational OPTICO-ACS study

(2020) David M Leistner et al.   EUROPEAN HEART JOURNAL

Role of Cardiac Biomarkers in Epidemiology and Risk Outcomes

(2020) Paul M Haller et al.   CLINICAL CHEMISTRY

Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation

(2020) Sean X. Gu et al.   Nature Reviews Cardiology

Assessment of Neutrophil Extracellular Traps in Coronary Thrombus of a Case Series of Patients With COVID-19 and Myocardial Infarction

(2020) Ana Blasco et al.   JAMA Cardiology

Reassessing the Mechanisms of Acute Coronary Syndromes

(2019) Peter Libby et al.   CIRCULATION RESEARCH

Effect of Low-Dose Intracoronary Alteplase During Primary Percutaneous Coronary Intervention on Microvascular Obstruction in Patients With Acute Myocardial Infarction

(2019) Peter J. McCartney et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Routine Glycoprotein IIb/IIIa Inhibitor Therapy in ST-Segment Elevation Myocardial Infarction: A Meta-Analysis

(2019) Athanasios Karathanos et al.   CANADIAN JOURNAL OF CARDIOLOGY

Resveratrol Attenuates Cardiomyocyte Apoptosis in Rats Induced by Coronary Microembolization Through SIRT1-Mediated Deacetylation of p53

(2019) Qing Mao et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Nobiletin protects against myocardial injury and myocardial apoptosis following coronary microembolization via activating PI3K/Akt pathway in rats

(2019) Qing Mao et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Optimized Treatment of ST-Elevation Myocardial Infarction

(2019) Giampaolo Niccoli et al.   CIRCULATION RESEARCH

Intravenous Statin Administration During Ischemia Exerts Cardioprotective Effects

(2019) Guiomar Mendieta et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Low Dose Colchicine after Myocardial Infarction (LoDoCo-MI) study: A pilot randomized placebo controlled trial of colchicine following acute myocardial infarction

(2019) Thomas Hennessy et al.   AMERICAN HEART JOURNAL

Ticagrelor or Prasugrel in Patients with Acute Coronary Syndromes

(2019) Stefanie Schüpke et al.   NEW ENGLAND JOURNAL OF MEDICINE

Coronary microvascular obstruction: the new frontier in cardioprotection

(2019) Gerd Heusch   BASIC RESEARCH IN CARDIOLOGY

What Are Optimal P2Y12 Inhibitor and Schedule of Administration in Patients With Acute Coronary Syndrome?

(2019) Michael V. Cohen et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Interleukin-1β Mediates Arterial Thrombus Formation via NET-Associated Tissue Factor

(2019) Luca Liberale et al.   Journal of Clinical Medicine

Plaque erosion: a new in vivo diagnosis and a potential major shift in the management of patients with acute coronary syndromes

(2018) Ramon A Partida et al.   EUROPEAN HEART JOURNAL

OUP accepted manuscript

(2018)   EUROPEAN HEART JOURNAL

Coronary Embolus

(2018) Claire E. Raphael et al.   JACC-Cardiovascular Interventions

A Randomized Study of Distal Filter Protection Versus Conventional Treatment During Percutaneous Coronary Intervention in Patients With Attenuated Plaque Identified by Intravascular Ultrasound

(2018) Kiyoshi Hibi et al.   JACC-Cardiovascular Interventions

Fourth Universal Definition of Myocardial Infarction (2018)

(2018) Kristian Thygesen et al.   CIRCULATION

Vago-Splenic Axis in Signal Transduction of Remote Ischemic Preconditioning in Pigs and Rats

(2018) Helmut Raphael Lieder et al.   CIRCULATION RESEARCH

Impact of direct stenting on myocardial injury assessed by cardiac magnetic resonance imaging and prognosis in ST-elevation myocardial infarction

(2018) Mohammed Saad et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Relationship between microvascular obstruction and adverse events following primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: an individual patient data pooled analysis from seven randomized trials

(2017) Suzanne de Waha et al.   EUROPEAN HEART JOURNAL

2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation

(2017) Borja Ibanez et al.   EUROPEAN HEART JOURNAL

2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS

(2017) Marco Valgimigli et al.   EUROPEAN HEART JOURNAL

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Remote ischaemic preconditioning reduces myocardial ischaemic reperfusion injury in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention

(2016) Zhen-bing Liu et al.   ACTA CARDIOLOGICA

Establishment of a Novel Mouse Model of Coronary Microembolization

(2016) Ju-Ying Qian et al.   CHINESE MEDICAL JOURNAL

The Coronary Circulation as a Target of Cardioprotection

(2016) Gerd Heusch   CIRCULATION RESEARCH

Strategies to attenuate micro-vascular obstruction during P-PCI: the randomized reperfusion facilitated by local adjunctive therapy in ST-elevation myocardial infarction trial

(2016) Sheraz A. Nazir et al.   EUROPEAN HEART JOURNAL

Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial

(2016) Ola Kleveland et al.   EUROPEAN HEART JOURNAL

Clinical benefit of adenosine as an adjunct to reperfusion in ST-elevation myocardial infarction patients: An updated meta-analysis of randomized controlled trials

(2016) Heerajnarain Bulluck et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Thrombus Aspiration in Patients With ST-Segment Elevation Myocardial Infarction Presenting Late After Symptom Onset

(2016) Steffen Desch et al.   JACC-Cardiovascular Interventions

Quantification and characterisation of released plaque material during bioresorbable vascular scaffold implantation into right coronary artery lesions by multimodality intracoronary imaging

(2016) Heike Hildebrandt et al.   EuroIntervention

Trimetazidine Pretreatment Inhibits Myocardial Apoptosis and Improves Cardiac Function in a Swine Model of Coronary Microembolization

(2015) Yang-Chun Liu et al.   CARDIOLOGY

Anti-Inflammatory Treatment With Colchicine in Acute Myocardial InfarctionClinical Perspective

(2015) Spyridon Deftereos et al.   CIRCULATION

Across-Species Transfer of Protection by Remote Ischemic Preconditioning With Species-Specific Myocardial Signal Transduction by Reperfusion Injury Salvage Kinase and Survival Activating Factor Enhancement PathwaysNovelty and Significance

(2015) Andreas Skyschally et al.   CIRCULATION RESEARCH

Cardioprotection by combined intrahospital remote ischaemic perconditioning and postconditioning in ST-elevation myocardial infarction: the randomized LIPSIA CONDITIONING trial

(2015) Ingo Eitel et al.   EUROPEAN HEART JOURNAL

Plaque Characterization to Inform the Prediction and Prevention of Periprocedural Myocardial Infarction During Percutaneous Coronary Intervention

(2015) Gregg W. Stone et al.   JACC-Cardiovascular Interventions

Remote Ischemic Conditioning Reduces Myocardial Infarct Size and Edema in Patients With ST-Segment Elevation Myocardial Infarction

(2015) Steven K. White et al.   JACC-Cardiovascular Interventions

Randomized Trial of Primary PCI with or without Routine Manual Thrombectomy

(2015) Sanjit S. Jolly et al.   NEW ENGLAND JOURNAL OF MEDICINE

Colchicine Acutely Suppresses Local Cardiac Production of Inflammatory Cytokines in Patients With an Acute Coronary Syndrome

(2015) Gonzalo J. Martínez et al.   Journal of the American Heart Association

Release of Intracoronary Microparticles during Stent Implantation into Stable Atherosclerotic Lesions under Protection with an Aspiration Device

(2015) Patrick Horn et al.   PLoS One

The effect of interleukin-1 receptor antagonist therapy on markers of inflammation in non-ST elevation acute coronary syndromes: the MRC-ILA Heart Study

(2014) A. C. Morton et al.   EUROPEAN HEART JOURNAL

Remote ischemic preconditioning reduces peri-procedural myocardial injury in elective percutaneous coronary intervention: A meta-analysis

(2014) Theodoros A. Zografos et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Aspirate from human stented native coronary arteries vs. saphenous vein grafts: more endothelin but less particulate debris

(2013) Petra Kleinbongard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Remote Ischemic Preconditioning Reduces Myocardial Injury in Patients Undergoing Coronary Stent Implantation

(2013) Sheng Jie Luo et al.   CANADIAN JOURNAL OF CARDIOLOGY

Coronary aspirate TNFα reflects saphenous vein bypass graft restenosis risk in diabetic patients

(2013) Theodor Baars et al.   Cardiovascular Diabetology

The Regional Myocardial Flow–Function Relationship

(2013) Gerd Heusch   CIRCULATION RESEARCH

Remote Ischemic Preconditioning Improves Outcome at 6 Years After Elective Percutaneous Coronary Intervention

(2013) William R. Davies et al.   Circulation-Cardiovascular Interventions

Fingerprints of periprocedural coronary microembolization on multimodality intravascular imaging

(2013) H.A. Hildebrandt et al.   HERZ

Remote Ischemic Post-Conditioning of the Lower Limb During Primary Percutaneous Coronary Intervention Safely Reduces Enzymatic Infarct Size in Anterior Myocardial Infarction

(2013) Gabriele Crimi et al.   JACC-Cardiovascular Interventions

Open-Label, Randomized, Placebo-Controlled Evaluation of Intracoronary Adenosine or Nitroprusside After Thrombus Aspiration During Primary Percutaneous Coronary Intervention for the Prevention of Microvascular Obstruction in Acute Myocardial Infarction

(2013) Giampaolo Niccoli et al.   JACC-Cardiovascular Interventions

Effects of the P-Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention for Non–ST-Segment Elevation Myocardial Infarction

(2013) Jean-Claude Tardif et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Thrombus Aspiration during ST-Segment Elevation Myocardial Infarction

(2013) Ole Fröbert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Saphenous vein aorto-coronary graft atherosclerosis in patients with chronic kidney disease: more plaque calcification and necrosis, but less vasoconstrictor potential

(2012) Theodor Baars et al.   BASIC RESEARCH IN CARDIOLOGY

Microembolization and myonecrosis during elective percutaneous coronary interventions in diabetic patients: an intracoronary Doppler ultrasound study with 2-year clinical follow-up

(2012) Sylvia Otto et al.   BASIC RESEARCH IN CARDIOLOGY

Remote ischemic preconditioning immediately before percutaneous coronary intervention does not impact myocardial necrosis, inflammatory response, and circulating endothelial progenitor cell counts: A single center randomized sham controlled trial

(2012) Abhiram Prasad et al.   CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

Coronary microembolization during early reperfusion: infarct extension, but protection by ischaemic postconditioning

(2012) A. Skyschally et al.   EUROPEAN HEART JOURNAL

A Prospective Randomized Trial of Thrombectomy Versus No Thrombectomy in Patients With ST-Segment Elevation Myocardial Infarction and Thrombus-Rich Lesions

(2012) Marco De Carlo et al.   JACC-Cardiovascular Interventions

Intracoronary Abciximab and Aspiration Thrombectomy in Patients With Large Anterior Myocardial Infarction

(2012) Gregg W. Stone   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Platelet P2Y12 Blockers Confer Direct Postconditioning-Like Protection in Reperfused Rabbit Hearts

(2012) Xi-Ming Yang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Histological correlate of a cardiac magnetic resonance imaged microvascular obstruction in a porcine model of ischemia–reperfusion

(2011) Ronald B. Driesen et al.   CARDIOVASCULAR PATHOLOGY

β-Adrenergic receptor blockade reduces endoplasmic reticulum stress and normalizes calcium handling in a coronary embolization model of heart failure in canines

(2011) Isaac George et al.   CARDIOVASCULAR RESEARCH

Aspiration coronary thrombectomy for acute myocardial infarction increases myocardial salvage

(2011) Michał Ciszewski et al.   CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

Clinical Benefit of Statin Pretreatment in Patients Undergoing Percutaneous Coronary Intervention

(2011) Giuseppe Patti et al.   CIRCULATION

Peri-interventional coronary vasomotion

(2011) Luisa Gregorini et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Lessons from human coronary aspirate

(2011) Petra Kleinbongard et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Evaluation of the acute effects of distal coronary microembolization using multidetector computed tomography and magnetic resonance imaging

(2011) Maythem Saeed et al.   MAGNETIC RESONANCE IN MEDICINE

Coronary microembolization causes long-term detrimental effects on regional left ventricular function

(2011) Marcus Carlsson et al.   SCANDINAVIAN CARDIOVASCULAR JOURNAL

Thrombus aspiration followed by direct stenting: A novel strategy of primary percutaneous coronary intervention in ST-segment elevation myocardial infarction. Results of the Polish-Italian-Hungarian RAndomized ThrombEctomy Trial (PIHRATE Trial)

(2010) Dariusz Dudek et al.   AMERICAN HEART JOURNAL

The Role of ERK1/2 Signaling Pathway in Coronary Microembolization-Induced Rat Myocardial Inflammation and Injury

(2010) Lang Li et al.   CARDIOLOGY

Vasoconstrictor Potential of Coronary Aspirate From Patients Undergoing Stenting of Saphenous Vein Aortocoronary Bypass Grafts and Its Pharmacological Attenuation

(2010) Petra Kleinbongard et al.   CIRCULATION RESEARCH

Peri-procedural myocardial injury during percutaneous coronary intervention: an important target for cardioprotection

(2010) G. Ganesha Babu et al.   EUROPEAN HEART JOURNAL

Comparison of AngioJet Rheolytic Thrombectomy Before Direct Infarct Artery Stenting With Direct Stenting Alone in Patients With Acute Myocardial Infarction

(2010) Angela Migliorini et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Altered expression of pro- and anti-inflammatory cytokines is associated with reduced cardiac function in rats following coronary microembolization

(2010) Lang Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Blockade of NF-κB by pyrrolidine dithiocarbamate attenuates myocardial inflammatory response and ventricular dysfunction following coronary microembolization induced by homologous microthrombi in rats

(2009) Shumei Li et al.   BASIC RESEARCH IN CARDIOLOGY

Coronary Microembolization

(2009) Gerd Heusch et al.   CIRCULATION

Prognostic value of coronary revascularisation-related myocardial injury: a cardiac magnetic resonance imaging study

(2009) K Rahimi et al.   HEART

Randomized Comparison of Primary Percutaneous Coronary Intervention With Combined Proximal Embolic Protection and Thrombus Aspiration Versus Primary Percutaneous Coronary Intervention Alone in ST-Segment Elevation Myocardial Infarction

(2009) Joost D.E. Haeck et al.   JACC-Cardiovascular Interventions

Efficacy of Atorvastatin Reload in Patients on Chronic Statin Therapy Undergoing Percutaneous Coronary Intervention

(2009) Germano Di Sciascio et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Microemboli and Microvascular Obstruction in Acute Coronary Thrombosis and Sudden Coronary Death

(2009) Robert S. Schwartz et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Thrombus Aspiration During Primary Percutaneous Coronary Intervention Improves Myocardial Reperfusion and Reduces Infarct Size

(2009) Gennaro Sardella et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Myocardial Microinfarction after Coronary Microembolization in Swine: MR Imaging Characterization

(2009) Marcus Carlsson et al.   RADIOLOGY

Systematic Analysis of Functional and Structural Changes After Coronary Microembolization: A Cardiac Magnetic Resonance Imaging Study

(2009) Frank Breuckmann et al.   JACC-Cardiovascular Imaging

Impact of atherosclerotic plaque composition on coronary microembolization during percutaneous coronary interventions

(2008) Dirk Böse et al.   BASIC RESEARCH IN CARDIOLOGY

Reduced calcium responsiveness characterizes contractile dysfunction following coronary microembolization

(2008) Andreas Skyschally et al.   BASIC RESEARCH IN CARDIOLOGY

A Novel Filter-Based Distal Embolic Protection Device for Percutaneous Intervention of Saphenous Vein Graft Lesions

(2008) Dean J. Kereiakes et al.   JACC-Cardiovascular Interventions

Randomized Comparison of Distal Protection Versus Conventional Treatment in Primary Percutaneous Coronary Intervention

(2008) Henning Kelbæk et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Direct Stenting for Stable Angina Pectoris Is Associated With Reduced Periprocedural Microcirculatory Injury Compared With Stenting After Pre-Dilation

(2008) Thomas Cuisset et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Thrombus Aspiration during Primary Percutaneous Coronary Intervention

(2008) Tone Svilaas et al.   NEW ENGLAND JOURNAL OF MEDICINE

How Much Myocardial Damage Is Necessary to Enable Detection of Focal Late Gadolinium Enhancement at Cardiac MR Imaging?

(2008) Kai Nassenstein et al.   RADIOLOGY

Distal protection device protects microvascular integrity during primary percutaneous intervention in acute myocardial infarction: A prospective, randomized, multicenter trial

(2007) Seung-Jea Tahk et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY