Exocytosis blockade of endoplasmic reticulum-targeted nanoparticle enhances immunotherapy

Key principles and methods for studying the endocytosis of biological and nanoparticle therapeutics

(2021) Joshua J. Rennick et al.   Nature Nanotechnology

Intratumoral immunotherapy using platelet-cloaked nanoparticles enhances antitumor immunity in solid tumors

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Inhibition of Immunosuppressive Tumors by Polymer‐Assisted Inductions of Immunogenic Cell Death and Multivalent PD‐L1 Crosslinking

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Endoplasmic Reticulum Targeting to Amplify Immunogenic Cell Death for Cancer Immunotherapy

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Pharmaceutical strategies for endoplasmic reticulum-targeting and their prospects of application

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Regulating intracellular fate of siRNA by endoplasmic reticulum membrane-decorated hybrid nanoplexes

(2019) Chong Qiu et al.   Nature Communications

Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death

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Multifunctional Nanoparticles Enable Efficient Oral Delivery of Biomacromolecules via Improving Payload Stability and Regulating the Transcytosis Pathway

(2018) Yaxian Zheng et al.   ACS Applied Materials & Interfaces

Pathways of Unconventional Protein Secretion

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Cancer Cell Membrane–Biomimetic Nanoparticles for Homologous-Targeting Dual-Modal Imaging and Photothermal Therapy

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Cancer Cell Membrane-Coated Upconversion Nanoprobes for Highly Specific Tumor Imaging

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Preferential Cancer Cell Self-Recognition and Tumor Self-Targeting by Coating Nanoparticles with Homotypic Cancer Cell Membranes

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BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression

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Nanoparticle biointerfacing by platelet membrane cloaking

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Inducible but Not Constitutive Expression of PD-L1 in Human Melanoma Cells Is Dependent on Activation of NF-κB

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Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery

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Crosstalk between ER stress and immunogenic cell death

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Organization of the ER–Golgi interface for membrane traffic control

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Galectin-3 increases the motility of mouse melanoma cells by regulating matrix metalloproteinase-1 expression

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Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation

(2012) Yueguang Rong et al.   NATURE CELL BIOLOGY

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

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Erythrocyte-Inspired Delivery Systems

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Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform

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Uptake and trafficking of liposomes to the endoplasmic reticulum

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Endoplasmic reticulum aminopeptidases: biology and pathogenic potential

(2010) Nigil Haroon et al.   Nature Reviews Rheumatology

Reduced endoplasmic reticulum (ER)-to-Golgi protein trafficking contributes to ER stress in lipotoxic mouse beta cells by promoting protein overload

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A Golgi-on-a-chip for glycan synthesis

(2009) Ding Xu et al.   Nature Chemical Biology

Targeted killing of colorectal cancer cell lines by a humanised IgG1 monoclonal antibody that binds to membrane-bound carcinoembryonic antigen

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A syntaxin 10–SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells

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A traffic-activated Golgi-based signalling circuit coordinates the secretory pathway

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