Use of Polyhedral Oligomeric Silsesquioxane (POSS) in Drug Delivery, Photodynamic Therapy and Bioimaging

Molecular Dynamic Simulation of Polyhedral Oligomeric Silsesquioxane Porphyrin Molecules: Self-assembly and Influence on Morphology

(2021) Paula Loman-Cortes et al.   Materials Today Communications

Peptide 18-4/chlorin e6-conjugated polyhedral oligomeric silsesquioxane nanoparticles for targeted photodynamic therapy of breast cancer

(2020) Ye-Ji Kim et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Polyhedral Oligomeric Silsesquioxanes ( POSS )‐based Hybrid Materials: Molecular Design, Solution Self‐Assembly and Biomedical Applications

(2020) Linfeng Fan et al.   CHINESE JOURNAL OF CHEMISTRY

POSS hybrid hydrogels: A brief review of synthesis, properties and applications

(2020) Siju Liu et al.   EUROPEAN POLYMER JOURNAL

Silsesquioxane-Containing Hybrid Nanomaterials: Fascinating Platforms for Advanced Applications

(2019) Fuping Dong et al.   MACROMOLECULAR CHEMISTRY AND PHYSICS

Multimodal Polysilsesquioxane Nanoparticles for Combinatorial Therapy and Gene Delivery in Triple-Negative Breast Cancer

(2019) Ridhima Juneja et al.   ACS Applied Materials & Interfaces

Polyhedral Oligomeric Silsesquioxane Hybrid Polymers: Well‐Defined Architectural Design and Potential Functional Applications

(2019) Fang Chen et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Daunorubicin-silsesquioxane conjugates (POSS-DAU) for theranostic drug delivery system: Characterization, biocompatibility and drug release study

(2019) Krystyna Rozga-Wijas et al.   REACTIVE & FUNCTIONAL POLYMERS

Simultaneous improvement in toughness, strength and biocompatibility of poly(lactic acid) with polyhedral oligomeric silsesquioxane

(2018) Zhibin Liu et al.   CHEMICAL ENGINEERING JOURNAL

Development of a Light-Controlled Nanoplatform for Direct Nuclear Delivery of Molecular and Nanoscale Materials

(2018) Ya-Xuan Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multitargeting Peptide-Functionalized Star-Shaped Copolymers with Comblike Structure and a POSS-Core To Effectively Transfect Endothelial Cells

(2018) Jun Wang et al.   ACS Biomaterials-Science & Engineering

Recent Development of Inorganic Nanoparticles for Biomedical Imaging

(2018) Dokyoon Kim et al.   ACS Central Science

Multitargeting Peptide-Functionalized Star-Shaped Copolymers with Comblike Structure and a POSS-Core To Effectively Transfect Endothelial Cells

(2018) Jun Wang et al.   ACS Biomaterials Science & Engineering

Polyhedral Oligomeric Silsesquioxane (POSS)-Based Cationic Conjugated Oligoelectrolyte/Porphyrin for Efficient Energy Transfer and Multiamplified Antimicrobial Activity

(2018) Jia Chen et al.   ACS Applied Materials & Interfaces

Polyhedral octasilsesquioxanes labelled with the photosensitive cationic phenosafranin dye as a new nanocarrier for therapy and cellular imaging

(2018) Krystyna Rozga-Wijas et al.   DYES AND PIGMENTS

Enhancing the Efficacy of Photodynamic Therapy through a Porphyrin/POSS Alternating Copolymer

(2018) Jianqiu Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis, characterization and thermal properties of T 8 type amido-POSS with p -halophenyl end-group

(2017) Mateusz Janeta et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Photosensitizer (PS)/polyhedral oligomeric silsesquioxane (POSS)-crosslinked nanohybrids for enhanced imaging-guided photodynamic cancer therapy

(2017) Ya-Xuan Zhu et al.   Nanoscale

Unimolecular micelles from POSS-based star-shaped block copolymers for photodynamic therapy

(2017) Pengcheng Zhang et al.   POLYMER

Polyhedral oligomeric silsesquioxane meets “click” chemistry: Rational design and facile preparation of functional hybrid materials

(2017) Yiwen Li et al.   POLYMER

First step towards a model system of the drug delivery network based on amide-POSS nanocarriers

(2017) Łukasz John et al.   RSC Advances

Dual Stimuli-Responsive Hybrid Polymeric Nanoparticles Self-Assembled from POSS-Based Starlike Copolymer-Drug Conjugates for Efficient Intracellular Delivery of Hydrophobic Drugs

(2016) Qingqing Yang et al.   ACS Applied Materials & Interfaces

Nanoscale Biodegradable Organic-Inorganic Hybrids for Efficient Cell Penetration and Drug Delivery

(2016) Sebastian Hörner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inorganic Nanoparticles for Image-Guided Therapy

(2016) Hong Yeol Yoon et al.   BIOCONJUGATE CHEMISTRY

Synthesis and Antibacterial Study of Sulfobetaine/Quaternary Ammonium-Modified Star-Shaped Poly[2-(dimethylamino)ethyl methacrylate]-Based Copolymers with an Inorganic Core

(2016) Yuji Pu et al.   BIOMACROMOLECULES

Rapid Preparation of Silsesquioxane-Based Ionic Liquids

(2016) Liguo Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cubic Polyhedral Oligomeric Silsesquioxane Based Functional Materials: Synthesis, Assembly, and Applications

(2016) Qun Ye et al.   Chemistry-An Asian Journal

Synthesis and assembly of polyhedral oligomeric silsesquioxane end-capped amphiphilic polymer to enhance the fluorescent intensity of tetraphenylethene

(2016) Jin Wu et al.   COLLOID AND POLYMER SCIENCE

Enhanced cellular uptake of protoporphyrine IX/linolenic acid-conjugated spherical nanohybrids for photodynamic therapy

(2016) Hye-In Lee et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

A simple approach to a new T8-POSS based MRI contrast agent

(2016) Helene Strauch et al.   DALTON TRANSACTIONS

An efficient synthetic route for a soluble silsesquioxane-daunorubicin conjugate

(2016) K. Rozga-Wijas et al.   EUROPEAN POLYMER JOURNAL

Mucin-1-Antibody-Conjugated Mesoporous Silica Nanoparticles for Selective Breast Cancer Detection in a Mucin-1 Transgenic Murine Mouse Model

(2016) Didier Dréau et al.   Journal of Biomedical Nanotechnology

Fluorinated POSS-Star Polymers for19F MRI

(2016) Kewei Wang et al.   MACROMOLECULAR CHEMISTRY AND PHYSICS

Organosilica hybrid nanomaterials with a high organic content: syntheses and applications of silsesquioxanes

(2016) Jonas G. Croissant et al.   Nanoscale

Synthesis and metal complexation of dual-functionalized silsesquioxane nanoparticles by sequential thiol–epoxy click and esterification reactions

(2016) Shun Shibasaki et al.   REACTIVE & FUNCTIONAL POLYMERS

Hybrid Nanomaterials Based on Iron Oxide Nanoparticles and Mesoporous Silica Nanoparticles: Overcoming Challenges in Current Cancer Treatments

(2016) Merlis P. Alvarez-Berríos et al.   Journal of Chemistry

Polyhedral Oligomeric Silsesquioxane Functionalized Carbon Dots for Cell Imaging

(2015) Wen-Jing Wang et al.   ACS Applied Materials & Interfaces

Azobenzene-Functionalized Cage Silsesquioxanes as Inorganic-Organic Hybrid, Photoresponsive, Nanoscale, Building Blocks

(2015) Yun Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Redox-Responsive Porphyrin-Based Polysilsesquioxane Nanoparticles for Photodynamic Therapy of Cancer Cells

(2015) Daniel Vega et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Polysilsesquioxane nanoparticles for triggered release of cisplatin and effective cancer chemoradiotherapy

(2015) Joseph Della Rocca et al.   Nanomedicine-Nanotechnology Biology and Medicine

New nanoplatforms based on UCNPs linking with polyhedral oligomeric silsesquioxane (POSS) for multimodal bioimaging

(2015) Xiaoqian Ge et al.   Nanoscale

Upconversion Nanoparticles: From Hydrophobic to Hydrophilic Surfaces

(2014) Verena Muhr et al.   ACCOUNTS OF CHEMICAL RESEARCH

Water soluble octa-functionalized POSS: all-click chemistry synthesis and efficient host–guest encapsulation

(2014) Jin Han et al.   CHEMICAL COMMUNICATIONS

Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics

(2014) Guanying Chen et al.   CHEMICAL REVIEWS

Cinnamate-Functionalized Cage Silsesquioxanes as Photoreactive Nanobuilding Blocks

(2014) Wenyan Yang et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Synthesis and self-assembly of stimuli-responsive amphiphilic block copolymers based on polyhedral oligomeric silsesquioxane

(2014) Lizhi Hong et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Facile fabrication of OA-POSS modified near-infrared-emitting CdSeTe alloyed quantum dots and their bioapplications

(2014) Xue Zhao et al.   NEW JOURNAL OF CHEMISTRY

Bioreducible POSS-Cored Star-Shaped Polycation for Efficient Gene Delivery

(2013) Yan-Yu Yang et al.   ACS Applied Materials & Interfaces

Synthesis of peptide dendrimers with polyhedral oligomeric silsesquioxane cores via click chemistry

(2013) Yu-Ji Pu et al.   CHINESE CHEMICAL LETTERS

Polyhedral Oligomeric Silsesquioxane-F68 Hybrid Vesicles for Folate Receptor Targeted Anti-Cancer Drug Delivery

(2013) Bindu P. Nair et al.   LANGMUIR

Synthesis of highly luminescent POSS-coated CdTe quantum dots and their application in trace Cu2+ detection

(2013) Xue Zhao et al.   Journal of Materials Chemistry A

Synthesis and Biophysical Study of Disassembling Nanohybrid Bioconjugates with a Cubic Octasilsesquioxane Core

(2012) Beatriz Trastoy et al.   ADVANCED FUNCTIONAL MATERIALS

Silica-based nanoprobes for biomedical imaging and theranostic applications

(2012) Juan L. Vivero-Escoto et al.   CHEMICAL SOCIETY REVIEWS

A novel luminescent bifunctional POSS as a molecular platform for biomedical applications

(2012) Francesco Olivero et al.   DALTON TRANSACTIONS

From pico to nano: biofunctionalization of cube-octameric silsesquioxanes by peptides and miniproteins

(2012) Sebastian Fabritz et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Glycoside and peptide clustering around the octasilsesquioxane scaffold via photoinduced free-radical thiol–ene coupling. The observation of a striking glycoside cluster effect

(2012) Mauro Lo Conte et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cube-octameric silsesquioxane-mediated cargo peptide delivery into living cancer cells

(2012) Sebastian Hörner et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Bioconjugation on cube-octameric silsesquioxanes

(2012) Sebastian Fabritz et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cubic Octasilsesquioxanes, Cyclotetrasiloxanes, and Disiloxanes Maximally Functionalized with Silicon-Bridged Interacting Triferrocenyl Units

(2012) Sonia Bruña et al.   ORGANOMETALLICS

Fluorescent Conjugated Polyelectrolytes for Bioimaging

(2011) Kan-Yi Pu et al.   ADVANCED FUNCTIONAL MATERIALS

Bimodal Quantitative Monitoring for Enzymatic Activity with Simultaneous Signal Increases in19F NMR and Fluorescence Using Silica Nanoparticle-Based Molecular Probes

(2011) Kazuo Tanaka et al.   BIOCONJUGATE CHEMISTRY

Synthesis and Evaluation of Nanoglobular Macrocyclic Mn(II) Chelate Conjugates as Non-Gadolinium(III) MRI Contrast Agents

(2011) Mingqian Tan et al.   BIOCONJUGATE CHEMISTRY

Heavy metal-free 19F NMR probes for quantitative measurements of glutathione reductase activity using silica nanoparticles as a signal quencher

(2011) Kazuo Tanaka et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Upconversion nanophosphors for small-animal imaging

(2011) Jing Zhou et al.   CHEMICAL SOCIETY REVIEWS

Inorganic-Organic Hybrid Nanomaterials for Therapeutic and Diagnostic Imaging Applications

(2011) Juan L. Vivero-Escoto et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hierarchical Self-Assembly of Polyhedral Oligomeric Silsesquioxane End-Capped Stimuli-Responsive Polymer: From Single Micelle to Complex Micelle

(2011) Li Ma et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Energy Transfer between Conjugated-Oligoelectrolyte-Substituted POSS and Gold Nanocluster for Multicolor Intracellular Detection of Mercury Ion

(2011) Kan-Yi Pu et al.   Journal of Physical Chemistry C

Peptide-based lipid mimetics with tunable core properties via thiol–alkyne chemistry

(2011) Jacob G. Ray et al.   Polymer Chemistry

Polyhedral Oligomeric Silsesquioxanes-Containing Conjugated Polymer Loaded PLGA Nanoparticles with Trastuzumab (Herceptin) Functionalization for HER2-Positive Cancer Cell Detection

(2010) Kai Li et al.   ADVANCED FUNCTIONAL MATERIALS

Conjugated Oligoelectrolyte Harnessed Polyhedral Oligomeric Silsesquioxane as Light-Up Hybrid Nanodot for Two-Photon Fluorescence Imaging of Cellular Nucleus

(2010) Kan-Yi Pu et al.   ADVANCED MATERIALS

Recent Developments in the Chemistry of Cubic Polyhedral Oligosilsesquioxanes

(2010) David B. Cordes et al.   CHEMICAL REVIEWS

Synthesis of Amphiphilic Polyhedral Oligomeric Silsesquioxane Having a Hydrophobic Fluorescent Dye Group and Its Formation of Fluorescent Nanoparticles in Water

(2010) Shin-ya Kuwahara et al.   CHEMISTRY LETTERS

Octakis(3-azidopropyl)octasilsesquioxane: A Versatile Nanobuilding Block for the Efficient Preparation of Highly Functionalized Cube-Octameric Polyhedral Oligosilsesquioxane Frameworks Through Click Assembly

(2010) Beatriz Trastoy et al.   CHEMISTRY-A EUROPEAN JOURNAL

A “Clickable” Hybrid Nanocluster of Cubic Symmetry

(2010) Dirk Heyl et al.   CHEMISTRY-A EUROPEAN JOURNAL

Macrocyclic Gd3+Chelates Attached to a Silsesquioxane Core as Potential Magnetic Resonance Imaging Contrast Agents: Synthesis, Physicochemical Characterization, and Stability Studies

(2010) Jörg Henig et al.   INORGANIC CHEMISTRY

Nano Building Blocks via Iodination of [PhSiO1.5]n, Forming [p-I-C6H4SiO1.5]n(n= 8, 10, 12), and a New Route to High-Surface-Area, Thermally Stable, Microporous Materials via Thermal Elimination of I2

(2010) M. F. Roll et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Novel Poly(l-glutamic acid) Dendrimer Based Drug Delivery System with Both pH-Sensitive and Targeting Functions

(2010) Hui Yuan et al.   MOLECULAR PHARMACEUTICS

Towards click bioconjugations on cube-octameric silsesquioxane scaffolds

(2010) Sebastian Fabritz et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Mesoporous Silica Nanoparticles for Intracellular Controlled Drug Delivery

(2010) Juan L. Vivero-Escoto et al.   Small

Cationic Oligofluorene-Substituted Polyhedral Oligomeric Silsesquioxane as Light-Harvesting Unimolecular Nanoparticle for Fluorescence Amplification in Cellular Imaging

(2009) Kan-Yi Pu et al.   ADVANCED MATERIALS

Targeted intracellular codelivery of chemotherapeutics and nucleic acid with a well-defined dendrimer-based nanoglobular carrier

(2009) Todd L. Kaneshiro et al.   BIOMATERIALS

Reversible signal regulation system of 19F NMR by redox reactions using a metal complex as a switching module

(2009) Kazuo Tanaka et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and characterization of highly pure azido-functionalized polyhedral oligomeric silsesquioxanes (POSS)

(2009) Vuthichai Ervithayasuporn et al.   CHEMICAL COMMUNICATIONS

Multi-modal 19F NMR probe using perfluorinated cubic silsesquioxane-coated silica nanoparticles for monitoring enzymatic activity

(2008) Kazuo Tanaka et al.   CHEMICAL COMMUNICATIONS