Novel Thiosemicarbazone Derivatives: In Vitro and In Silico Evaluation as Potential MAO-B Inhibitors

Synthesis of new hydrazone derivatives and evaluation of their monoamine oxidase inhibitory activity

(2021) Fatih Tok et al.   BIOORGANIC CHEMISTRY

Novel 2,5-disubstituted-1,3,4-oxadiazole derivatives as MAO-B inhibitors: Synthesis, biological evaluation and molecular modeling studies

(2021) Fatih Tok et al.   BIOORGANIC CHEMISTRY

Reversible Small Molecule Inhibitors of MAO A and MAO B with Anilide Motifs

(2020) Jens Hagenow et al.   Drug Design Development and Therapy

Multifunctional quinoxaline-hydrazone derivatives with acetylcholinesterase and monoamine oxidases inhibitory activities as potential agents against Alzheimer’s disease

(2020) Ulviye Acar Çevik et al.   MEDICINAL CHEMISTRY RESEARCH

Inhibitions of monoamine oxidases and acetylcholinesterase by 1-methyl, 5-phenyl substituted thiosemicarbazones: Synthesis, biochemical, and computational investigations

(2020) Githa Elizabeth Mathew et al.   PROCESS BIOCHEMISTRY

Solid-state photochromic properties, mechanism and electrospun membranes of (E)-2-(benzo[ b ]thiophen-2-ylmethylene)-N-ethylhydrazine-1-carbothioamide

(2018) Yuqian Qiao et al.   DYES AND PIGMENTS

Design, synthesis and biological assessment of new thiazolylhydrazine derivatives as selective and reversible h MAO-A inhibitors

(2018) Nafiz Öncü Can et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Tight-Binding Inhibition of Human Monoamine Oxidase B by Chromone Analogs: A Kinetic, Crystallographic, and Biological Analysis

(2018) Joana Reis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Kinetics, mechanism, and inhibition of monoamine oxidase

(2018) Rona R. Ramsay et al.   JOURNAL OF NEURAL TRANSMISSION

In vitro and in silico evaluation of new thiazole compounds as monoamine oxidase inhibitors

(2018) Begüm Nurpelin Sağlık et al.   BIOORGANIC CHEMISTRY

MAO enzymes inhibitory activity of new benzimidazole derivatives including hydrazone and propargyl side chains

(2017) Özgür Devrim Can et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, and pharmacological evaluation of 2-amino-5-nitrothiazole derived semicarbazones as dual inhibitors of monoamine oxidase and cholinesterase: effect of the size of aryl binding site

(2017) Rati K. P. Tripathi et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis of New Hydrazone Derivatives for MAO Enzymes Inhibitory Activity

(2017) Nafiz Öncü Can et al.   MOLECULES

Design and Synthesis of New Benzothiazole Compounds as Selective hMAO-B Inhibitors

(2017) Sinem Ilgın et al.   MOLECULES

Design, synthesis, and AChE inhibitory activity of new benzothiazole–piperazines

(2016) Ümide Demir Özkay et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Exploration of a Library of 3,4-(Methylenedioxy)aniline-Derived Semicarbazones as Dual Inhibitors of Monoamine Oxidase and Acetylcholinesterase: Design, Synthesis, and Evaluation

(2016) Rati K. P. Tripathi et al.   ChemMedChem

Synthesis of new donepezil analogues and investigation of their effects on cholinesterase enzymes

(2016) Begüm Nurpelin Sağlık et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Spectroscopic and TD-DFT studies on the turn-off fluorescent chemosensor based on anthraldehyde N(4) cyclohexyl thiosemicarbazone for the selective recognition of fluoride and copper ions

(2016) Sabeel M. Basheer et al.   POLYHEDRON

Inhibitors of MAO-A and MAO-B in Psychiatry and Neurology

(2016) John P. M. Finberg et al.   Frontiers in Pharmacology

Erratum: Corrigendum: Combating neurodegenerative disease with chemical probes and model systems

(2015) Priyanka Narayan et al.   Nature Chemical Biology

Thiosemicarbazide, a fragment with promising indolamine-2,3-dioxygenase (IDO) inhibition properties

(2014) Silvia Serra et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, in vitro MAO-B Inhibitory Evaluation, and Computational Studies of Some 6-Nitrobenzothiazole-Derived Semicarbazones

(2013) Rati K. P. Tripathi et al.   ChemMedChem

Distribution of Monoamine Oxidase Proteins in Human Brain: Implications for Brain Imaging Studies

(2013) Junchao Tong et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Target- and Mechanism-Based Therapeutics for Neurodegenerative Diseases: Strength in Numbers

(2013) Paul C. Trippier et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Role of Monoamine Oxidase Inhibitors in Depression Treatment Guidelines

(2012) Michael E. Thase   JOURNAL OF CLINICAL PSYCHIATRY

A Series of α-Heterocyclic Carboxaldehyde Thiosemicarbazones Inhibit Topoisomerase IIα Catalytic Activity

(2010) He Huang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, structure–activity relationships and molecular modeling studies of new indole inhibitors of monoamine oxidases A and B

(2008) Giuseppe La Regina et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structure of human monoamine oxidase A at 2.2-A resolution: The control of opening the entry for substrates/inhibitors

(2008) S.-Y. Son et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA