Multifunctional Eco-Friendly Synthesis of ZnO Nanoparticles in Biomedical Applications

This work describes an environmental-friendly preparation of ZnO nanoparticles using aqueous oat extract. The advanced electrochemical and optical features of green synthesized ZnONPs displayed excellent antibacterial activity and exhibited an important role in pharmaceutical determinations. The formation of nanoscale ZnO was confirmed using various spectroscopic and microscopic investigations. The formed nanoparticles were found to be around 100 nm. The as-prepared ZnONPs were monitored for their antibacterial potential against different bacterial strains. The inhibition zones for ZnONPs were found as Escherichia coli (16 mm), Pseudomonas aeruginosa (17 mm), Staphylococcus aureus (12 mm) and Bacillus subtilis (11 mm) using a 30-mu g mL(-1) sample concentration. In addition, ZnONPs exhibited significant antioxidant effects, from 58 to 67%, with an average IC50 value of 0.88 +/- 0.03 scavenging activity and from 53 to 71% (IC50 value of 0.73 +/- 0.05) versus the scavenging free radicals DPPH and ABTS, respectively. The photocatalytic potential of ZnONPs for Rhodamine B dye degradation under UV irradiation was calculated. The photodegradation process was carried out as a function of time-dependent and complete degradation (nearly 98%), with color removal after 120 min. Conclusively, the synthesized ZnONPs using oat biomass might provide a great promise in the future for biomedical applications.

Automated summary

This work describes the environmentally friendly synthesis of zinc oxide nanoparticles using aqueous oat extract. The synthesized nanoparticles exhibited excellent antibacterial and antioxidant activity, making them promising for biomedical applications. Spectroscopic and microscopic investigations confirmed the formation of nanoscale zinc oxide particles with an average size of 100 nm. The nanoparticles showed significant inhibitory effects against various bacterial strains and demonstrated strong antioxidant activity. Additionally, zinc oxide nanoparticles exhibited efficient photocatalytic degradation of Rhodamine B dye under UV irradiation.