Magnolol and Honokiol Inhibited the Function and Expression of BCRP with Mechanism Exploration

Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer

(2021) Chao Dong et al.   Frontiers in Pharmacology

Natural Lignans Honokiol and Magnolol as Potential Anticarcinogenic and Anticancer Agents. A Comprehensive Mechanistic Review

(2021) Sayeh Mottaghi et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Magnolol alleviates Alzheimer's disease-like pathology in transgenic C. elegans by promoting microglia phagocytosis and the degradation of beta-amyloid through activation of PPAR-γ

(2020) Zhishen Xie et al.   BIOMEDICINE & PHARMACOTHERAPY

The Impact of Breast Cancer Resistance Protein (BCRP/ABCG2) on Drug Transport Across Caco-2 Cell Monolayers

(2020) Iichiro Kawahara et al.   DRUG METABOLISM AND DISPOSITION

Can NF-κB Be Considered a Valid Drug Target in Neoplastic Diseases? Our Point of View

(2020) Manuela Labbozzetta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Overcoming Multidrug Resistance: Flavonoid and Terpenoid Nitrogen-Containing Derivatives as ABC Transporter Modulators

(2020) Bruno M. F. Gonçalves et al.   MOLECULES

Phytochemicals: Potential Lead Molecules for MDR Reversal

(2020) Boshra Tinoush et al.   Frontiers in Pharmacology

PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers

(2020) Rui Liu et al.   Cell Death & Disease

My journey from tyrosine phosphorylation inhibitors to targeted immune therapy as strategies to combat cancer

(2019) Alexander Levitzki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural products as multidrug resistance modulators in cancer

(2019) Amit Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Honokiol: A Review of Its Anticancer Potential and Mechanisms

(2019) Chon Phin Ong et al.   Cancers

Safety and Toxicology of Magnolol and Honokiol

(2018) Andrea Sarrica et al.   PLANTA MEDICA

Honokiol Inhibits Proliferation, Invasion and Induces Apoptosis Through Targeting Lyn Kinase in Human Lung Adenocarcinoma Cells

(2018) Xi Dai et al.   Frontiers in Pharmacology

Alpinumisoflavone attenuates lipopolysaccharide-induced acute lung injury by regulating the effects of anti-oxidation and anti-inflammation both in vitro and in vivo

(2018) Pei-Ying Li et al.   RSC Advances

Magnolol attenuates the inflammation and enhances phagocytosis through the activation of MAPK, NF-κB signal pathways in vitro and in vivo

(2018) Hongce Chen et al.   MOLECULAR IMMUNOLOGY

Magnolol ameliorates pneumonectomy and monocrotaline-induced pulmonary arterial hypertension in rats through inhibition of angiotensin II and endothelin-1 expression

(2018) Hung Chang et al.   PHYTOMEDICINE

Chain-breaking antioxidant activity of hydroxylated and methoxylated magnolol derivatives: the role of H-bonds

(2017) Andrea Baschieri et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Magnolol protects channel catfish from Aeromonas hydrophila infection via inhibiting the expression of aerolysin

(2017) Jing Dong et al.   VETERINARY MICROBIOLOGY

Increased Systemic Exposure of Methotrexate by a Polyphenol-Rich Herb via Modulation on Efflux Transporters Multidrug Resistance–Associated Protein 2 and Breast Cancer Resistance Protein

(2016) Chung-Ping Yu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Effects of natural nuclear factor-kappa B inhibitors on anticancer drug efflux transporter human P-glycoprotein

(2015) Tomohiro Nabekura et al.   BIOMEDICINE & PHARMACOTHERAPY

Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in Drug Transport—an Update

(2014) Qingcheng Mao et al.   AAPS Journal

Intravenous administration of Honokiol provides neuroprotection and improves functional recovery after traumatic brain injury through cell cycle inhibition

(2014) Haiquan Wang et al.   NEUROPHARMACOLOGY

Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells

(2013) Meng-Chuan Chen et al.   BIOCHEMICAL PHARMACOLOGY

Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics

(2013) Akintunde Akinleye et al.   Journal of Hematology & Oncology

Tyrosine Kinase Inhibitors Influence ABCG2 Expression in EGFR-Positive MDCK BCRP Cells via the PI3K/Akt Signaling Pathway

(2012) Anne Pick et al.   ChemMedChem

A Novel Naturally Occurring Salicylic Acid Analogue Acts as an Anti-Inflammatory Agent by Inhibiting Nuclear Factor-kappaB Activity in RAW264.7 Macrophages

(2012) Tiantai Zhang et al.   MOLECULAR PHARMACEUTICS

Elevated BCRP/ABCG2 Expression Confers Acquired Resistance to Gefitinib in Wild-Type EGFR-Expressing Cells

(2011) Yun-Ju Chen et al.   PLoS One

Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression

(2011) Takeo Nakanishi et al.   Chinese Journal of Cancer

Honokiol and Magnolol as Multifunctional Antioxidative Molecules for Dermatologic Disorders

(2010) Jui-Lung Shen et al.   MOLECULES

Reversal of ABC Drug Transporter-Mediated Multidrug Resistance in Cancer Cells: Evaluation of Current Strategies

(2010) Chung-Pu Wu et al.   Current Molecular Pharmacology

Honokiol, a Multifunctional Antiangiogenic and Antitumor Agent

(2009) Levi E. Fried et al.   ANTIOXIDANTS & REDOX SIGNALING

Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells

(2009) Dae-Hee Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY