4.3 Review

A Short Review on the Synthesis of 1,2,4-Triazine Derivatives as Bioactive Compounds

Journal

MINI-REVIEWS IN ORGANIC CHEMISTRY
Volume 18, Issue 8, Pages 1127-1133

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1570193X18666210122154419

Keywords

1; 2; 4-Triazine; fused triazine; heterocycles; biological activity; synthesis; oxo derivatives

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This review discusses the different synthesis methods of triazine/one derivatives and their various effects in pharmaceuticals.
which have attracted great attention in organic synthesis and medicinal chemistry as they have been associated with a broad range of pharmacological activities. 1,2,4-Triazines and their oxo derivatives exhibit a broad range of biological activities, including antimicrobial, antifungal, anticancer, antiinflammatory, besides having importance in the dyes and pesticides field. This review presents the different methods of the synthesis of triazine/one derivatives. Also, this literature surveys the different effects of these compounds in pharmaceuticals.

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