Development of bifunctional biosensors for sensing and dynamic control of glycolysis flux in metabolic engineering

Fine tuning the glycolytic flux ratio of EP-bifido pathway for mevalonate production by enhancing glucose-6-phosphate dehydrogenase (Zwf) and CRISPRi suppressing 6-phosphofructose kinase (PfkA) in Escherichia coli

(2021) Ying Li et al.   Microbial Cell Factories

In vivo evolutionary engineering of riboswitch with high-threshold for N-acetylneuraminic acid production

(2020) Qingxiao Pang et al.   METABOLIC ENGINEERING

Tuning the Binding Affinity of Heme-Responsive Biosensor for Precise and Dynamic Pathway Regulation

(2020) Jian Zhang et al.   iScience

Pyruvate-responsive genetic circuits for dynamic control of central metabolism

(2020) Xianhao Xu et al.   Nature Chemical Biology

Development of an autonomous and bifunctional quorum-sensing circuit for metabolic flux control in engineeredEscherichia coli

(2019) Christina V. Dinh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic-flux dependent regulation of microbial physiology

(2018) Athanasios Litsios et al.   CURRENT OPINION IN MICROBIOLOGY

Toward engineeringE. coliwith an autoregulatory system for lignin valorization

(2018) Weihua Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CRISPRi allows optimal temporal control of N-acetylglucosamine bioproduction by a dynamic coordination of glucose and xylose metabolism in Bacillus subtilis

(2018) Yaokang Wu et al.   METABOLIC ENGINEERING

Regulation of glycolytic flux and overflow metabolism depending on the source of energy generation for energy demand

(2018) Kazuyuki Shimizu et al.   BIOTECHNOLOGY ADVANCES

Insulated transcriptional elements enable precise design of genetic circuits

(2017) Yeqing Zong et al.   Nature Communications

Fundamental Design Principles for Transcription-Factor-Based Metabolite Biosensors

(2017) Ahmad A. Mannan et al.   ACS Synthetic Biology

Succinate production positively correlates with the affinity of the global transcription factor Cra for its effector FBP in Escherichia coli

(2016) Li-Na Wei et al.   Biotechnology for Biofuels

Tailor-made transcriptional biosensors for optimizing microbial cell factories

(2016) Brecht De Paepe et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Analysis of amino acid substitutions in AraC variants that respond to triacetic acid lactone

(2016) Christopher S. Frei et al.   PROTEIN SCIENCE

Dynamic metabolic engineering: New strategies for developing responsive cell factories

(2015) Irene M. Brockman et al.   Biotechnology Journal

Sensitive cells: enabling tools for static and dynamic control of microbial metabolic pathways

(2015) Brady F Cress et al.   CURRENT OPINION IN BIOTECHNOLOGY

Dynamic metabolic engineering: New strategies for developing responsive cell factories

(2015) Irene M. Brockman et al.   Biotechnology Journal

Improving fatty acids production by engineering dynamic pathway regulation and metabolic control

(2014) P. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Scalable production of mechanically tunable block polymers from sugar

(2014) M. Xiong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functioning of a metabolic flux sensor in Escherichia coli

(2013) K. Kochanowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic biology and the development of tools for metabolic engineering

(2012) Jay D. Keasling   METABOLIC ENGINEERING

Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids

(2012) Fuzhong Zhang et al.   NATURE BIOTECHNOLOGY

Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0

(2011) Jan Schellenberger et al.   Nature Protocols

Engineering Static and Dynamic Control of Synthetic Pathways

(2010) William J. Holtz et al.   CELL

Intracellular characterization of aerobic glucose metabolism in seven yeast species by 13C flux analysis and metabolomics

(2010) Stefan Christen et al.   FEMS YEAST RESEARCH

Novel Members of the Cra Regulon Involved in Carbon Metabolism in Escherichia coli

(2010) T. Shimada et al.   JOURNAL OF BACTERIOLOGY

Effect of cra gene knockout together with edd and iclR genes knockout on the metabolism in Escherichia coli

(2008) Dayanidhi Sarkar et al.   ARCHIVES OF MICROBIOLOGY