Rationally Driven Drug Nonradiative Decay via a Label‐Free Polyprodrug Strategy to Renew Tumor Cascade Photothermal‐Chemotherapy

Polyprodrug with Glutathione Depletion and Cascade Drug Activation for Multi-drug Resistance Reversal

(2021) Xuan Xiao et al.   BIOMATERIALS

Synergetic delivery of triptolide and Ce6 with light-activatable liposomes for efficient hepatocellular carcinoma therapy

(2021) Ling Yu et al.   Acta Pharmaceutica Sinica B

Native Mitochondria-Targeting Polymeric Nanoparticles for Mild Photothermal Therapy Rationally Potentiated with Immune Checkpoints Blockade to Inhibit Tumor Recurrence and Metastasis

(2021) Yongbo Zhang et al.   CHEMICAL ENGINEERING JOURNAL

Polyprodrug Nanomedicines: An Emerging Paradigm for Cancer Therapy

(2021) Kuikun Yang et al.   ADVANCED MATERIALS

A Facile Strategy of Boosting Photothermal Conversion Efficiency through State Transformation for Cancer Therapy

(2021) Jie Li et al.   ADVANCED MATERIALS

Vinyl Polymer-based technologies towards the efficient delivery of chemotherapeutic drugs

(2021) Patrícia Pereira et al.   PROGRESS IN POLYMER SCIENCE

Delivery of triptolide with reduction-sensitive polymer nanoparticles for liver cancer therapy on patient-derived xenografts models

(2020) Mengxue He et al.   CHINESE CHEMICAL LETTERS

In situ supramolecular polymerization-enhanced self-assembly of polymer vesicles for highly efficient photothermal therapy

(2020) Yannan Liu et al.   Nature Communications

Illuminating Platinum Transportation while Maximizing Therapeutic Efficacy by Gold Nanoclusters via Simultaneous Near-Infrared-I/II Imaging and Glutathione Scavenging

(2020) Yuanyuan Yang et al.   ACS Nano

Self-Amplification of Tumor Oxidative Stress with Degradable Metallic Complexes for Synergistic Cascade Tumor Therapy

(2020) Gui Chen et al.   NANO LETTERS

Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis

(2020) Nikolay Popgeorgiev et al.   Science Advances

Light-activatable liposomes for repetitive on-demand drug release and immunopotentiation in hypoxic tumor therapy

(2020) Yuanyuan Yang et al.   BIOMATERIALS

Cocktail polyprodrug nanoparticles concurrently release cisplatin and peroxynitrite-generating nitric oxide in cisplatin-resistant cancers

(2020) Chengyan Chu et al.   CHEMICAL ENGINEERING JOURNAL

Intratumorally Injected Photothermal Agent-Loaded Photodynamic Nanocarriers for Ablation of Orthotopic Melanoma and Breast Cancer

(2019) Xiaodong Sun et al.   ACS Biomaterials-Science & Engineering

Boosting Non-Radiative Decay to Do Useful Work: Development of a Multi-Modality Theranostic System from an AIEgen

(2019) Dong Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Small-Molecule Porphyrin-Based Organic Nanoparticles with Remarkable Photothermal Conversion Efficiency for in Vivo Photoacoustic Imaging and Photothermal Therapy

(2019) Fengshou Wu et al.   ACS Applied Materials & Interfaces

NIR-Activated Polymeric Nanoplatform with Upper Critical Solution Temperature for Image-Guided Synergistic Photothermal Therapy and Chemotherapy

(2019) Jia Tian et al.   BIOMACROMOLECULES

A Simple Glutathione-Responsive Turn-On Theranostic Nanoparticle for Dual-Modal Imaging and Chemo-Photothermal Combination Therapy

(2019) Yihui Li et al.   NANO LETTERS

Enzyme-activatable polymer–drug conjugate augments tumour penetration and treatment efficacy

(2019) Quan Zhou et al.   Nature Nanotechnology

Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapy

(2019) Wenjia Zhang et al.   Nature Communications

Biomodal Tumor‐Targeted and Redox‐Responsive Bi 2 Se 3 Hollow Nanocubes for MSOT/CT Imaging Guided Synergistic Low‐Temperature Photothermal Radiotherapy

(2019) Yilin Song et al.   Advanced Healthcare Materials

Smart Unimolecular Micelle-Based Polyprodrug with Dual-Redox Stimuli Response for Tumor Microenvironment: Enhanced in Vivo Delivery Efficiency and Tumor Penetration

(2019) Shuang Bai et al.   ACS Applied Materials & Interfaces

Functionalized theranostic nanocarriers with bio-inspired polydopamine for tumor imaging and chemo-photothermal therapy

(2019) Mehdi Farokhi et al.   JOURNAL OF CONTROLLED RELEASE

Supramolecular Photothermal Effects: A Promising Mechanism for Efficient Thermal Conversion

(2019) Luyang Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Disulfide‐Based Self‐Immolative Linkers and Functional Bioconjugates for Biological Applications

(2019) Zhengyu Deng et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Janus macromolecular brushes for synergistic cascade-amplified photodynamic therapy and enhanced chemotherapy

(2019) Jia Tian et al.   Acta Biomaterialia

Enzyme-induced in vivo assembly of gold nanoparticles for imaging-guided synergistic chemo-photothermal therapy of tumor

(2019) Kuikun Yang et al.   BIOMATERIALS

Second Near-Infrared Conjugated Polymer Nanoparticles for Photoacoustic Imaging and Photothermal Therapy

(2018) Tingting Sun et al.   ACS Applied Materials & Interfaces

Self-Quenched Metal–Organic Particles as Dual-Mode Therapeutic Agents for Photoacoustic Imaging-Guided Second Near-Infrared Window Photochemotherapy

(2018) Da Zhang et al.   ACS Applied Materials & Interfaces

Highly Augmented Drug Loading and Stability of Micellar Nanocomplexes Composed of Doxorubicin and Poly(ethylene glycol)-Green Tea Catechin Conjugate for Cancer Therapy

(2018) Kun Liang et al.   ADVANCED MATERIALS

Near-Infrared-Light-Activatable Nanomaterial-Mediated Phototheranostic Nanomedicines: An Emerging Paradigm for Cancer Treatment

(2018) Raviraj Vankayala et al.   ADVANCED MATERIALS

Concurrent Drug Unplugging and Permeabilization of Polyprodrug-Gated Crosslinked Vesicles for Cancer Combination Chemotherapy

(2018) Xianglong Hu et al.   ADVANCED MATERIALS

Platinum(IV) complex-based two-in-one polyprodrug for a combinatorial chemo-photodynamic therapy

(2018) Dongbo Guo et al.   BIOMATERIALS

Reduction-sensitive fluorescence enhanced polymeric prodrug nanoparticles for combinational photothermal-chemotherapy

(2018) Yuanyuan Zhang et al.   BIOMATERIALS

Anti-inflammatory polymersomes of redox-responsive polyprodrug amphiphiles with inflammation-triggered indomethacin release characteristics

(2018) Jiajia Tan et al.   BIOMATERIALS

A glutathione-responsive sulfur dioxide polymer prodrug as a nanocarrier for combating drug-resistance in cancer chemotherapy

(2018) Wei Shen et al.   BIOMATERIALS

Drug Self-Delivery Systems Based on Hyperbranched Polyprodrugs towards Tumor Therapy

(2018) Xiao Duan et al.   Chemistry-An Asian Journal

Addressing Drug Resistance in Cancer with Macromolecular Chemotherapeutic Agents

(2018) Nathaniel H. Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer

(2018) Jutaek Nam et al.   Nature Communications

Light-driven transformable optical agent with adaptive functions for boosting cancer surgery outcomes

(2018) Ji Qi et al.   Nature Communications

Dual Chemodrug-Loaded Single-Walled Carbon Nanohorns for Multimodal Imaging-Guided Chemo-Photothermal Therapy of Tumors and Lung Metastases

(2018) Jingxing Yang et al.   Theranostics

Self-Stabilized Hyaluronate Nanogel for Intracellular Codelivery of Doxorubicin and Cisplatin to Osteosarcoma

(2018) Yi Zhang et al.   Advanced Science

Supramolecular Nanosystem Based on Pillararene-Capped CuS Nanoparticles for Targeted Chemo-Photothermal Therapy

(2018) Qing-Lan Li et al.   ACS Applied Materials & Interfaces

ROS-sensitive thioketal-linked polyphosphoester-doxorubicin conjugate for precise phototriggered locoregional chemotherapy

(2018) Pei Pei et al.   BIOMATERIALS

A Two-Dimensional Biodegradable Niobium Carbide (MXene) for Photothermal Tumor Eradication in NIR-I and NIR-II Biowindows

(2017) Han Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biological Photothermal Nanodots Based on Self-Assembly of Peptide–Porphyrin Conjugates for Antitumor Therapy

(2017) Qianli Zou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tumor Acidity/NIR Controlled Interaction of Transformable Nanoparticle with Biological Systems for Cancer Therapy

(2017) Dongdong Li et al.   NANO LETTERS

Encapsulation of Au/Fe3O4 nanoparticles into a polymer nanoarchitecture with combined near infrared-triggered chemo-photothermal therapy based on intracellular secondary protein understanding

(2017) Ching-Wen Chen et al.   Journal of Materials Chemistry B

Near-Infrared (NIR)-Absorbing Conjugated Polymer Dots as Highly Effective Photothermal Materials for In Vivo Cancer Therapy

(2016) Shengliang Li et al.   CHEMISTRY OF MATERIALS

Fluorescence properties of several chemotherapy drugs: doxorubicin, paclitaxel and bleomycin

(2016) Najme Sadat Hosseini Motlagh et al.   Biomedical Optics Express

Diketopyrrolopyrrole-Based Semiconducting Polymer Nanoparticles for In Vivo Photoacoustic Imaging

(2015) Kanyi Pu et al.   ADVANCED MATERIALS

When Molecular Probes Meet Self-Assembly: An Enhanced Quenching Effect

(2015) Chunhua Ren et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Interactions in Organic Nanoparticles for Phototheranostic Applications

(2015) Kenneth K. Ng et al.   CHEMICAL REVIEWS

Conjugated-Polyelectrolyte-Based Polyprodrug: Targeted and Image-Guided Photodynamic and Chemotherapy with On-Demand Drug Release upon Irradiation with a Single Light Source

(2014) Youyong Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cell-Penetrating Hyperbranched Polyprodrug Amphiphiles for Synergistic Reductive Milieu-Triggered Drug Release and Enhanced Magnetic Resonance Signals

(2014) Xianglong Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-Step Assembly of DOX/ICG Loaded Lipid–Polymer Nanoparticles for Highly Effective Chemo-photothermal Combination Therapy

(2013) Mingbin Zheng et al.   ACS Nano

Photothermally Triggered Cytosolic Drug Delivery via Endosome Disruption Using a Functionalized Reduced Graphene Oxide

(2013) Hyunwoo Kim et al.   ACS Nano

Polyprodrug Amphiphiles: Hierarchical Assemblies for Shape-Regulated Cellular Internalization, Trafficking, and Drug Delivery

(2013) Xianglong Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photo-Triggered Release of Caged Camptothecin Prodrugs from Dually Responsive Shell Cross-Linked Micelles

(2013) Xianglong Hu et al.   MACROMOLECULES

Glutathione-responsive nano-vehicles as a promising platform for targeted intracellular drug and gene delivery

(2011) Ru Cheng et al.   JOURNAL OF CONTROLLED RELEASE

Cell-Specific, Activatable, and Theranostic Prodrug for Dual-Targeted Cancer Imaging and Therapy

(2011) Santimukul Santra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Co-delivery of Doxorubicin and Bcl-2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug-Resistant Cancer Cells

(2009) Alex M. Chen et al.   Small