Periprocedural management of abnormal coagulation parameters and thrombocytopenia in patients with cirrhosis: Guidance from the SSC of the ISTH

The efficacy and safety of thrombopoietin receptor agonists in patients with chronic liver disease undergoing elective procedures: a systematic review and meta-analysis

(2021) Ingrid Lindquist et al.   PLATELETS

Transfusion with Cryoprecipitate for Very Low Fibrinogen Levels Does Not Affect Bleeding or Survival in Critically Ill Cirrhosis Patients

(2021) Isadore Budnick et al.   THROMBOSIS AND HAEMOSTASIS

Fresh Frozen Plasma Transfusion in Acute Variceal Hemorrhage: Results from a Multicenter Cohort Study

(2021) Arpan Mohanty et al.   LIVER INTERNATIONAL

Pre-procedural use of thrombopoietin-receptor agonists in cirrhosis and severe thrombocytopenia: A systematic review and meta-analysis

(2021) Peter D. Rose et al.   DIGESTIVE AND LIVER DISEASE

AGA Clinical Practice Guideline on the Management of Coagulation Disorders in Patients With Cirrhosis

(2021) Robert S. O’Shea et al.   GASTROENTEROLOGY

ACG Clinical Guideline

(2020) Douglas A. Simonetto et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Thrombocytopenia in Chronic Liver Disease

(2020) Kathy M. Nilles et al.   Clinics in Liver Disease

Acute kidney injury in decompensated cirrhosis is associated with both hypo‐ and hyper‐coagulable features

(2020) Alberto Zanetto et al.   HEPATOLOGY

Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial

(2020) Ian Roberts et al.   LANCET

Incidence of Bleeding and Thrombosis in Patients with Liver Disease

(2020) Lara N. Roberts et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Global hemostatic status in patients with acute‐on‐chronic liver failure and septics without underlying liver disease

(2020) Ton Lisman et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Thrombopoietin Receptor Agonists in Patients with Chronic Liver Disease

(2020) Saro Khemichian et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Major Thromboembolic Complications in Liver Transplantation

(2020) Christine Nguyen-Buckley et al.   TRANSPLANTATION

Prophylactic fresh frozen plasma and platelet transfusion have a prothrombotic effect in patients with liver disease

(2020) Fien A. Meijenfeldt et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Coagulation in Cirrhosis

(2019) Jacqueline G. O’Leary et al.   GASTROENTEROLOGY

Scientific and Standardization Committee Communication: Guidance document on the periprocedural management of patients on chronic oral anticoagulant therapy: recommendations for standardized reporting of procedural/surgical bleed risk and patient‐specific thromboembolic risk

(2019) Alex C Spyropoulos et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Safety of coagulation factor concentrates guided by ROTEM™-analyses in liver transplantation: results from 372 procedures

(2019) Matthias Hartmann et al.   BMC Anesthesiology

Fresh frozen plasma transfusion in patients with cirrhosis and coagulopathy: effect on conventional coagulation tests and thrombomodulin-modified thrombin generation

(2019) Amanda Bruder Rassi et al.   JOURNAL OF HEPATOLOGY

Society of Interventional Radiology Consensus Guidelines for the Periprocedural Management of Thrombotic and Bleeding Risk in Patients Undergoing Percutaneous Image-Guided Interventions—Part II: Recommendations

(2019) Indravadan J. Patel et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

A Randomized Control Trial of Thromboelastography-Guided Transfusion in Cirrhosis for High-Risk Invasive Liver-Related Procedures

(2019) Sudheer K Vuyyuru et al.   DIGESTIVE DISEASES AND SCIENCES

British Society of Haematology Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding

(2018) Laura Green et al.   BRITISH JOURNAL OF HAEMATOLOGY

Thrombopoietin receptor agonists and risk of portal vein thrombosis in patients with liver disease and thrombocytopenia: A meta-analysis

(2018) Lorenzo Loffredo et al.   DIGESTIVE AND LIVER DISEASE

Balanced haemostasis with both hypo- and hyper-coagulable features in critically ill patients with acute-on-chronic-liver failure

(2018) Caleb Fisher et al.   JOURNAL OF CRITICAL CARE

Low molecular weight heparin does not increase bleeding and mortality post-endoscopic variceal band ligation in cirrhotic patients

(2018) Marcello Bianchini et al.   LIVER INTERNATIONAL

Acute kidney injury, but not sepsis, is associated with higher procedure-related bleeding in patients with decompensated cirrhosis

(2018) Adelina Hung et al.   LIVER INTERNATIONAL

Low Fibrinogen Levels Are Associated with Bleeding After Varices Ligation in Thrombocytopenic Cirrhotic Patients

(2018) Edoardo G. Giannini et al.   Annals of Hepatology

Bleeding after invasive procedures is rare and unpredicted by platelet counts in cirrhotic patients with thrombocytopenia

(2017) Grazia Napolitano et al.   European Journal of Internal Medicine

Fibrinogen as an independent predictor of mortality in decompensated cirrhosis and bleeding

(2017) Michael J. R. Desborough et al.   HEPATOLOGY

Oral Surgical Treatment of Patients With Chronic Liver Disease: Assessments of Bleeding and Its Relationship With Thrombocytopenia and Blood Coagulation Parameters

(2017) Nadia Cocero et al.   JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial

(2017) Haleema Shakur et al.   LANCET

Coagulation parameters and major bleeding in critically ill patients with cirrhosis

(2016) Andreas Drolz et al.   HEPATOLOGY

Procoagulant changes in fibrin clot structure in patients with cirrhosis are associated with oxidative modifications of fibrinogen

(2016) G. C. G. Hugenholtz et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Utility of Intravascular US–Guided Portal Vein Access during Transjugular Intrahepatic Portosystemic Shunt Creation: Retrospective Comparison with Conventional Technique in 109 Patients

(2016) Anil K. Pillai et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial

(2016) M Irem Baharoglu et al.   LANCET

Thrombelastography-guided blood product use before invasive procedures in cirrhosis with severe coagulopathy: A randomized, controlled trial

(2015) Lesley De Pietri et al.   HEPATOLOGY

Definition of clinically relevant non-major bleeding in studies of anticoagulants in atrial fibrillation and venous thromboembolic disease in non-surgical patients: communication from the SSC of the ISTH

(2015) S. Kaatz et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Patterns of blood component use in cirrhosis: a nationwide study

(2015) Michael J. R. Desborough et al.   LIVER INTERNATIONAL

Hemorrhagic Complications Following Abdominal Paracentesis in Acute on Chronic Liver Failure

(2015) Su Lin et al.   MEDICINE

Prothrombin Time and Activated Partial Thromboplastin Time Testing: A Comparative Effectiveness Study in a Million-Patient Sample

(2015) Manu N. Capoor et al.   PLoS One

Safety of Ultrasound-Guided Thoracentesis in Patients With Abnormal Preprocedural Coagulation Parameters

(2013) Rebecca M. Hibbert et al.   CHEST

Global hemostasis tests in patients with cirrhosis before and after prophylactic platelet transfusion

(2012) Armando Tripodi et al.   LIVER INTERNATIONAL

Transfusion Rate for 500 Consecutive Liver Transplantations

(2012) Luc Massicotte et al.   TRANSPLANTATION

Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial

(2010)   LANCET

Dose of Prophylactic Platelet Transfusions and Prevention of Hemorrhage

(2010) Sherrill J. Slichter et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Prospective Study of Conventional and Expanded Coagulation Indices in Predicting Ulcer Bleeding After Variceal Band Ligation

(2009) Evandra Cristina Vieira da Rocha et al.   Clinical Gastroenterology and Hepatology

Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients

(2009) S. SCHULMAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Recombinant factor VIIa for variceal bleeding in patients with advanced cirrhosis: A randomized, controlled trial

(2008) Jaime Bosch et al.   HEPATOLOGY

Liver biopsy

(2008) Don C. Rockey et al.   HEPATOLOGY

Thrombocytopenia associated with chronic liver disease

(2008) Nezam Afdhal et al.   JOURNAL OF HEPATOLOGY