Comparative Reductions in Investigator-Reported and Adjudicated Ischemic Events in REDUCE-IT

Reconfiguring the Cardiovascular Clinical Trial Enterprise in the United States

(2021) Deepak L. Bhatt   JAMA Network Open

Effect of Icosapent Ethyl on Progression of Coronary Atherosclerosis in Patients with Elevated Triglycerides on Statin Therapy: A prospective, placebo-controlled randomized trial (EVAPORATE): Interim Results

(2020) Matthew J Budoff et al.   CARDIOVASCULAR RESEARCH

Comparison of Outcome Adjudication by Investigators and by a Central End Point Committee in Heart Failure Trials

(2020) Benoît Tyl et al.   Circulation-Heart Failure

Effect of icosapent ethyl on progression of coronary atherosclerosis in patients with elevated triglycerides on statin therapy: final results of the EVAPORATE trial

(2020) Matthew J Budoff et al.   EUROPEAN HEART JOURNAL

REDUCE-IT INTERIM: Accumulation of Data Across Prespecified Interim Analyses to Final Results

(2020) Brian Olshansky et al.   European Heart Journal-Cardiovascular Pharmacotherapy

Reduction in Revascularization With Icosapent Ethyl

(2020) Benjamin E. Peterson et al.   CIRCULATION

Sotagliflozin in Patients with Diabetes and Chronic Kidney Disease

(2020) Deepak L. Bhatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure

(2020) Deepak L. Bhatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Icosapent Ethyl on Total Ischemic Events: From REDUCE-IT

(2019) Deepak L. Bhatt et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

REDUCE-IT

(2019) Deepak L Bhatt   EUROPEAN HEART JOURNAL

Reduction in First and Total Ischemic Events With Icosapent Ethyl Across Baseline Triglyceride Tertiles

(2019) Deepak L. Bhatt et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

REDUCE-IT USA: Results from the 3,146 Patients Randomized in the United States

(2019) Deepak L. Bhatt et al.   CIRCULATION

2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials

(2018) Karen A. Hicks et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Endpoints in diabetes cardiovascular outcome trials

(2018) Tejas Patel et al.   LANCET

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia

(2018) Deepak L. Bhatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Central adjudication of serious adverse events did not affect trial’s safety results: Data from the Efficacy of Nitric Oxide in Stroke (ENOS) trial

(2018) Peter J. Godolphin et al.   PLoS One

Characterization of cardiovascular clinical events and impact of event adjudication on the treatment effect of darapladib versus placebo in patients with stable coronary heart disease: Insights from the STABILITY trial

(2018) Claes Held et al.   AMERICAN HEART JOURNAL

Investigator-Reported Bleeding Versus Post Hoc Adjudication of Bleeding

(2016) Tannas Jatene et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Architecture design of a generic centralized adjudication module integrated in a web-based clinical trial management system

(2015) Wenle Zhao et al.   Clinical Trials

2014 ACC/AHA Key Data Elements and Definitions for Cardiovascular Endpoint Events in Clinical Trials

(2015) Karen A. Hicks et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Ticagrelor Effects on Myocardial Infarction and the Impact of Event Adjudication in the PLATO (Platelet Inhibition and Patient Outcomes) Trial

(2014) Kenneth W. Mahaffey et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

ACCF/AHA 2011 Key Data Elements and Definitions of a Base Cardiovascular Vocabulary for Electronic Health Records

(2011) William S. Weintraub et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Determination of hospitalization type by investigator case report form or adjudication committee in a large heart failure clinical trial (β-Blocker Evaluation of Survival Trial [BEST])

(2010) Peter Carson et al.   AMERICAN HEART JOURNAL

Do we need to adjudicate major clinical events?

(2008) Christopher B Granger et al.   Clinical Trials