Article
Biochemical Research Methods
Yi-Lun Yan, Dong Guo, Jia-Lin Wu, Xi-Hao Tang, Jia-Jun Luo, Shu-Qing Li, Jun Fan, Sheng-Run Zheng, Wei-Guang Zhang, Song-Liang Cai
Summary: This study demonstrates the utilization of stable spherical covalent organic frameworks (SCOFs) as matrixes for the fabrication of new chiral stationary phases (CSPs). The synthesized SCOF-based CSPs exhibit high resolution abilities for enantiomeric separation in high-performance liquid chromatography (HPLC). Compared to silica-based CSPs, the prepared SCOF-based CSPs show superior acid and base stability.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Nanoscience & Nanotechnology
Qiong Zheng, Jiajia Huang, Yanting He, Huan Huang, Yin Ji, Yongfan Zhang, Zian Lin
Summary: A single-crystalline covalent organic framework (COF-300) packed column was developed for the successful separation of positional isomers in high-performance liquid chromatography (HPLC), demonstrating the great potential of single-crystalline COFs in separation science.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Review
Chemistry, Analytical
Yan Wu, Ning Zhang, Kaixing Luo, Yanjuan Liu, Zhengwu Bai, Sheng Tang
Summary: This article reviews the recent advances in efficient chromatographic separation materials developed in 2020-2021, focusing on their synthesis strategies, performance evaluation, and applications in hydrophilic interaction chromatography and chiral separation. The review provides readers with a comprehensive overview of the significance of these materials in current and future separation technologies.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Analytical
Tiantian Si, Xiaofeng Lu, Haixia Zhang, Shuai Wang, Xiaojing Liang, Yong Guo
Summary: This review provides a brief summary of the performances and recent applications of metal-organic frameworks (MOFs) based core-shell composites as stationary phases in high-performance liquid chromatography. It also discusses in detail the application of MOF-based composites for separating analytes under different conditions.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Meichao Xie, Kaijun Quan, Hui Li, Bei Liu, Jia Chen, Yongliang Yu, Jianhua Wang, Hongdeng Qiu
Summary: A new strategy using non-porous silica (NPS) spheres as support and covalent organic frameworks (COFs) as porous functional shell was developed for liquid chromatography, ensuring the independent effect of COFs on separation. NPS@TPB-DMTP was prepared as proof of concept using 1,3,5-tris(4-aminophenyl)benzene (TPB) and 2,5-dimethoxy-1,4-benzenedicarboxaldehyde (DMTP) as monomers by in situ polymerization on the surface of NPS. This new approach of developing COF-based stationary phases will aid in understanding the impact of COFs on separation.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Analytical
Bin Huang, Kuan Li, Qi-Yu Ma, Tuan-Xiu Xiang, Rui-Xue Liang, Ya-Nan Gong, Bang-Jin Wang, Jun-Hui Zhang, Sheng-Ming Xie, Li-Ming Yuan
Summary: This study demonstrates the use of metallacycles as stationary phases for gas chromatographic (GC) separations. The metallacycle-coated column showed excellent separation performance for various organic isomers and racemic compounds. This work highlights the potential of metallacycles in GC separations and expands their applications in separation science.
ANALYTICAL CHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Robert Berkecz, Gabor Nemeti, Antal Peter, Istvan Ilisz
Summary: Chiral compounds play a crucial role in living organisms, making the enantioseparation of compounds a key task in modern analytical chemistry. High-performance liquid chromatography is the most commonly used method for separating chiral compounds.
Article
Chemistry, Multidisciplinary
Yilun Yan, Xinle Li, Gui Chen, Kai Zhang, Xihao Tang, Shuyuan Zhang, Shengrun Zheng, Jun Fan, Weiguang Zhang, Songliang Cai
Summary: The study developed a novel method for the synthesis of chiral COFs, successfully synthesizing chiral COFs with different functional groups using enantiopure monomers. It was found that through chemical modification, chiral COFs with unprecedented properties could be constructed, maintaining homochirality and crystallinity even after structural changes.
CHINESE CHEMICAL LETTERS
(2021)
Article
Chemistry, Analytical
Zhi-Feng Huang, Wen-Yan Jia, Li-Ming Yuan
Summary: Chiral covalent organic frameworks (CCOFs) are widely used in various fields due to their potential applications in asymmetric catalysis and chiral recognition. This study focuses on the application of CCOFs in chromatographic chiral separation. Three types of CCOFs were synthesized and used as gas chromatography chiral stationary phases (CSPs), showing good chiral selectivity and repeatability. The study expands the range of CCOFs used as CSPs and demonstrates their potential in chromatographic chiral separation.
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
Hai-Long Qian, Fang Liu, Xue Liu, Cheng Yang, Xiu-Ping Yan
Summary: The facile preparation of a chiral COF-monolith with high permeability and mechanical stability through orthogonal experiments was achieved for enantiomeric separation of AAs in HPLC. The resulting monolithic column showed better chiral HPLC separation performance than commercial columns, indicating the potential of chiral COF as a stationary phase for HPLC applications. Thermal dynamic analysis and molecular docking calculations suggested the involvement of stereoscopic interactions in the enantioseparation process.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Chunqiang Liu, Kaijun Quan, Jia Chen, Xiaofeng Shi, Hongdeng Qiu
Summary: Chiral metal organic frameworks (CMOFs), with customizable combination of metal nodes and organic ligands, have attracted increasing attention due to their highly ordered crystal structure and rich adjustable chiral structure. This review discusses the progress of CMOFs and their different types of composites used as chiral stationary phases (CSPs) in liquid chromatography for enantioseparation. The characteristics of CMOFs and their composites are summarized, aiming to provide new ideas for the development of CMOFs with better performance and further promote the application of CMOFs materials in enantioselective high-performance liquid chromatography (HPLC).
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Chemistry, Analytical
Ping Guo, Bao-Yan Yuan, Yun-Yan Yu, Jun-Hui Zhang, Bang-Jin Wang, Sheng-Ming Xie, Li-Ming Yuan
Summary: The chiral COF CTpBD was synthesized and immobilized on the surface of amino functionalized silica to prepare the chiral COF core-shell microsphere composite CTpBD@SiO2, which showed promising performance as a novel chiral stationary phase for HPLC enantioseparation. The CTpBD@SiO2-packed column exhibited high column efficiency, enantioselectivity, and reproducibility in separating various racemates, with resolution values, retention factors, and separation factors reaching desirable levels.
Article
Chemistry, Analytical
Ang Li, Song Xue, Yu Xu, Sihui Ding, Di Wen, Qi Zhang
Summary: The study explores the feasibility of using hydrophobic eutectic solvents (HESs) as pseudo-stationary phases (PSPs) in capillary electrophoresis (CE) for chiral separations. It demonstrates that there is a potential synergistic effect between HESs and traditional chiral selectors, improving enantioseparations of basic drugs.
ANALYTICA CHIMICA ACTA
(2023)
Article
Biochemical Research Methods
Lei Gu, Jin Guan, Ziwei Huang, Hongyi Huo, Shuang Shi, Dongxiang Zhang, Feng Yan
Summary: In this study, a new open-tubular capillary electrochromatography column was prepared using beta-cyclodextrin covalent organic framework as the stationary phase. The effectiveness of chiral separation was evaluated using proton pump inhibitors as model analytes. The results demonstrate the great potential of beta-cyclodextrin covalent organic framework as a chiral-stationary phase for enantioseparation in capillary electrochromatography.
Article
Chemistry, Analytical
Zhihua Song, Yanqin Song, Yinghao Wang, Jinqiu Liu, Yumeng Wang, Wen Lin, Yaqi Wang, Jinhua Li, Jiping Ma, Gangqiang Yang, Lingxin Chen
Summary: In this study, zidovudine imprinted polymers coated silica stationary phases (MIPs/SiO2 SPs) were successfully synthesized and demonstrated superior chromatographic performances in separation of nucleoside analogues and ginsenosides.
Article
Chemistry, Analytical
Yingchun Wang, Zihan Zeng, Liye Yang, Hui Zeng, Yan Li, Qiaosheng Pu, Min Zhang
Summary: We present a novel 3-in-1 detector capable of simultaneously measuring contactless conductivity (C4D), ultraviolet absorbance (UV-AD), and laser-induced fluorescence (LIF) in capillary electrophoresis (CE). The detector features a rectangular detector head assembled with 3D-printed parts, with two electrically conductive parts functioning as a Faraday cage and two high-resolution stereolithography (SLA) printed parts. The detector demonstrated excellent performance in detecting various analytes with LODs of 1.3 μM (C4D), 2.0 μM (UV-AD), and 1 nM (LIF) for fluorescein.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yanan Li, Di Huang, Yiran Pei, Fenglei Quan, Hua Gao, Junli Zhang, Hongwei Hou, Kaixiang Zhang, Jinghong Li
Summary: Site-specific imaging of target genes using CRISPR probes is crucial for understanding gene function and developing tools for gene manipulation. The CasSABER probe allows programmable in situ imaging of low and nonrepetitive regions of a gene. It can specifically light up gene loci bound by dCas9/sgRNA, enabling high-specificity and high-signal-to-noise ratio imaging of fixed cellular gene loci. The CasSABER system also enables adjustable signal amplification, allowing simultaneous visualization of multicopy and single-copy gene loci with similar fluorescence intensity.
ANALYTICAL CHEMISTRY
(2023)
Article
Mathematics, Applied
Yanan Li, Zhijian Yang
Summary: In this paper, the continuity of attractors in time-dependent phase spaces is investigated. Abstract criteria are established for the upper semicontinuity and residual continuity of the pullback D-attractor, as well as an equivalence criterion between their continuity and pullback equiattraction. The notion of pullback D-exponential attractor is proposed and its existence and Holder continuity criterion are established. These results are applied to semilinear damped wave equations with perturbed time-dependent speed of propagation, overcoming the difficulty of model hyperbolicity.
JOURNAL OF MATHEMATICAL ANALYSIS AND APPLICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Fei Yuan, Conghao Shi, Yanan Li, Jian Wang, Di Zhang, Wei Wang, Qiujun Wang, Huan Wang, Zhaojin Li, Bo Wang
Summary: Multipores engineering can effectively improve potassium storage performance through providing adsorption sites and shortened ions diffusion distance. However, the role of macropores in potassium storage has been rarely explored. This study successfully synthesized a superstructure carbon hexahedron with macropores and balanced defects content and graphitization degree. The presence of macropores promotes rapid infiltration of electrolyte ions within the electrode, while the balance between defects and graphitic provides rich adsorption sites and sufficient electron transfer channels. These advantages contribute to a prominent electrochemical performance, including high rate and cycling stability.
Article
Clinical Neurology
Zhiqiang Wu, Jing Wang, Yanan Li, Jianmin Liu, Zijian Kang, Wangjun Yan
Summary: This study constructed a risk scoring model based on lactate metabolism genes in glioma, which could predict the survival of patients and assist clinical oncologists in planning personalized and effective therapeutic regimens.
FRONTIERS IN NEUROLOGY
(2023)
Article
Chemistry, Multidisciplinary
Zhenyu Hao, Hai Zhang, Xiaoli Tang, Lihua Sui, Yanan Li, Shucai Zhang
Summary: This study investigated the crystallization kinetics and stabilization behavior mechanism of different heavy metals in glass-ceramics produced using petrochemical incineration fly ash. The results showed that it is easier to produce the glass ceramics at a temperature of around 850°C, with a low crystallization activation energy of 121.49 kJ/mol. The heavy metals were well solidified and the leaching concentration was significantly lower than the limit specified by governmental agencies, indicating the potential and reliability of converting hazardous petrochemical incineration fly ash into environmentally friendly glass ceramics.
FRONTIERS IN CHEMISTRY
(2023)
Correction
Biochemistry & Molecular Biology
Mengmeng Jin, Hui Zhang, Baijie Xu, Yanan Li, Huiwen Qin, Shuguang Yu, Jie He
Article
Energy & Fuels
Zhiqi Zhao, Xue Xia, Yanan Li, Daiwei Liu, Wei Cai, Chuanxian Li, Guangyu Sun, Bo Yao, Fei Yang
Summary: The effects of DBSA concentration on the stability of emulsions containing both asphaltenes and paraffin wax were investigated at two different temperatures. The results showed that the test temperature had a significant impact on the stability of the emulsion, with the interfacial structure's strength being the main factor at 30℃ and the low-temperature flowability of the oil phase primarily controlling the stability at 15℃.
Review
Chemistry, Applied
Zedong Xiang, Qing Xue, Peng Gao, Haitao Yu, Mingze Wu, Zanzan Zhao, Yanan Li, Shaoping Wang, Jiayu Zhang, Long Dai
Summary: This paper presents a systematic review of the research progress on the enzymatic hydrolysis strategy and structure-activity relationship of antioxidant peptides from edible aquatic animals, especially marine animals, over the last decade. The study reveals that peptides extracted from different organs and tissues have varied antioxidant activity. Additionally, the stability of peptides during gastrointestinal digestion poses a challenge for their application in food and pharmaceutical industries.
Article
Food Science & Technology
Wenjiang Dong, Qidi Hong, Jinhuan Cheng, Hongyan He, Yanan Li, Rongsuo Hu, Yuzhou Long
Summary: This study investigated the oxidation status of solvent-extracted and cold-pressed green coffee oil (GCO) under accelerated storage conditions using proton nuclear magnetic resonance (1H and 13C NMR) spectroscopy. Results showed that the signal intensity of oxidation products gradually increased with oxidation time, while unsaturated fatty acid signals weakened. The NMR system was found to be a fast and convenient tool for monitoring the oxidation process and quality control of GCO.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Environmental Sciences
Zhengyu Wang, Pengxiang Sui, Hongli Lian, Yanan Li, Xiyu Liu, Haoran Xu, Hongyu Zhang, Yingying Xu, Xiangwei Gong, Hua Qi, Ying Jiang
Summary: Understanding the combined effects of tillage and straw incorporation on grain yield and nitrogen fertilizer utilization is crucial for sustainable agriculture in northeastern China. A four-year field experiment showed that plough tillage with straw incorporation (PTS) resulted in higher straw nitrogen uptake and lower nitrogen use efficiency compared to rotary tillage with maize straw incorporation (RTS). Grain yield and nitrogen uptake increased with the nitrogen application rate, but no further increase in yield was observed beyond 187 kg N ha(-1). PTS also led to higher unaccounted nitrogen from applied fertilizer compared to RTS. Overall, the study suggests that tillage with continuous straw incorporation can reduce the amount of nitrogen fertilizer required for maize production.
LAND DEGRADATION & DEVELOPMENT
(2023)
Article
Biochemistry & Molecular Biology
Zhe Li, Weichao Dong, Yanan Li, Xin Liu, Hong Wang, Long Dai, Jiayu Zhang, Shaoping Wang
Summary: In this study, the metabolites of genistin were identified in a hyperlipidemic rat model induced by a high-fat diet. The results showed that genistin could significantly reduce lipid factors, inhibit lipid accumulation in the liver, and reverse liver function abnormalities caused by lipid peroxidation. This study provides the foundation for genistin as a new lipid-lowering agent.
Article
Chemistry, Physical
Yang Li, Ya-Nan Li, Xi-Wu Li, Kai Zhu, Yong-An Zhang, Zhi-Hui Li, Hong-Wei Yan, Kai Wen
Summary: The effects of material removal strategies and initial stress states on the machining deformation of aluminum alloy plates were investigated. Different machining strategies were developed, resulting in significantly different levels of machining deformation. The asymmetric initial stress state had a significant impact on the machining deformation of thick plates. The modeling results for the stress state and machining deformation were accurate and in good accordance with the experimental findings.
Article
Microbiology
Yanan Li, Thomas K. Wood, Weiwei Zhang, Chenghua Li
Summary: We investigated tetracycline-induced persister cells in Vibrio splendidus AJ01 and found that the downregulation of the purine metabolism pathway is associated with lower ATP levels and protein aggresome formation. Inhibiting the purine metabolism pathway increased persister cell formation, reduced intracellular tetracycline concentrations, and increased membrane potential. Our findings demonstrate that the reduction of purine metabolism regulates AJ01 persistence and affects protein aggresome formation and intracellular tetracycline efflux.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Engineering, Chemical
Yanan Li, Yan Wang, Wei Wang, Xiao Yu, Li Zhang, Liu Deng, You-Nian Liu
Summary: Development of heterojunction is an effective strategy to improve the hydrogen production performance of photocatalysts. The fabrication of a 2D/2D Z-scheme heterojunction-coupled Zn0.4Cd0.6S with g-C3N4 by in situ hydrothermal approach is reported in this study. The heterojunction with full contact and strong interfacial interaction enhances the charge transfer and spatial separation of photogenerated charges. Under visible-light irradiation, the optimized catalyst exhibits high hydrogen production without any cocatalysts, outperforming the g-C3N4 photocatalyst with Pt cocatalyst. The catalyst also shows good long-term stability, making it a promising photocatalyst for hydrogen generation.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
