Reconstruction of Coupled Intra- and Interdomain Protein Motion from Nuclear and Electron Magnetic Resonance

Inference of Joint Conformational Distributions from Separately Acquired Experimental Measurements

(2021) Jennifer M. Hays et al.   Journal of Physical Chemistry Letters

Protein Allostery at Atomic Resolution

(2020) Dean Strotz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Compaction of RNA Duplexes in the Cell

(2020) Alberto Collauto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Coupled intra- and interdomain dynamics support domain cross-talk in Pin1

(2020) Meiling Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uncorrelated Effect of Interdomain Contact on Pin1 Isomerase Activity Reveals Positive Catalytic Cooperativity

(2019) Wenkai Zhu et al.   Journal of Physical Chemistry Letters

Structure determination using solution NMR: Is it worth the effort?

(2019) Koh Takeuchi et al.   JOURNAL OF MAGNETIC RESONANCE

Assembling multidomain protein structures through analogous global structural alignments

(2019) Xiaogen Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial domain organization in the HIV-1 reverse transcriptase p66 homodimer precursor probed by double electron-electron resonance EPR

(2019) Thomas Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activity and Affinity of Pin1 Variants

(2019) Alexandra Born et al.   MOLECULES

Structure and function of the human parvulins Pin1 and Par14/17

(2018) Anja Matena et al.   BIOLOGICAL CHEMISTRY

Extending the Applicability of Exact Nuclear Overhauser Enhancements to Large Proteins and RNA

(2018) Parker J. Nichols et al.   CHEMBIOCHEM

Enhanced Sampling of Interdomain Motion Using Map-Restrained Langevin Dynamics and NMR: Application to Pin1

(2018) Jill J. Bouchard et al.   JOURNAL OF MOLECULAR BIOLOGY

Continuous Interdomain Orientation Distributions Reveal Components of Binding Thermodynamics

(2018) Yang Qi et al.   JOURNAL OF MOLECULAR BIOLOGY

Same but not alike: Structure, flexibility and energetics of domains in multi-domain proteins are influenced by the presence of other domains

(2018) Sneha Vishwanath et al.   PLoS Computational Biology

Propagated Perturbations from a Peripheral Mutation Show Interactions Supporting WW Domain Thermostability

(2018) Meiling Zhang et al.   STRUCTURE

Backbone and side-chain chemical shift assignments of full-length, apo, human Pin1, a phosphoprotein regulator with interdomain allostery

(2018) Alexandra Born et al.   Biomolecular NMR Assignments

Dynamic Allostery Modulates Catalytic Activity by Modifying the Hydrogen Bonding Network in the Catalytic Site of Human Pin1

(2017) Jing Wang et al.   MOLECULES

The Exact Nuclear Overhauser Enhancement: Recent Advances

(2017) Parker Nichols et al.   MOLECULES

Artefact suppression in 5-pulse double electron electron resonance for distance distribution measurements

(2017) Frauke D. Breitgoff et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

MMM: A toolbox for integrative structure modeling

(2017) Gunnar Jeschke   PROTEIN SCIENCE

Characterization of the Domain Orientations of E. coli 5′-Nucleotidase by Fitting an Ensemble of Conformers to DEER Distance Distributions

(2016) Ulrike Krug et al.   STRUCTURE

Allosteric Breakage of the Hydrogen Bond within the Dual-Histidine Motif in the Active Site of Human Pin1 PPIase

(2015) Jing Wang et al.   BIOCHEMISTRY

AIDA: ab initio domain assembly for automated multi-domain protein structure prediction and domain–domain interaction prediction

(2015) Dong Xu et al.   BIOINFORMATICS

Extending the eNOE data set of large proteins by evaluation of NOEs with unresolved diagonals

(2015) Celestine N. Chi et al.   JOURNAL OF BIOMOLECULAR NMR

Complementarity and congruence between exact NOEs and traditional NMR probes for spatial decoding of protein dynamics

(2015) Beat Vögeli et al.   JOURNAL OF STRUCTURAL BIOLOGY

Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease

(2015) Chun-Hau Chen et al.   NEUROBIOLOGY OF DISEASE

Two Pathways Mediate Interdomain Allosteric Regulation in Pin1

(2015) Jingjing Guo et al.   STRUCTURE

Combination of X-ray crystallography, SAXS and DEER to obtain the structure of the FnIII-3,4 domains of integrin α6β4

(2015) Noelia Alonso-García et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Cysteine-Mediated Dynamic Hydrogen-Bonding Network in the Active Site of Pin1

(2014) Arghya Barman et al.   BIOCHEMISTRY

The C113D Mutation in Human Pin1 Causes Allosteric Structural Changes in the Phosphate Binding Pocket of the PPIase Domain through the Tug of War in the Dual-Histidine Motif

(2014) Ning Xu et al.   BIOCHEMISTRY

Towards a true protein movie: A perspective on the potential impact of the ensemble-based structure determination using exact NOEs

(2014) Beat Vögeli et al.   JOURNAL OF MAGNETIC RESONANCE

Interdomain Interactions Support Interdomain Communication in Human Pin1

(2013) Kimberly A. Wilson et al.   BIOCHEMISTRY

Targeted conformational search with map-restrained self-guided Langevin dynamics: Application to flexible fitting into electron microscopic density maps

(2013) Xiongwu Wu et al.   JOURNAL OF STRUCTURAL BIOLOGY

NMR spectroscopy on domain dynamics in biomacromolecules

(2013) Yury E. Shapiro   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

The nuclear Overhauser effect from a quantitative perspective

(2013) Beat Vögeli   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Transient Domain Interactions Enhance the Affinity of the Mitotic Regulator Pin1 toward Phosphorylated Peptide Ligands

(2013) Anja Matena et al.   STRUCTURE

Improved Sensitivity for Long-Distance Measurements in Biomolecules: Five-Pulse Double Electron–Electron Resonance

(2012) Peter P. Borbat et al.   Journal of Physical Chemistry Letters

Multiple-state ensemble structure determination from eNOE spectroscopy

(2012) Beat Vögeli et al.   MOLECULAR PHYSICS

A rigid disulfide-linked nitroxide side chain simplifies the quantitative analysis of PRE data

(2011) Nicolas L. Fawzi et al.   JOURNAL OF BIOMOLECULAR NMR

Dead-time free measurement of dipole–dipole interactions between electron spins

(2011) M. Pannier et al.   JOURNAL OF MAGNETIC RESONANCE

Transient, Sparsely Populated Compact States of Apo and Calcium-Loaded Calmodulin Probed by Paramagnetic Relaxation Enhancement: Interplay of Conformational Selection and Induced Fit

(2011) Nicholas J. Anthis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Paramagnetic-Based NMR Restraints Lift Residual Dipolar Coupling Degeneracy in Multidomain Detergent-Solubilized Membrane Proteins

(2011) Lei Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereospecific gating of functional motions in Pin1

(2011) A. T. Namanja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stability of domain structures in multi-domain proteins

(2011) Ramachandra M. Bhaskara et al.   Scientific Reports

Exact Distances and Internal Dynamics of Perdeuterated Ubiquitin from NOE Buildups

(2009) Beat Vögeli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Orientation of a Tandem POTRA Domain Pair, of the Beta-Barrel Assembly Protein BamA, Determined by PELDOR Spectroscopy

(2009) R. Ward et al.   STRUCTURE