Journal
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
Volume 36, Issue 2, Pages 215-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.iac.2015.12.001
Keywords
Rhinitis; Endotypes; Phenotypes; Pathophysiology; Symptoms
Categories
Funding
- GSK
- Nestle
- Merck
- AbbVie
- Sanofi
- Menarini
- Meda
- Novartis
- ALK-Abello
- Allergopharma
- Uriach
- Stallergenes
- MSD
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Rhinitis is often seen as posing a small burden. However, rhinitis is a complex disease that is underpinned by a plethora of different mechanisms and causes. Rhinitis is frequently associated with other comorbid conditions but, by itself, is a source of considerable morbidity for patients and creates a significant financial burden on health systems worldwide. This article approaches this condition from both a phenotypic and mechanistic standpoint, focusing on the complexity of characterizing these subtypes. Developing a clearer demarcation of the currently obscure rhinitis phenotypes and endotypes will substantially improve their future prevention and treatment.
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