Vitamin D immunoregulation through dendritic cells

The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity

(2015) Andrew L. Croxford et al.   IMMUNITY

GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c+MHCII+ Macrophages and Dendritic Cells

(2015) Julie Helft et al.   IMMUNITY

Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow

(2015) Jaeyop Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Circulating precursors of human CD1c+and CD141+dendritic cells

(2015) Gaëlle Breton et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Generation and transcriptional programming of intestinal dendritic cells: essential role of retinoic acid

(2015) R Zeng et al.   Mucosal Immunology

Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow

(2015) Andreas Schlitzer et al.   NATURE IMMUNOLOGY

Control of adaptive immunity by the innate immune system

(2015) Akiko Iwasaki et al.   NATURE IMMUNOLOGY

Regulation of Dendritic Cell Function by Vitamin D

(2015) Myriam Barragan et al.   Nutrients

The vitamin D receptor turns off chronically activated T cells

(2014) Margherita T. Cantorna et al.   Annals of the New York Academy of Sciences

Regulation of CYP27B1 and CYP24A1 hydroxylases limits cell-autonomous activation of vitamin D in dendritic cells

(2014) Rhiannon Kundu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human Dermal CD14 + Cells Are a Transient Population of Monocyte-Derived Macrophages

(2014) Naomi McGovern et al.   IMMUNITY

1,25-Dihydroxyvitamin D3 Promotes Tolerogenic Dendritic Cells with Functional Migratory Properties in NOD Mice

(2014) G. B. Ferreira et al.   JOURNAL OF IMMUNOLOGY

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

(2014) Bart Everts et al.   NATURE IMMUNOLOGY

Adaptation of Innate Lymphoid Cells to a Micronutrient Deficiency Promotes Type 2 Barrier Immunity

(2014) S. P. Spencer et al.   SCIENCE

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Tolerogenic dendritic cell vaccines to treat autoimmune diseases: Can the unattainable dream turn into reality?

(2013) Ilse Van Brussel et al.   AUTOIMMUNITY REVIEWS

The Implication of Vitamin D and Autoimmunity: a Comprehensive Review

(2013) Chen-Yen Yang et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Control of T Helper 2 Responses by Transcription Factor IRF4-Dependent Dendritic Cells

(2013) Yan Gao et al.   IMMUNITY

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

Dendritic-Cell-Based Therapeutic Cancer Vaccines

(2013) Karolina Palucka et al.   IMMUNITY

The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology

(2013) Mate Kiss et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Retinoic acid controls the homeostasis of pre-cDC–derived splenic and intestinal dendritic cells

(2013) Christopher A. Klebanoff et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human CD1c+ Myeloid Dendritic Cells Acquire a High Level of Retinoic Acid-Producing Capacity in Response to Vitamin D3

(2013) T. Sato et al.   JOURNAL OF IMMUNOLOGY

Canonical and Noncanonical Wnt Proteins Program Dendritic Cell Responses for Tolerance

(2013) C. Oderup et al.   JOURNAL OF IMMUNOLOGY

Vitamin D Regulates the Gut Microbiome and Protects Mice from Dextran Sodium Sulfate–Induced Colitis

(2013) Jot Hui Ooi et al.   JOURNAL OF NUTRITION

Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice

(2013) Payal B Watchmaker et al.   NATURE IMMUNOLOGY

Origin of monocytes and macrophages in a committed progenitor

(2013) Jan Hettinger et al.   NATURE IMMUNOLOGY

Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation

(2013) Bryan Vander Lugt et al.   NATURE IMMUNOLOGY

Intradermal application of vitamin D3 increases migration of CD14+dermal dendritic cells and promotes the development of Foxp3+regulatory T cells

(2013) Ghaith Bakdash et al.   Human Vaccines & Immunotherapeutics

Regulatory Multitasking of Tolerogenic Dendritic Cells – Lessons Taken from Vitamin D3-Treated Tolerogenic Dendritic Cells

(2013) Tatjana Nikolic et al.   Frontiers in Immunology

The Vitamin D Receptor and T Cell Function

(2013) Martin Kongsbak et al.   Frontiers in Immunology

Extrarenal expression of the 25-hydroxyvitamin D-1-hydroxylase

(2012) J.S. Adams et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells

(2012) B. Everts et al.   BLOOD

Resident CD141 (BDCA3)+dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation

(2012) Chung-Ching Chu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Availability of 25-Hydroxyvitamin D3 to APCs Controls the Balance between Regulatory and Inflammatory T Cell Responses

(2012) L. E. Jeffery et al.   JOURNAL OF IMMUNOLOGY

A randomised, double blind, placebo controlled trial with vitamin D3as an add on treatment to interferon β-1b in patients with multiple sclerosis

(2012) Merja Soilu-Hänninen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

1α,25-Dihydroxyvitamin D3 and its analogs as modulators of human dendritic cells: A comparison dose-titration study

(2012) Gabriela Bomfim Ferreira et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Retinoic acid regulates the development of a gut-homing precursor for intestinal dendritic cells

(2012) R Zeng et al.   Mucosal Immunology

Expression of Retinaldehyde Dehydrogenase Enzymes in Mucosal Dendritic Cells and Gut-Draining Lymph Node Stromal Cells Is Controlled by Dietary Vitamin A

(2011) R. Molenaar et al.   JOURNAL OF IMMUNOLOGY

Bile retinoids imprint intestinal CD103+ dendritic cells with the ability to generate gut-tropic T cells

(2011) E Jaensson-Gyllenbäck et al.   Mucosal Immunology

Vitamin D Receptor Negatively Regulates Bacterial-Stimulated NF-κB Activity in Intestine

(2010) Shaoping Wu et al.   AMERICAN JOURNAL OF PATHOLOGY

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

(2010) C. M. Krawczyk et al.   BLOOD

Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

(2010) Jérôme Cros et al.   IMMUNITY

Lineage-specific Effects of 1,25-Dihydroxyvitamin D3on the Development of Effector CD4 T Cells

(2010) Matthew T. Palmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lack of Retinoic Acid Leads to Increased Langerin-Expressing Dendritic Cells in Gut-Associated Lymphoid Tissues

(2009) Sun–Young Chang et al.   GASTROENTEROLOGY

1,25-Dihydroxyvitamin D3 Is an Autonomous Regulator of the Transcriptional Changes Leading to a Tolerogenic Dendritic Cell Phenotype

(2009) L. Szeles et al.   JOURNAL OF IMMUNOLOGY

TLR-Induced Local Metabolism of Vitamin D3 Plays an Important Role in the Diversification of Adaptive Immune Responses

(2009) E. Y. Enioutina et al.   JOURNAL OF IMMUNOLOGY

Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning

(2009) I D Iliev et al.   Mucosal Immunology

Proteome analysis demonstrates profound alterations in human dendritic cell nature by TX527, an analogue of vitamin D

(2009) Gabriela Bomfim Ferreira et al.   PROTEOMICS

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

(2008) Roger Bouillon et al.   ENDOCRINE REVIEWS

Vitamin D as an immune modulator in multiple sclerosis, a review

(2008) Joost Smolders et al.   JOURNAL OF NEUROIMMUNOLOGY

Environmental cues, dendritic cells and the programming of tissue-selective lymphocyte trafficking

(2008) Hekla Sigmundsdottir et al.   NATURE IMMUNOLOGY

TLR ligands that stimulate the metabolism of vitamin D3 in activated murine dendritic cells can function as effective mucosal adjuvants to subcutaneously administered vaccines

(2008) Elena Y. Enioutina et al.   VACCINE