SHARPIN controls the development of regulatory T cells

Regulatory T Cell Reprogramming toward a Th2-Cell-like Lineage Impairs Oral Tolerance and Promotes Food Allergy

(2015) Magali Noval Rivas et al.   IMMUNITY

Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system

(2015) Katsuhiro Sasaki et al.   IMMUNOLOGICAL REVIEWS

A catalytic-independent role for the LUBAC in NF- B activation upon antigen receptor engagement and in lymphoma cells

(2014) S. M. Dubois et al.   BLOOD

Continuous T Cell Receptor Signals Maintain a Functional Regulatory T Cell Pool

(2014) J. Christoph Vahl et al.   IMMUNITY

Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance

(2014) Fang Yu et al.   NATURE IMMUNOLOGY

Essential Role of the Linear Ubiquitin Chain Assembly Complex in Lymphoma Revealed by Rare Germline Polymorphisms

(2014) Y. Yang et al.   Cancer Discovery

Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells

(2013) Yoshiteru Sasaki et al.   EMBO JOURNAL

Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis

(2013) Takashi Sekiya et al.   NATURE IMMUNOLOGY

'Nurr'ishing Treg cells: Nr4a transcription factors control Foxp3 expression

(2013) Hozefa S Bandukwala et al.   NATURE IMMUNOLOGY

A Broad Range of Self-Reactivity Drives Thymic Regulatory T Cell Selection to Limit Responses to Self

(2012) Hyang-Mi Lee et al.   IMMUNITY

Negative regulators of integrin activity

(2012) J. Pouwels et al.   JOURNAL OF CELL SCIENCE

SHARPIN is a key regulator of immune and inflammatory responses

(2012) Zhe Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

NIK Prevents the Development of Hypereosinophilic Syndrome-like Disease in Mice Independent of IKK  Activation

(2012) H. Hacker et al.   JOURNAL OF IMMUNOLOGY

Foxp3+ Cells Control Th2 Responses in a Murine Model of Atopic Dermatitis

(2012) Nanna Fyhrquist et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Regulatory T cells and Foxp3

(2011) Alexander Y. Rudensky   IMMUNOLOGICAL REVIEWS

T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse

(2011) Amy E. Moran et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SHARPIN is an endogenous inhibitor of β1-integrin activation

(2011) Juha K. Rantala et al.   NATURE CELL BIOLOGY

Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses

(2011) D. E. Zak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional regulation of Foxp3 in regulatory T cells

(2010) He Haiqi et al.   IMMUNOBIOLOGY

Differential requirement for CARMA1 in agonist-selected T-cell development

(2009) Benjamin D. Medoff et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nuclear Factor-κB Modulates Regulatory T Cell Development by Directly Regulating Expression of Foxp3 Transcription Factor

(2009) Meixiao Long et al.   IMMUNITY

Development of Foxp3+ Regulatory T Cells Is Driven by the c-Rel Enhanceosome

(2009) Qingguo Ruan et al.   IMMUNITY

c-Rel is required for the development of thymic Foxp3+CD4 regulatory T cells

(2009) Iwao Isomura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Regulatory T Cells Do Not Require Stimulation through Their TCR to Suppress

(2009) A. L. Szymczak-Workman et al.   JOURNAL OF IMMUNOLOGY

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

(2009) Ye Zheng et al.   NATURE

Commitment to the Regulatory T Cell Lineage Requires CARMA1 in the Thymus but Not in the Periphery

(2009) Michael J Barnes et al.   PLOS BIOLOGY

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Differential requirement of PKC-θ in the development and function of natural regulatory T cells

(2008) Sonal Gupta et al.   MOLECULAR IMMUNOLOGY