Thymocytes self-renewal: a major hope or a major threat?

Recent advances in understanding the pathophysiology of primary T cell immunodeficiencies

(2015) Alain Fischer   TRENDS IN MOLECULAR MEDICINE

Cell competition is a tumour suppressor mechanism in the thymus

(2014) Vera C. Martins et al.   NATURE

A Modified γ-Retrovirus Vector for X-Linked Severe Combined Immunodeficiency

(2014) Salima Hacein-Bey-Abina et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gene Therapy for Wiskott-Aldrich Syndrome--Long-Term Efficacy and Genotoxicity

(2014) C. J. Braun et al.   Science Translational Medicine

Single-Cell Analysis of Thymocyte Differentiation: Identification of Transcription Factor Interactions and a Major Stochastic Component in αβ-Lineage Commitment

(2013) Amine Boudil et al.   PLoS One

Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome

(2013) A. Aiuti et al.   SCIENCE

Thymocytes may persist and differentiate without any input from bone marrow progenitors

(2012) Laetitia Peaudecerf et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thymus-autonomous T cell development in the absence of progenitor import

(2012) Vera C. Martins et al.   JOURNAL OF EXPERIMENTAL MEDICINE

First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases

(2010) M. L. Markert et al.   BLOOD

Transplantation of hematopoietic stem cells in human severe combined immunodeficiency: longterm outcomes

(2010) Rebecca H. Buckley   IMMUNOLOGIC RESEARCH

Advances in adoptive immunotherapy to accelerate T-cellular immune reconstitution after HLA-incompatible hematopoietic stem cell transplantation

(2010) Christian Reimann et al.   Immunotherapy

The role of the gut as a primary lymphoid organ: CD8αα intraepithelial T lymphocytes in euthymic mice derive from very immature CD44+ thymocyte precursors

(2010) L Peaudecerf et al.   Mucosal Immunology

Immune reconstitution after haematopoietic stem cell transplantation: obstacles and anticipated progress

(2009) Marina Cavazzana-Calvo et al.   CURRENT OPINION IN IMMUNOLOGY

Thymus development and function

(2008) Thomas Boehm   CURRENT OPINION IN IMMUNOLOGY

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

(2008) Steven J. Howe et al.   JOURNAL OF CLINICAL INVESTIGATION

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

(2008) Salima Hacein-Bey-Abina et al.   JOURNAL OF CLINICAL INVESTIGATION

Lymphoid reconstitution following hematopoietic stem cell transplantation

(2008) Georg A. Holländer   Seminars in Immunopathology