Glutamate Buffering Capacity and Blood-Brain Barrier Protection of Opioid Receptor Agonists Biphalin and Nociceptin

Novel approaches for the delivery of therapeutics in ischemic stroke

(2020) Saeideh Nozohouri et al.   DRUG DISCOVERY TODAY

Management of cancer pain in adult patients: ESMO Clinical Practice Guidelines†

(2018) M Fallon et al.   ANNALS OF ONCOLOGY

The neuroprotective role of the brain opioid system in stroke injury

(2018) Bhuvaneshwar Vaidya et al.   DRUG DISCOVERY TODAY

Novel role of the nociceptin system as a regulator of glutamate transporter expression in developing astrocytes

(2017) Logan C. Meyer et al.   GLIA

Biphalin, a Dimeric Enkephalin, Alleviates LPS-Induced Activation in Rat Primary Microglial Cultures in Opioid Receptor-Dependent and Receptor-Independent Manners

(2017) Katarzyna Popiolek-Barczyk et al.   NEURAL PLASTICITY

Biphalin: The Foundation of Bivalent Ligands

(2016) Scott M. Cowell et al.   CURRENT MEDICINAL CHEMISTRY

Glutamate Induces Blood–Brain Barrier Permeability through Activation of N -Methyl-D-Aspartate Receptors

(2016) Kristiana Xhima et al.   JOURNAL OF NEUROSCIENCE

In vitro and in vivo efficacy of a potent opioid receptor agonist, biphalin, compared to subtype-selective opioid receptor agonists for stroke treatment

(2015) Li Yang et al.   BRAIN RESEARCH

Glioblastoma cells induce differential glutamatergic gene expressions in human tumor-associated microglia/macrophages and monocyte-derived macrophages

(2015) Judy Choi et al.   CANCER BIOLOGY & THERAPY

Multiplex Brain Proteomic Analysis Revealed the Molecular Therapeutic Effects of Buyang Huanwu Decoction on Cerebral Ischemic Stroke Mice

(2015) Hong-Jhang Chen et al.   PLoS One

δ-Opioid receptors up-regulate excitatory amino acid transporters in mouse astrocytes

(2014) Jianfeng Liang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity

(2014) Yao Yao et al.   Nature Communications

Current Research on Opioid Receptor Function

(2012) Yuan Feng et al.   CURRENT DRUG TARGETS

Analgesia or Addiction?: Implications for Morphine Use after Spinal Cord Injury

(2012) Sarah A. Woller et al.   JOURNAL OF NEUROTRAUMA

Permeability of Endothelial and Astrocyte Cocultures: In Vitro Blood–Brain Barrier Models for Drug Delivery Studies

(2010) Guanglei Li et al.   ANNALS OF BIOMEDICAL ENGINEERING

Pharmacological evaluation of glutamate transporter 1 (GLT-1) mediated neuroprotection following cerebral ischemia/reperfusion injury

(2010) Rajkumar Verma et al.   EUROPEAN JOURNAL OF PHARMACOLOGY