Development of PBPK model for intra-articular injection in human: methotrexate solution and rheumatoid arthritis case study

Physiologically Based Pharmacokinetic Model to Support Ophthalmic Suspension Product Development

(2020) Maxime Le Merdy et al.   AAPS Journal

Rheumatoid Arthritis

(2019) Jeffrey A. Sparks   ANNALS OF INTERNAL MEDICINE

Application of Mechanistic Ocular Absorption Modeling and Simulation to Understand the Impact of Formulation Properties on Ophthalmic Bioavailability in Rabbits: a Case Study Using Dexamethasone Suspension

(2019) Maxime Le Merdy et al.   AAPS Journal

Intra-articular drug delivery systems for joint diseases

(2018) Muhammad Farooq Rai et al.   CURRENT OPINION IN PHARMACOLOGY

Rheumatoid arthritis

(2018) Josef S. Smolen et al.   Nature Reviews Disease Primers

Methotrexate mechanism in treatment of rheumatoid arthritis

(2018) Benjamin Friedman et al.   JOINT BONE SPINE

Contrast-enhanced MRI findings of the knee in healthy children; establishing normal values

(2017) Robert Hemke et al.   EUROPEAN RADIOLOGY

Rheumatoid arthritis

(2016) Josef S Smolen et al.   LANCET

Development of a Novel Oral Cavity Compartmental Absorption and Transit Model for Sublingual Administration: Illustration with Zolpidem

(2015) Binfeng Xia et al.   AAPS Journal

Physiologically based and population PK modeling in optimizing drug development: A predict-learn-confirm analysis

(2015) A Suri et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Complex function of the knee joint: the current understanding of the knee

(2015) Michael T. Hirschmann et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Intra-articular and soft tissue injections, a systematic review of relative efficacy of various corticosteroids

(2014) Neha Garg et al.   CLINICAL RHEUMATOLOGY

Clinical endpoint sensitivity in rheumatoid arthritis: modeling and simulation

(2014) Lian Ma et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Evidence-Based Knee Injections for the Management of Arthritis

(2012) Olivia T. Cheng et al.   PAIN MEDICINE

Aspirin alters methotrexate disposition in rheumatoid arthritis patients

(2010) Clinton F. Stewart et al.   ARTHRITIS AND RHEUMATISM

Local effects of intra-articular corticosteroids

(2010) George S. Habib et al.   CLINICAL RHEUMATOLOGY

A Biomechanical Triphasic Approach to the Transport of Nondilute Solutions in Articular Cartilage

(2009) Alireza Abazari et al.   BIOPHYSICAL JOURNAL

Modeling Corticosteroid Effects in a Rat Model of Rheumatoid Arthritis I: Mechanistic Disease Progression Model for the Time Course of Collagen-Induced Arthritis in Lewis Rats

(2008) J. C. Earp et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Modeling Corticosteroid Effects in a Rat Model of Rheumatoid Arthritis II: Mechanistic Pharmacodynamic Model for Dexamethasone Effects in Lewis Rats with Collagen-Induced Arthritis

(2008) J. C. Earp et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS