Differential Activity of APOBEC3F, APOBEC3G, and APOBEC3H in the Restriction of HIV-2

Deamination hotspots among APOBEC3 family members are defined by both target site sequence context and ssDNA secondary structure

(2019) Yumeng Z McDaniel et al.   NUCLEIC ACIDS RESEARCH

90-90-90 for HIV-2? Ending the HIV-2 epidemic by enhancing care and clinical management of patients infected with HIV-2

(2018) Geoffrey S Gottlieb et al.   Lancet HIV

Single-Strand Consensus Sequencing Reveals that HIV Type but not Subtype Significantly Impacts Viral Mutation Frequencies and Spectra

(2017) Jonathan M.O. Rawson et al.   JOURNAL OF MOLECULAR BIOLOGY

Hiv-2 molecular epidemiology

(2016) Benoit Visseaux et al.   INFECTION GENETICS AND EVOLUTION

APOBEC3G and APOBEC3F Act in Concert To Extinguish HIV-1 Replication

(2016) John F. Krisko et al.   JOURNAL OF VIROLOGY

Minimal Contribution of APOBEC3-Induced G-to-A Hypermutation to HIV-1 Recombination and Genetic Variation

(2016) Krista A. Delviks-Frankenberry et al.   PLoS Pathogens

APOBEC3G-Mediated G-to-A Hypermutation of the HIV-1 Genome: The Missing Link in Antiviral Molecular Mechanisms

(2016) Ayaka Okada et al.   Frontiers in Microbiology

Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage

(2015) Claudia Alteri et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Infection with human retroviruses other than HIV-1: HIV-2, HTLV-1, HTLV-2, HTLV-3 and HTLV-4

(2015) David Nicolás et al.   Expert Review of Anti-Infective Therapy

Impact of APOBEC Mutations on CD8+ T Cell Recognition of HIV Epitopes Varies Depending on the Restricting HLA

(2015) Krista D. Squires et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Natural Polymorphisms and Oligomerization of Human APOBEC3H Contribute to Single-stranded DNA Scanning Ability

(2015) Yuqing Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 and HIV-2 exhibit similar mutation frequencies and spectra in the absence of G-to-A hypermutation

(2015) Jonathan M O Rawson et al.   Retrovirology

APOBECs and virus restriction

(2015) Reuben S. Harris et al.   VIROLOGY

Promiscuous RNA Binding Ensures Effective Encapsidation of APOBEC3 Proteins by HIV-1

(2015) Luis Apolonia et al.   PLoS Pathogens

Single-Cell and Single-Cycle Analysis of HIV-1 Replication

(2015) Mowgli Holmes et al.   PLoS Pathogens

Novel inhibitors of human immunodeficiency virus type 2 infectivity

(2014) L. B. Beach et al.   JOURNAL OF GENERAL VIROLOGY

HIV-1 and HIV-2 Vif Interact with Human APOBEC3 Proteins Using Completely Different Determinants

(2014) J. L. Smith et al.   JOURNAL OF VIROLOGY

Positioning of APOBEC3G/F Mutational Hotspots in the Human Immunodeficiency Virus Genome Favors Reduced Recognition by CD8+ T Cells

(2014) Mahdis Monajemi et al.   PLoS One

Natural Polymorphisms in Human APOBEC3H and HIV-1 Vif Combine in Primary T Lymphocytes to Affect Viral G-to-A Mutation Levels and Infectivity

(2014) Eric W. Refsland et al.   PLoS Genetics

Different Modes of Retrovirus Restriction by Human APOBEC3A and APOBEC3G In Vivo

(2014) Spyridon Stavrou et al.   PLoS Pathogens

APOBEC3D and APOBEC3F Potently Promote HIV-1 Diversification and Evolution in Humanized Mouse Model

(2014) Kei Sato et al.   PLoS Pathogens

5,6-Dihydro-5-aza-2′-deoxycytidine potentiates the anti-HIV-1 activity of ribonucleotide reductase inhibitors

(2013) Jonathan M. Rawson et al.   BIOORGANIC & MEDICINAL CHEMISTRY

HIV-1 Vif Adaptation to Human APOBEC3H Haplotypes

(2013) Marcel Ooms et al.   Cell Host & Microbe

Multiple APOBEC3 Restriction Factors for HIV-1 and One Vif to Rule Them All

(2013) Belete A. Desimmie et al.   JOURNAL OF MOLECULAR BIOLOGY

Variation of HIV-1 Mutation Spectra among Cell Types

(2013) C. M. Holtz et al.   JOURNAL OF VIROLOGY

Binding of RNA by APOBEC3G controls deamination-independent restriction of retroviruses

(2013) Kasandra Bélanger et al.   NUCLEIC ACIDS RESEARCH

APOBEC3G cytosine deamination hotspots are defined by both sequence context and single-stranded DNA secondary structure

(2013) Colleen M. Holtz et al.   NUCLEIC ACIDS RESEARCH

Retroviral Restriction Factor APOBEC3G Delays the Initiation of DNA Synthesis by HIV-1 Reverse Transcriptase

(2013) Madison B. Adolph et al.   PLoS One

Identification and antiviral activity of common polymorphisms in the APOBEC3 locus in human populations

(2013) Nisha K. Duggal et al.   VIROLOGY

Catalytic activity of APOBEC3F is required for efficient restriction of Vif-deficient human immunodeficiency virus

(2013) John S. Albin et al.   VIROLOGY

Human APOBEC3G-mediated hypermutation is associated with antiretroviral therapy failure in HIV-1 subtype C-infected individuals

(2013) Ujjwal Neogi et al.   Journal of the International AIDS Society

APOBEC3G Restricts HIV-1 to a Greater Extent than APOBEC3F and APOBEC3DE in Human Primary CD4+ T Cells and Macrophages

(2012) C. Chaipan et al.   JOURNAL OF VIROLOGY

Suppression of HIV-1 Infection by APOBEC3 Proteins in Primary Human CD4+T Cells Is Associated with Inhibition of Processive Reverse Transcription as Well as Excessive Cytidine Deamination

(2012) Kieran Gillick et al.   JOURNAL OF VIROLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Reduced APOBEC3H Variant Anti-Viral Activities Are Associated with Altered RNA Binding Activities

(2012) Anjie Zhen et al.   PLoS One

The Breadth of Antiviral Activity of Apobec3DE in Chimpanzees Has Been Driven by Positive Selection

(2011) N. K. Duggal et al.   JOURNAL OF VIROLOGY

Human and Rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H Demonstrate a Conserved Capacity To Restrict Vif-Deficient HIV-1

(2011) J. F. Hultquist et al.   JOURNAL OF VIROLOGY

Polymorphism in Human APOBEC3H Affects a Phenotype Dominant for Subcellular Localization and Antiviral Activity

(2011) M. M. H. Li et al.   JOURNAL OF VIROLOGY

APOBEC3G Contributes to HIV-1 Variation through Sublethal Mutagenesis

(2010) H. A. Sadler et al.   JOURNAL OF VIROLOGY

Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction

(2010) Eric W. Refsland et al.   NUCLEIC ACIDS RESEARCH

Analysis of the Percentage of Human Immunodeficiency Virus Type 1 Sequences That Are Hypermutated and Markers of Disease Progression in a Longitudinal Cohort, Including One Individual with a Partially Defective Vif

(2009) A. Piantadosi et al.   JOURNAL OF VIROLOGY

Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases

(2009) Luis Menéndez-Arias   Viruses-Basel

The Level of APOBEC3G (hA3G)-Related G-to-A Mutations Does Not Correlate with Viral Load in HIV Type 1-Infected Individuals

(2008) Nzovu K. Ulenga et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Human Immunodeficiency Virus (HIV) Type 1 Proviral Hypermutation Correlates with CD4 Count in HIV-Infected Women from Kenya

(2008) A. M. Land et al.   JOURNAL OF VIROLOGY

APOBEC3G Inhibits Elongation of HIV-1 Reverse Transcripts

(2008) Kate N. Bishop et al.   PLoS Pathogens