4.7 Article

Mechanically durable antibacterial nanocoatings based on zwitterionic copolymers containing dopamine segments

Journal

JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
Volume 89, Issue -, Pages 233-241

Publisher

JOURNAL MATER SCI TECHNOL
DOI: 10.1016/j.jmst.2020.11.031

Keywords

Antibacterial surface; Zwitterionic; Polymers; Coatings

Funding

  1. National Natu-ral Science Foundation of China [51771029, 51771122]
  2. Shanghai International Science and Technology CooperationProject [17520731800]
  3. China Postdoctoral Science Foundation [2019M660453]

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Developing effective and durable antibacterial surfaces is crucial for surgical tools and biomedical implants. Zwitterionic copolymers with dopamine segments showed superior stability and mechanical durability on stainless steel surfaces, especially at a molar ratio of 8:2, exhibiting excellent and lasting antibacterial performance.
Developing an effective and durable antibacterial surface is important for surgical tools and biomedical implants. In this work, a zwitterionic copolymer containing catechol groups as biomimetic anchoring segments was coated onto 316 L stainless steel via drop-casting. Energy-dispersive X-ray spectroscopy (EDS) and water contact angle (WCA) measurements indicated that the coatings made of the copolymers containing zwitterionic and dopamine segments at the molar ratios of 8:2 and 6:4 exhibited stronger stability and mechanical durability than the one at 9:1 after inducing tape-peeling and ultrasonication damage. The mechanically durable nanocoatings exhibited excellent antibacterial performance against Staphylococcus aureus and Escherichia coli in a period of 3 days. The nanocoatings with zwitterionic and dopamine segments at the molar ratio of 8:2 were further evaluated and demonstrated durable antibacterial performance after tape-peeling and ultrasonication treatments. (c) 2021 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology.

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