The Immunomodulatory Enzyme IDO2 Mediates Autoimmune Arthritis through a Nonenzymatic Mechanism

IDO2 rs10109853 polymorphism affects the susceptibility to multiple myeloma

(2021) Tetsuhiro Kasamatsu et al.   CLINICAL AND EXPERIMENTAL MEDICINE

IDO1 Signaling Through GCN2 in a Subpopulation of Gr-1+ Cells Shifts the IFNγ/IL6 Balance to Promote Neovascularization

(2021) Souvik Dey et al.   Cancer Immunology Research

Indoleamine 2,3‐dioxygenase 1 (IDO1): an up‐to‐date overview of an eclectic immunoregulatory enzyme

(2021) Maria Teresa Pallotta et al.   FEBS Journal

Differential Roles of IDO1 and IDO2 in T and B Cell Inflammatory Immune Responses

(2020) Lauren M. F. Merlo et al.   Frontiers in Immunology

Anti-GAPDH Autoantibody Is Associated with Increased Disease Activity and Intracranial Pressure in Systemic Lupus Erythematosus

(2019) Jingjing Sun et al.   Journal of Immunology Research

O-GlcNAcylation in immunity and inflammation: An intricate system (Review)

(2019) Yu Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Genetic Polymorphisms Affecting IDO1 or IDO2 Activity Differently Associate With Aspergillosis in Humans

(2019) Valerio Napolioni et al.   Frontiers in Immunology

Scorpins in the DNA Damage Response

(2018) Dario Palmieri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Sub-Type of Familial Pancreatic Cancer: Evidence and Implications of Loss-of-Function Polymorphisms in Indoleamine-2,3-Dioxygenase-2

(2018) Avinoam Nevler et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase

(2018) Maria Winters et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Indoleamine-2,3-dioxygenase(IDO)2 polymorphisms are not associated with multiple sclerosis in Italians

(2017) Cristina Agliardi et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology

(2017) Eddy W. Yue et al.   ACS Medicinal Chemistry Letters

O-GlcNAcylation is required for B cell homeostasis and antibody responses

(2017) Jung-Lin Wu et al.   Nature Communications

Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1

(2016) Elisa Albini et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

IDO2 Modulates T Cell–Dependent Autoimmune Responses through a B Cell–Intrinsic Mechanism

(2016) Lauren M. F. Merlo et al.   JOURNAL OF IMMUNOLOGY

Global Analysis ofO-GlcNAc Glycoproteins in Activated Human T Cells

(2016) Peder J. Lund et al.   JOURNAL OF IMMUNOLOGY

Cancer Immunotherapy by Targeting IDO1/TDO and Their Downstream Effectors

(2015) Michael Platten et al.   Frontiers in Immunology

A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors

(2015) Hatem H. Soliman et al.   Oncotarget

Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1

(2014) Georgios Pantouris et al.   AMINO ACIDS

Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer

(2014) George C. Prendergast et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation

(2014) Richard Metz et al.   INTERNATIONAL IMMUNOLOGY

Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes

(2014) Maria Teresa Pallotta et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

IDO2 Is a Critical Mediator of Autoantibody Production and Inflammatory Pathogenesis in a Mouse Model of Autoimmune Arthritis

(2014) L. M. F. Merlo et al.   JOURNAL OF IMMUNOLOGY

IDO1 and IDO2 Non-Synonymous Gene Variants: Correlation with Crohn's Disease Risk and Clinical Phenotype

(2014) Alexander Lee et al.   PLoS One

Metformin Use and All-Cause and Prostate Cancer–Specific Mortality Among Men With Diabetes

(2013) David Margel et al.   JOURNAL OF CLINICAL ONCOLOGY

The indoleamine 2,3-dioxygenase (IDO) pathway controls allergy

(2012) D. Bubnoff et al.   ALLERGY

Heme Binding Properties of Glyceraldehyde-3-phosphate Dehydrogenase

(2012) Luciana Hannibal et al.   BIOCHEMISTRY

Indoleamine 2,3-dioxygenase as a Modifier of Pathogenic Inflammation in Cancer and other Inflammation-Associated Diseases

(2012) G. C. Prendergast et al.   CURRENT MEDICINAL CHEMISTRY

Indoleamine 2,3-dioxygenase: From catalyst to signaling function

(2012) Francesca Fallarino et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase

(2012) B. Ravishankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

(2012) Richard Metz et al.   OncoImmunology

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

(2011) Maria T Pallotta et al.   NATURE IMMUNOLOGY

Indoleamine 2,3-Dioxygenase

(2010) Hatem Soliman et al.   CANCER JOURNAL

The diverse functions of GAPDH: Views from different subcellular compartments

(2010) Carlos Tristan et al.   CELLULAR SIGNALLING

Indoleamine 2,3 dioxygenase-mediated tryptophan catabolism regulates accumulation of Th1/Th17 cells in the joint in collagen-induced arthritis

(2009) Gabriel Criado et al.   ARTHRITIS AND RHEUMATISM

Indoleamine 2,3-Dioxygenase, an Emerging Target for Anti-Cancer Therapy

(2009) X. Liu et al.   CURRENT CANCER DRUG TARGETS

Ran on tracks - cytoplasmic roles for a nuclear regulator

(2009) D. Yudin et al.   JOURNAL OF CELL SCIENCE

The Immunoregulatory Enzyme IDO Paradoxically Drives B Cell-Mediated Autoimmunity

(2009) G. N. Scott et al.   JOURNAL OF IMMUNOLOGY

Genotyping and Expression Analysis of IDO2 in Human Pancreatic Cancer: A Novel, Active Target

(2009) Agnieszka K. Witkiewicz et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE

Indoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammation

(2008) H. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA