Treatment of two infants with PIK3CA-related overgrowth spectrum by alpelisib

Somatic non-cancerous PIK3CA-related overgrowth syndrome treated with alpelisib in North America

(2021) Alexandre P. Garneau et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Treatment strategies for mosaic overgrowth syndromes of the PI3K-AKT-mTOR pathway

(2021) Gabriel Morin et al.   BRITISH MEDICAL BULLETIN

A review of mechanisms of disease across PIK3CA-related disorders with vascular manifestations

(2021) Guillaume Canaud et al.   Orphanet Journal of Rare Diseases

PIK3CA-Related Overgrowth Spectrum From Diagnosis to Targeted Therapy: A Case of CLOVES Syndrome Treated With Alpelisib

(2021) Angelica Pagliazzi et al.   Frontiers in Pediatrics

Alpelisib administration reduced lymphatic malformations in a mouse model and in patients

(2021) Florence Delestre et al.   Science Translational Medicine

A pharmacokinetic evaluation of alpelisib for the treatment of HR+, HER2-negative, PIK3CA-mutated advanced or metastatic breast cancer

(2020) Marion Bertho et al.   Expert Opinion on Drug Metabolism & Toxicology

Alpelisib for PIK3CA-Mutated, Hormone Receptor–Positive Advanced Breast Cancer

(2019) Fabrice André et al.   NEW ENGLAND JOURNAL OF MEDICINE

ALPELISIB TREATMENT FOR GENITAL VASCULAR MALFORMATION IN CLOVES SYNDROME

(2019) Juan Carlos López Gutiérrez et al.   Journal of Pediatric and Adolescent Gynecology

Pulmonary thromboembolic events in patients with congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and spinal/skeletal abnormalities and Klippel-Trénaunay syndrome

(2018) Joseph Reis et al.   Journal of Vascular Surgery-Venous and Lymphatic Disorders

Safety and efficacy of low-dose sirolimus in the PIK3CA-related overgrowth spectrum

(2018) Victoria E. R. Parker et al.   GENETICS IN MEDICINE

Targeted therapy in patients with PIK3CA-related overgrowth syndrome

(2018) Quitterie Venot et al.   NATURE

Somatic PIK3CA mutations as a driver of sporadic venous malformations

(2016) Pau Castel et al.   Science Translational Medicine

PIK3CA-related overgrowth spectrum (PROS): Diagnostic and testing eligibility criteria, differential diagnosis, and evaluation

(2014) Kim M. Keppler-Noreuil et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

3D Slicer as an image computing platform for the Quantitative Imaging Network

(2012) Andriy Fedorov et al.   MAGNETIC RESONANCE IMAGING

PI3K signalling: the path to discovery and understanding

(2012) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY