FGF21 alleviates acute liver injury by inducing the SIRT1‐autophagy signalling pathway

Liver Regeneration after Acetaminophen Hepatotoxicity: Mechanisms and Therapeutic Opportunities

(2019) Bharat Bhushan et al.   AMERICAN JOURNAL OF PATHOLOGY

Autophagy and acetaminophen-induced hepatotoxicity

(2018) Shulin Shan et al.   ARCHIVES OF TOXICOLOGY

A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo

(2018) Liam D. Cassidy et al.   Autophagy

FGF21 mediates the protective effect of fenofibrate against acetaminophen -induced hepatotoxicity via activating autophagy in mice

(2018) Yi Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

FGF21 is induced in cisplatin nephrotoxicity to protect against kidney tubular cell injury

(2018) Fanghua Li et al.   FASEB JOURNAL

Fish oil alleviates liver injury induced by intestinal ischemia/reperfusion via AMPK/SIRT-1/autophagy pathway

(2018) Hui-Rong Jing et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Mangiferin Improves Hepatic Lipid Metabolism Mainly Through Its Metabolite-Norathyriol by Modulating SIRT-1/AMPK/SREBP-1c Signaling

(2018) Jian Li et al.   Frontiers in Pharmacology

Acute Liver Injury and Failure

(2017) Vincent Thawley   VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE

Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury

(2017) Bhavna N. Desai et al.   Molecular Metabolism

Fibroblast growth factor 21 and its novel association with oxidative stress

(2017) Miguel Ángel Gómez-Sámano et al.   Redox Biology

Salidroside ameliorates sepsis-induced acute lung injury and mortality via downregulating NF-κB and HMGB1 pathways through the upregulation of SIRT1

(2017) Kuo-Cheng Lan et al.   Scientific Reports

Sirt1: Role Under the Condition of Ischemia/Hypoxia

(2016) Xiaofei Meng et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Sirtuin 1 Stimulation Attenuates Ischemic Liver Injury and Enhances Mitochondrial Recovery and Autophagy

(2016) Adam Khader et al.   CRITICAL CARE MEDICINE

Elevated Serum Fibroblast Growth Factor 21 in Humans with Acute Pancreatitis

(2016) Vivek K. Shenoy et al.   PLoS One

Dioscin alleviates BDL- and DMN-induced hepatic fibrosis via Sirt1/Nrf2-mediated inhibition of p38 MAPK pathway

(2016) Lina Gu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Fibroblast growth factor 21 deficiency exacerbates chronic alcohol-induced hepatic steatosis and injury

(2016) Yanlong Liu et al.   Scientific Reports

Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet

(2015) Naoki Tanaka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Matrix metalloproteinases in liver injury, repair and fibrosis

(2015) Sergio Duarte et al.   MATRIX BIOLOGY

Deacetylation of Nuclear LC3 Drives Autophagy Initiation under Starvation

(2015) Rui Huang et al.   MOLECULAR CELL

FGF21 treatment ameliorates alcoholic fatty liver through activation of AMPK-SIRT1 pathway

(2014) S. Zhu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Autophagy as a second level protective process in conferring resistance to environmentally-induced oxidative stress

(2014) Michael N. Moore   Autophagy

Fibroblast Growth Factor 21 Limits Lipotoxicity by Promoting Hepatic Fatty Acid Activation in Mice on Methionine and Choline-Deficient Diets

(2014) Ffolliott M. Fisher et al.   GASTROENTEROLOGY

Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice

(2014) Dewei Ye et al.   HEPATOLOGY

Fibroblast growth factor 21: A new liver safeguard

(2014) Marica Cariello et al.   HEPATOLOGY

Exendin-4 regulates lipid metabolism and fibroblast growth factor 21 in hepatic steatosis

(2014) Jinmi Lee et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Interferon β protects against lethal endotoxic and septic shock through SIRT1 upregulation

(2014) Chae-Hwa Yoo et al.   Scientific Reports

Drug-induced Acute Liver Failure

(2013) William M. Lee   Clinics in Liver Disease

Hepatic SIRT1 Attenuates Hepatic Steatosis and Controls Energy Balance in Mice by Inducing Fibroblast Growth Factor 21

(2013) Yu Li et al.   GASTROENTEROLOGY

Role of activin A in carbon tetrachloride-induced acute liver injury

(2013) Dong-Hui Wang   WORLD JOURNAL OF GASTROENTEROLOGY

Bitter melon extract attenuating hepatic steatosis may be mediated by FGF21 and AMPK/Sirt1 signaling in mice

(2013) Yongmei Yu et al.   Scientific Reports

Resveratrol role in cardiovascular and metabolic health and potential mechanisms of action

(2012) Qiang Xu et al.   NUTRITION RESEARCH

Activation of autophagy protects against acetaminophen-induced hepatotoxicity

(2011) Hong-Min Ni et al.   HEPATOLOGY

Loss of autophagy promotes murine acetaminophen hepatotoxicity

(2011) Yuki Igusa et al.   JOURNAL OF GASTROENTEROLOGY

Fibroblast growth factor 21: from pharmacology to physiology

(2009) Steven A Kliewer et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION